Podcast
Questions and Answers
Which drug is associated with a slower recovery of psychomotor function compared to propofol?
Which drug is associated with a slower recovery of psychomotor function compared to propofol?
What is the effect of increasing the dose of etomidate or administering it as a continuous infusion?
What is the effect of increasing the dose of etomidate or administering it as a continuous infusion?
Which drug can be useful to blunt the hemodynamic responses evoked by direct laryngoscopy and tracheal intubation when administered before induction of anesthesia with etomidate?
Which drug can be useful to blunt the hemodynamic responses evoked by direct laryngoscopy and tracheal intubation when administered before induction of anesthesia with etomidate?
What is the principal limiting factor in the clinical use of etomidate for induction of anesthesia?
What is the principal limiting factor in the clinical use of etomidate for induction of anesthesia?
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Which of the following is true about the effects of etomidate on myocardial contractility?
Which of the following is true about the effects of etomidate on myocardial contractility?
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Which of the following is true about the effects of etomidate on hepatic and renal functions?
Which of the following is true about the effects of etomidate on hepatic and renal functions?
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Which of the following is true about the effects of etomidate on intraocular pressure?
Which of the following is true about the effects of etomidate on intraocular pressure?
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Which of the following is true about the effects of etomidate on ventilation?
Which of the following is true about the effects of etomidate on ventilation?
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Which of the following statements about propofol is true?
Which of the following statements about propofol is true?
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Which of the following is true about the original formulation of etomidate?
Which of the following is true about the original formulation of etomidate?
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Which of the following statements about etomidate is true?
Which of the following statements about etomidate is true?
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According to the text, what is the duration of enzyme inhibition after an induction dose of etomidate?
According to the text, what is the duration of enzyme inhibition after an induction dose of etomidate?
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According to the text, what impact does etomidate have on mortality, length of ICU stay, and duration of mechanical ventilation in trauma patients?
According to the text, what impact does etomidate have on mortality, length of ICU stay, and duration of mechanical ventilation in trauma patients?
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According to the text, what is the incidence of allergic reactions following administration of etomidate?
According to the text, what is the incidence of allergic reactions following administration of etomidate?
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According to the text, what are the five principal pharmacologic effects of benzodiazepines?
According to the text, what are the five principal pharmacologic effects of benzodiazepines?
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Etomidate exerts its effects on GABAA receptors by binding directly to a specific site or sites on the protein and enhancing the affinity of the inhibitory neurotransmitter (GABA) for these receptors. Which of the following statements about etomidate is true?
Etomidate exerts its effects on GABAA receptors by binding directly to a specific site or sites on the protein and enhancing the affinity of the inhibitory neurotransmitter (GABA) for these receptors. Which of the following statements about etomidate is true?
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Which of the following is NOT a characteristic of etomidate's distribution in the body?
Which of the following is NOT a characteristic of etomidate's distribution in the body?
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What is the primary reason for the prompt awakening after a single dose of etomidate?
What is the primary reason for the prompt awakening after a single dose of etomidate?
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How does etomidate metabolism differ from propofol metabolism?
How does etomidate metabolism differ from propofol metabolism?
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Which of the following is true about the metabolism of etomidate?
Which of the following is true about the metabolism of etomidate?
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What is the primary reason for the use of propofol in patients with hereditary coproporphyria?
What is the primary reason for the use of propofol in patients with hereditary coproporphyria?
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What is the mechanism of action of etomidate?
What is the mechanism of action of etomidate?
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Which of the following statements about etomidate is true?
Which of the following statements about etomidate is true?
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What is the primary reason for the prompt awakening after a single dose of etomidate?
What is the primary reason for the prompt awakening after a single dose of etomidate?
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What is the effect of increasing the dose of etomidate or administering it as a continuous infusion?
What is the effect of increasing the dose of etomidate or administering it as a continuous infusion?
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Which drug can be useful to blunt the hemodynamic responses evoked by direct laryngoscopy and tracheal intubation when administered before induction of anesthesia with etomidate?
Which drug can be useful to blunt the hemodynamic responses evoked by direct laryngoscopy and tracheal intubation when administered before induction of anesthesia with etomidate?
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Which of the following is true about the effects of etomidate on cortisol levels?
Which of the following is true about the effects of etomidate on cortisol levels?
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Which of the following is true about the incidence of allergic reactions following administration of etomidate?
Which of the following is true about the incidence of allergic reactions following administration of etomidate?
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Which of the following is NOT one of the pharmacologic effects of benzodiazepines?
Which of the following is NOT one of the pharmacologic effects of benzodiazepines?
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Which of the following is true about the effects of etomidate on mortality and morbidity in cardiac surgical patients?
Which of the following is true about the effects of etomidate on mortality and morbidity in cardiac surgical patients?
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Which of the following is true about the effects of etomidate on cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO2)?
Which of the following is true about the effects of etomidate on cerebral blood flow (CBF) and cerebral metabolic rate of oxygen (CMRO2)?
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Which of the following is a characteristic of etomidate's effects on the EEG?
Which of the following is a characteristic of etomidate's effects on the EEG?
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Which of the following statements about the cardiovascular effects of etomidate is true?
Which of the following statements about the cardiovascular effects of etomidate is true?
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Which of the following is a consideration when using etomidate for induction of anesthesia in patients with little or no cardiac reserve?
Which of the following is a consideration when using etomidate for induction of anesthesia in patients with little or no cardiac reserve?
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Which of the following statements about the effects of etomidate on myocardial contractility is true?
