Anatomy & Functions of the Liver and Gallbladder
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Questions and Answers

What is the primary function of the gallbladder?

  • Filters blood from the portal vein
  • Stores and concentrates bile (correct)
  • Produces bile
  • Secrets insulin into the bloodstream

    • Which statement about the portal vein is correct?

  • Supplies 75% of the liver's blood (correct)
  • Is formed only by the splenic vein
  • Drains blood from the liver into the inferior vena cava
  • Is the main vessel draining the gallbladder

    • What condition is characterized by increased pressure in the portal venous system?

  • Cholelithiasis
  • Murphy's Sign
  • Portal Hypertension (correct)
  • Hepatomegaly

    • What anatomical feature connects the gallbladder to the biliary system?

    <p>Cystic duct</p> Signup and view all the answers

    Which imaging technique is specifically used for diagnosing pathologies of the common bile duct?

    <p>MRCP</p> Signup and view all the answers

    Which anatomic part of the gallbladder is defined as the main central portion?

    <p>Body</p> Signup and view all the answers

    What is the role of the Sphincter of Oddi in relation to the biliary system?

    <p>Opens to release bile during digestion</p> Signup and view all the answers

    Which symptom is indicative of cholecystitis and often assessed using Murphy's Sign?

    <p>Tenderness in the RUQ on deep inspiration</p> Signup and view all the answers

    What is the approximate weight of the liver relative to body weight?

    <p>2% of body weight</p> Signup and view all the answers

    Which of the following structures separates the right and left lobes of the liver?

    <p>Falciform ligament</p> Signup and view all the answers

    What is a primary function of the Kupffer cells in the liver?

    <p>Clearing pathogens</p> Signup and view all the answers

    What is contained within the lesser omentum?

    <p>Bile duct, hepatic artery, portal vein</p> Signup and view all the answers

    Which of the following statements about the anatomical lobes of the liver is true?

    <p>The left lobe includes the quadrate and caudate lobes.</p> Signup and view all the answers

    What percentage of the liver's blood supply is provided by the hepatic artery?

    <p>25%</p> Signup and view all the answers

    What is the primary role of the liver in metabolism?

    <p>Synthesis of glucose and fats</p> Signup and view all the answers

    What is Morison's Pouch also known as?

    <p>Hepatorenal recess</p> Signup and view all the answers

    Which of the following structures demarcates the bare area of the liver?

    <p>Coronary ligament</p> Signup and view all the answers

    What percentage of the liver’s blood supply is provided by the portal vein?

    <p>75%</p> Signup and view all the answers

    Which structure is located at the porta hepatis?

    <p>Portal vein</p> Signup and view all the answers

    What is the primary function of the gallbladder?

    <p>Storage and concentration of bile</p> Signup and view all the answers

    A patient presents with right upper quadrant pain and a positive Murphy's sign. What is the most likely diagnosis?

    <p>Cholecystitis</p> Signup and view all the answers

    Porto-systemic anastomoses become clinically relevant in which condition?

    <p>Portal hypertension</p> Signup and view all the answers

    Which of the following is NOT a part of the common bile duct?

    <p>Pancreatic duct</p> Signup and view all the answers

    The round ligament (ligamentum teres) is the remnant of which fetal structure?

    <p>Umbilical vein</p> Signup and view all the answers

    The liver is divided into eight functional segments based on which two factors?

    <p>Biliary drainage and blood supply</p> Signup and view all the answers

    Where do the superficial lymphatics of the liver primarily drain?

    <p>Hepatic lymph nodes</p> Signup and view all the answers

    Which maneuver is used to control bleeding from the liver during surgery?

    <p>Pringle's maneuver</p> Signup and view all the answers

    The portal vein is formed by the union of which two veins?

    <p>Splenic and superior mesenteric veins</p> Signup and view all the answers

    In portal hypertension, which site is most commonly associated with the formation of varices?

