Anti-Retroviral Therapy: Atripla Medication
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Questions and Answers

Which of the following viruses carries its genome on DNA?

  • Hepatitis B (correct)
  • Measles
  • Influenza
  • Hepatitis A

    • Emtricitabine and tenofovir are both classified as what type of antiviral agents?

  • Pharmacokinetic enhancers
  • Protease inhibitors
  • Non-nucleoside reverse transcriptase inhibitors
  • Nucleoside reverse transcriptase inhibitors (correct)

    • Which of the following components of Stribld is a pharmacokinetic enhancer?

  • Emtricitabine
  • Elvitegravir
  • Tenofovir disoproxil
  • Cobicistat (correct)

    • Which of the following antiviral agents is not a current licensed target?

    <p>CXCR4 receptor antagonists</p> Signup and view all the answers

    Which HIV glycoprotein mediates host membrane fusion?

    <p>gp41</p> Signup and view all the answers

    What is the primary mechanism of action of efavirenz?

    <p>Inhibiting the action of reverse transcriptase</p> Signup and view all the answers

    What enzyme does trimethoprim inhibit?

    <p>Dihydrofolate reductase (DHFR)</p> Signup and view all the answers

    Why is it unlikely that a 'cure' of HIV is possible with currently available drugs?

    <p>Even in combination, current drugs do not completely block viral replication</p> Signup and view all the answers

    What is NOT a goal of HIV therapy?

    <p>Reduce CD4 cell count</p> Signup and view all the answers

    Approximately, how many errors does reverse transcriptase make?

    <p>Error-prone, but exact number unknown</p> Signup and view all the answers

    What is the mechanism of action of trimethoprim?

    <p>Inhibition of dihydrofolate reductase (DHFR)</p> Signup and view all the answers

    What is a major concern with currently available HIV drugs?

    <p>Even in combination, resistance to current drugs is high</p> Signup and view all the answers

    How many nucleotides are removed during proviral cDNA processing?

    <p>5</p> Signup and view all the answers

    What is the characteristic of the binding site of rilpivirine to reverse transcriptase?

    <p>It is an allosteric binding site next to the substrate binding site</p> Signup and view all the answers

    What classification of anti-HIV is rilpivirine?

    <p>Non-nucleoside reverse transcriptase inhibitor (NNRTI)</p> Signup and view all the answers

    Which divalent cation do integrase inhibitors have high affinity binding to?

    <p>Mg2+</p> Signup and view all the answers

    Which amino acid is key to the functioning of the HIV-protease enzyme?

    <p>Aspartic acid</p> Signup and view all the answers

    What is the decahydroisoquinoline ring system in saquinavir a mimic of?

    <p>Aspartic acid</p> Signup and view all the answers

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