Which of the following statements about the effects of etomidate on myocardial contractility is true?
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Which of the following statements about the effects of etomidate on ventilation is true?
Which of the following statements about the effects of etomidate on ventilation is true?
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Which of the following statements about pain on injection of etomidate is true?
Which of the following statements about pain on injection of etomidate is true?
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Which of the following statements about etomidate-induced myoclonus is true?
Which of the following statements about etomidate-induced myoclonus is true?
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True or false: Propofol can trigger malignant hyperthermia.
True or false: Propofol can trigger malignant hyperthermia.
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True or false: Propofol can influence the secretion of cortisol.
True or false: Propofol can influence the secretion of cortisol.
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True or false: Etomidate is a carboxylated imidazole–containing compound.
True or false: Etomidate is a carboxylated imidazole–containing compound.
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True or false: Full recovery of psychomotor function after administration of etomidate is faster than following use of propofol.
True or false: Full recovery of psychomotor function after administration of etomidate is faster than following use of propofol.
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True or false: Etomidate produces analgesia similar to barbiturates and propofol.
True or false: Etomidate produces analgesia similar to barbiturates and propofol.
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True or false: Etomidate has minimal effects on the duration of electrically induced seizures.
True or false: Etomidate has minimal effects on the duration of electrically induced seizures.
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True or false: Etomidate is a potent direct cerebral vasodilator that increases cerebral blood flow.
True or false: Etomidate is a potent direct cerebral vasodilator that increases cerebral blood flow.
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Etomidate administration can lead to an intact cortisol response in patients with sepsis or hemorrhage.
Etomidate administration can lead to an intact cortisol response in patients with sepsis or hemorrhage.
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Suppression of adrenocortical function is always desirable during anesthesia.
Suppression of adrenocortical function is always desirable during anesthesia.
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The use of etomidate has been shown to have no impact on mortality or length of ICU stay in trauma patients.
The use of etomidate has been shown to have no impact on mortality or length of ICU stay in trauma patients.
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Etomidate exposure is associated with longer length of hospital stay in cardiac surgical patients.
Etomidate exposure is associated with longer length of hospital stay in cardiac surgical patients.
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True or false: Etomidate is more selective as a modulator of GABAA receptors compared to barbiturates.
True or false: Etomidate is more selective as a modulator of GABAA receptors compared to barbiturates.
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True or false: Etomidate binds directly to GABAA receptors and enhances the affinity of GABA for these receptors.
True or false: Etomidate binds directly to GABAA receptors and enhances the affinity of GABA for these receptors.
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True or false: Etomidate is known to modulate other ligand-gated ion channels in the brain at clinically relevant concentrations.
True or false: Etomidate is known to modulate other ligand-gated ion channels in the brain at clinically relevant concentrations.
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True or false: Etomidate is rapidly metabolized by hydrolysis of the ethyl ester side chain to its carboxylic acid ester, resulting in a pharmacologically active compound.
True or false: Etomidate is rapidly metabolized by hydrolysis of the ethyl ester side chain to its carboxylic acid ester, resulting in a pharmacologically active compound.
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True or false: Etomidate has minimal depressive effects on myocardial contractility at concentrations needed for anesthesia.
True or false: Etomidate has minimal depressive effects on myocardial contractility at concentrations needed for anesthesia.
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True or false: Etomidate-induced decreases in tidal volume are offset by compensatory increases in the frequency of breathing.
True or false: Etomidate-induced decreases in tidal volume are offset by compensatory increases in the frequency of breathing.
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True or false: Etomidate can cause excitatory effects such as myoclonus in a high percentage of patients.
True or false: Etomidate can cause excitatory effects such as myoclonus in a high percentage of patients.
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True or false: Etomidate causes adrenocortical suppression by inhibiting the conversion of cholesterol to cortisol.
True or false: Etomidate causes adrenocortical suppression by inhibiting the conversion of cholesterol to cortisol.
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Which of the following is a potential disadvantage of administering etomidate to patients experiencing sepsis or hemorrhage?
Which of the following is a potential disadvantage of administering etomidate to patients experiencing sepsis or hemorrhage?
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Which of the following statements is supported by at least one report?
Which of the following statements is supported by at least one report?
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Which of the following statements is NOT supported by the retrospective study of cardiac surgical patients?
Which of the following statements is NOT supported by the retrospective study of cardiac surgical patients?
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Which of the following is a potential advantage of administering etomidate for induction of anesthesia?
Which of the following is a potential advantage of administering etomidate for induction of anesthesia?
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Which drug was associated with increased 30-day mortality and cardiovascular morbidity after noncardiac surgery in a large-scale retrospective study?
Which drug was associated with increased 30-day mortality and cardiovascular morbidity after noncardiac surgery in a large-scale retrospective study?
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Which of the following statements about allergic reactions to etomidate is true?
Which of the following statements about allergic reactions to etomidate is true?
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Which of the following is NOT a pharmacologic effect of benzodiazepines?
Which of the following is NOT a pharmacologic effect of benzodiazepines?
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Which of the following statements about etomidate's effects on tidal volume and frequency of breathing is true?
Which of the following statements about etomidate's effects on tidal volume and frequency of breathing is true?
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Which drug has a faster recovery of psychomotor function compared to etomidate?
Which drug has a faster recovery of psychomotor function compared to etomidate?
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Which of the following statements about etomidate's mechanism of action is true?
Which of the following statements about etomidate's mechanism of action is true?
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