    <p>Esophagus</p> Signup and view all the answers

    Which of the following is another common site where varices form due to portal hypertension?

    <p>Umbilicus</p> Signup and view all the answers

    Why are porto-systemic anastomoses clinically relevant in portal hypertension?

    <p>They lead to varices, which may rupture and cause life-threatening bleeding.</p> Signup and view all the answers

    Which of the following surfaces of the liver is in contact with the diaphragm?

    <p>Bare area</p> Signup and view all the answers

    Which anatomical structure separates the right and left lobes of the liver anteriorly?

    <p>Falciform ligament</p> Signup and view all the answers

    Which two vessels provide the liver’s blood supply?

    <p>Hepatic artery and portal vein</p> Signup and view all the answers

    Where is the pancreas located in relation to the stomach?

    <p>Posterior to the stomach</p> Signup and view all the answers

    Which duct joins the common bile duct before draining into the duodenum at the major duodenal papilla?

    <p>Pancreatic duct</p> Signup and view all the answers

    Acute pancreatitis is most commonly caused by which of the following?

    <p>Gallstones and alcohol abuse</p> Signup and view all the answers

    Lymph from the liver primarily drains into which group of nodes?

    <p>Hepatic lymph nodes</p> Signup and view all the answers

    Where do the hepatic veins drain the blood from the liver?

    <p>Inferior vena cava</p> Signup and view all the answers

    Which of the following is NOT a function of the pancreas?

    <p>Bile production</p> Signup and view all the answers

    Which structure is responsible for transporting bile from the liver and gallbladder to the duodenum?

    <p>Common bile duct</p> Signup and view all the answers

    Which veins combine to form the portal vein?

    <p>Splenic vein and superior mesenteric vein</p> Signup and view all the answers

    What is the consequence of increased pressure in the portal venous system (portal hypertension)?

    <p>Variceal bleeding</p> Signup and view all the answers

    What is the role of the gallbladder in the digestive system?

    <p>Storing and concentrating bile</p> Signup and view all the answers

    Which arteries supply blood to the pancreas?

    <p>Splenic artery and branches of the superior mesenteric artery</p> Signup and view all the answers

    The pancreas performs both endocrine and exocrine functions. Which of the following is an exocrine function of the pancreas?

    <p>Digestive enzyme secretion</p> Signup and view all the answers

    Where is the major duodenal papilla located, and what drains into it?

    <p>Second part of the duodenum; bile and pancreatic juice</p> Signup and view all the answers

    Which ligament attaches the liver to the anterior abdominal wall?

    <p>Falciform ligament</p> Signup and view all the answers

    Liver segments are functionally independent units based on what criteria?

    <p>Blood supply and biliary drainage</p> Signup and view all the answers

    Which of the following is NOT a tributary of the hepatic portal vein?

    <p>Hepatic vein</p> Signup and view all the answers

    The gallbladder is located on the visceral surface of which liver lobe?

    <p>Right lobe</p> Signup and view all the answers

    Study Notes

    Liver: Overview

    • Largest gland in the body, approximately 1500g, accounting for ~2% of body weight.
    • Receives around 1500ml of blood per minute.
    • Located in the right upper abdomen, from the 4th right intercostal space to the costal margin.
    • Lies beneath ribs 7-11; can be palpated during inspiration.

    Functions of the Liver

    • Synthesis of proteins such as albumin and clotting factors.
    • Metabolizes fats, carbohydrates, and proteins.
    • Inactivates toxins, including drugs and alcohol.
    • Produces bile for fat digestion and absorption.
    • Stores glucose as glycogen and releases it when needed.
    • Synthesizes cholesterol.
    • Processes hemoglobin, converting heme to bilirubin.
    • Regulates blood clotting mechanisms.
    • Participates in immune responses via Kupffer cells that clear pathogens.
    • Clears bilirubin from the breakdown of red blood cells.

