Anti-Retroviral Therapy: Atripla Medication

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which of the following viruses carries its genome on DNA?

  • Hepatitis B (correct)
  • Measles
  • Influenza
  • Hepatitis A

Emtricitabine and tenofovir are both classified as what type of antiviral agents?

  • Pharmacokinetic enhancers
  • Protease inhibitors
  • Non-nucleoside reverse transcriptase inhibitors
  • Nucleoside reverse transcriptase inhibitors (correct)

Which of the following components of Stribld is a pharmacokinetic enhancer?

  • Emtricitabine
  • Elvitegravir
  • Tenofovir disoproxil
  • Cobicistat (correct)

Which of the following antiviral agents is not a current licensed target?

<p>CXCR4 receptor antagonists (A)</p> Signup and view all the answers

Which HIV glycoprotein mediates host membrane fusion?

<p>gp41 (D)</p> Signup and view all the answers

What is the primary mechanism of action of efavirenz?

<p>Inhibiting the action of reverse transcriptase (B)</p> Signup and view all the answers

What enzyme does trimethoprim inhibit?

<p>Dihydrofolate reductase (DHFR) (B)</p> Signup and view all the answers

Why is it unlikely that a 'cure' of HIV is possible with currently available drugs?

<p>Even in combination, current drugs do not completely block viral replication (A)</p> Signup and view all the answers

What is NOT a goal of HIV therapy?

<p>Reduce CD4 cell count (C)</p> Signup and view all the answers

Approximately, how many errors does reverse transcriptase make?

<p>Error-prone, but exact number unknown (C)</p> Signup and view all the answers

What is the mechanism of action of trimethoprim?

<p>Inhibition of dihydrofolate reductase (DHFR) (C)</p> Signup and view all the answers

What is a major concern with currently available HIV drugs?

<p>Even in combination, resistance to current drugs is high (C)</p> Signup and view all the answers

How many nucleotides are removed during proviral cDNA processing?

<p>5 (B)</p> Signup and view all the answers

What is the characteristic of the binding site of rilpivirine to reverse transcriptase?

<p>It is an allosteric binding site next to the substrate binding site (D)</p> Signup and view all the answers

What classification of anti-HIV is rilpivirine?

<p>Non-nucleoside reverse transcriptase inhibitor (NNRTI) (C)</p> Signup and view all the answers

Which divalent cation do integrase inhibitors have high affinity binding to?

<p>Mg2+ (C)</p> Signup and view all the answers

Which amino acid is key to the functioning of the HIV-protease enzyme?

<p>Aspartic acid (B)</p> Signup and view all the answers

What is the decahydroisoquinoline ring system in saquinavir a mimic of?

<p>Aspartic acid (B)</p> Signup and view all the answers

Flashcards are hidden until you start studying

More Like This

Use Quizgecko on...
Browser
Browser