    Liver Anatomy

    • Surface Anatomy:
      • Diaphragmatic surface: Convex, facing anteriorly, superiorly, and posteriorly.
      • Visceral surface: Concave, contacts gallbladder and peritoneum.

    Peritoneal Recesses and Ligaments

    • Recesses:
      • Subphrenic recess: Between the diaphragm and anterior liver surface.
      • Morison’s pouch: Between the liver and right kidney/suprarenal gland; contains peritoneal fluid.
    • Ligaments:
      • Falciform ligament: Attaches liver to anterior abdominal wall; divides liver into right and left lobes.
      • Coronary ligament: Reflects peritoneum from diaphragm, marking the liver's bare area.
      • Triangular ligaments: Right and left, located at edges of the coronary ligament.
      • Lesser omentum: Houses the portal triad (bile duct, hepatic artery, portal vein) within the hepatoduodenal ligament.
      • Round ligament (ligamentum teres): Fibrous remnant of umbilical vein, runs with the falciform ligament.

    Liver Lobes and Segments

    • Anatomical lobes:
      • Right lobe: Larger and separated from the left lobe by the falciform ligament.
      • Left lobe: Smaller, includes quadrate and caudate lobes.
    • Functional segments: Eight segments defined by vascular and biliary drainage, operate independently.

    Vasculature of the Liver

    • Hepatic artery proper: Supplies 25% of blood to the liver.
    • Portal vein: Provides 75% of blood, formed by superior mesenteric and splenic veins.
    • Hepatic veins: Drain deoxygenated blood from liver to inferior vena cava (IVC).

    Portal Venous System & Porto-Systemic Anastomoses

    • Portal venous system: Drains blood from gastrointestinal tract and spleen into the liver.
    • Porto-systemic anastomoses: Connections between portal system and systemic circulation, significant in portal hypertension (e.g., esophageal varices).

    Biliary Tree and Gallbladder

    • Gallbladder Anatomy:
      • Situated in gallbladder fossa on the liver's visceral surface, near the quadrate lobe.
      • Comprises three parts: fundus, body, and neck (which connects to cystic duct).
    • Biliary System Components:
      • Common bile duct (CBD): Formed by the cystic duct and common hepatic duct; has three segments: supraduodenal, retroduodenal, paraduodenal.
    • Gallbladder Function: Stores and concentrates bile (50 mL capacity).

    Major Duodenal Papilla

    • Opening where common bile duct and pancreatic duct enter the duodenum, regulated by the Sphincter of Oddi.

    Blood Supply to the Gallbladder

    • Cystic artery: Usually branches from right hepatic artery.
    • Venous drainage: Cystic vein drains into the portal vein.

    Liver and Gallbladder: Clinical Correlations

    • Liver Conditions:
      • Portal hypertension: Increased pressure due to liver cirrhosis; leads to varices and ascites.
      • Pringle’s maneuver: Surgical technique for controlling liver hemorrhage.
      • Hepatomegaly: Liver enlargement caused by infections, storage disorders, or cirrhosis.
    • Gallbladder Conditions:
      • Cholelithiasis (gallstones): Formed from cholesterol; can block biliary tree.
      • Murphy’s sign: Tenderness in right upper quadrant on inspiration, indicates cholecystitis.
      • Diagnosis methods: Ultrasound, MRCP (Magnetic Resonance Cholangiopancreatography), ERCP (Endoscopic Retrograde Cholangiopancreatography).

    Radiological Imaging

    • Imaging techniques such as ultrasound, CT, and MRI visualize the liver, gallbladder, and bile ducts.
    • Specialized imaging (MRCP, ERCP) aids in diagnosing common bile duct and gallbladder pathologies.

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    Description

    Explore the anatomy and functions of the liver, biliary tree, and gallbladder in this informative quiz. Learn about blood supply, location, and key functions such as protein synthesis and metabolism. Ideal for students studying human anatomy.

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