Anatomic Pathology: Disease Processes

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Questions and Answers

Which of the following best describes the focus of anatomic pathology?

  • The study of cells and their functions.
  • The identification of unknown disease origins.
  • The study of disease or illness states visible in organs or the body. (correct)
  • The analysis of tissue cuts under a microscope.

Histopathology involves evaluating tissue samples at a macroscopic level to identify diseases.

False (B)

Define cytopathology and provide an example of its application.

Cytopathology involves examining cells under a microscope to identify pathological conditions. A Pap smear is an example, used to detect cervical cancer.

Congenital diseases are ______ diseases, potentially passed down through genes.

<p>inborn</p> Signup and view all the answers

Which of the following is NOT typically associated with acquired diseases?

<p>Genetic inheritance. (B)</p> Signup and view all the answers

What characterizes idiopathic diseases?

<p>Their origins are unknown. (B)</p> Signup and view all the answers

Match the stages of inflammation with their descriptions:

<p>Acute Inflammation = Characterized by initial symptoms such as redness, swelling, and pain. Sub-acute Inflammation = An intermediate state between acute and chronic inflammation.</p> Signup and view all the answers

What occurs if the body cannot rid itself of foreign antigens and antibiotics are not administered?

<p>A state of inflammation occurs. (C)</p> Signup and view all the answers

Which characteristic is NOT typically associated with the chronic stage of inflammation?

<p>Rapid and complete healing (A)</p> Signup and view all the answers

Bacteremia is characterized by a rapid increase of bacteria in the blood, leading to a high fever and convulsions.

<p>False (B)</p> Signup and view all the answers

What is the primary difference between bacteremia and septicemia regarding the presence of bacteria in the blood?

<p>Bacteremia is the presence of bacteria in the blood without signs of increasing, whereas septicemia involves an increase of bacteria in the blood.</p> Signup and view all the answers

A(n) ________ is a soft, round mass that can be felt with the fingers and may form during the resolution stage of inflammation.

<p>granuloma</p> Signup and view all the answers

Match each stage of advanced inflammation with its defining characteristic:

<p>Bacteremia = Presence of bacteria in the blood without rapidly increasing. Septicemia = Increase of bacteria in the blood with high fever and possible abscess formation. Pyaemia = Formation of septic thrombi leading to septic embolisms and abscesses throughout the body.</p> Signup and view all the answers

What is a septic thrombus, and in which condition does it play a significant role?

<p>A collection of red and white blood cells infiltrated by pathogens; pyaemia (C)</p> Signup and view all the answers

The resolution stage of inflammation always results in a scar.

<p>False (B)</p> Signup and view all the answers

Describe the progression of systemic infection from bacteremia to pyaemia, outlining the key changes and complications that occur at each stage.

<p>Bacteremia starts with the presence of bacteria in the blood. If it progresses, it becomes septicemia, characterized by a rapid increase in bacteria, fever, and potential abscess formation. If untreated, septicemia can evolve into pyaemia, where septic thrombi form and spread throughout the body, leading to multiple abscesses and a critical, potentially fatal condition.</p> Signup and view all the answers

Flashcards

Pathology

The study of diseased or abnormal states in the body.

Anatomic Pathology

Deals with the examination of organs and tissues affected by disease, often visible to the naked eye.

Histopathology

The study of tissues at a microscopic level to identify signs of disease.

Cytopathology

The study of cells, especially for identifying diseases like cancer.

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Congenital Diseases

Diseases present at birth that can be inherited.

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Acquired Diseases

Diseases that develop after birth due to external factors.

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Idiopathic Diseases

Diseases with an unknown cause or origin.

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Inflammation Signs

Body's response to harmful stimuli, involving redness, swelling, pain, heat and loss of function.

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Chronic Inflammation

Inflammation that persists for a long time, making healing difficult.

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Resolution Stage

Inflammation resolves completely, leaving a scar or granuloma.

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Bacteraemia

Bacteria present in the blood, but not increasing.

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Septicaemia

Bacteria multiplying rapidly in the blood.

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Septicaemia Symptoms

Blood infection with high fever, shivering, and potential abscess formation.

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Pyaemia

A very dangerous state where septic thrombi cause abscesses throughout the body.

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Septic Thrombus Formation

Clogging of red and white blood cells infiltrated by pathogens, forming septic thrombi.

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Septic Embolism

Fragments of a septic thrombus that travel and cause abscesses in other organs.

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Study Notes

  • Pathology studies the different states of disease or illness

Anatomic Pathology

  • Anatomic pathology diagnoses visible diseased states in organs or the body.

Histophathology

  • Histology studies tissues
  • Histopathology identifies pathological conditions by evaluating tissue cuts under a microscope
  • Tissue cuts are analyzed under a microscope to study them

Cytopathology

  • Cytology studies cells
  • Cytopathology is used to diagnose pathological conditions of cells under a microscope
  • Pap smears are a form of cytolopathology used to test for cancer

Disease Classification

  • Congenital diseases are inborn, such as heart diseases, and can be transmitted through genes to offspring.
  • Acquired diseases result from contracting in healthy person to a disease due to malnutrition, trauma, X-rays, pathogenic, microorganisms, or the body's degeneration
  • Idiopathic diseases occur when the origin of a disease is unknown

Infection and Inflammation

  • Infections start when contamination occurs with pathogenic microorganisms
  • Inflammation results when the body cannot rid itself of foreign antigens without antibiotics being administered to counteract infection, or as a reaction of the body's tissues

Signs and Symptoms of Inflammation

  • Redness
  • Swelling
  • Pain
  • Area feels warm
  • Loss of tissue function

Stages of Inflammation

  • Acute inflammation occurs when there is an increase in micro-organisms, and the defense mechanisms are unable to offer resistance
  • Sub-acute inflammation: is an intermediary state between acute and chronic inflammation, where healing may still occur or it may become chronic
  • Chronic inflammation: occurs when inflammation stretches over a long period, and is characterized by chronic pus secretion, formation of connective tissue that results in a scar, or the forming of granulation tissue which leaves no scar but forms a granuloma
  • Resolution stages: indicates that inflammation has completely healed however leaves either a scar, the presence of an erupted abscess or fistula, or an abscess with two openings

Complications of Inflammation

  • Bacteraemia: is identified when bacteria is in the blood without signs of increasing which causes the patient to feel ill, listless, and may be feverish
  • Septicaemia: is identified when there is an increase of bacteria in the blood, which can cause a high temperature above 38 degrees, with alternating bouts of sweating and shivering and potentially leading to convulsions and abscesses
  • Pyaemia: Occurs when red and white blood cells are clogged together, infiltrated by many pathogenic microorganisms, forming a septic thrombus that breaks up leading to septic embolism, with resolution possible it is considered a dangerous state that may lead to death

Previous Exam Questions (November 2014) :

  • Histopathology is thus the identification of pathological conditions by the study of tissue cuts under a microscope
  • Granuloma is a soft, round mass which can be felt with the fingers
  • Resolution stage refers to the recovering stage

Previous Exam Questions (June 2014) :

  • Chronic Stage of Inflammation: Healing is very difficult but fails in some cases and characterized by chronic secretion of pus, the formation of connective tissue which results in a scar or forming of granulation tissue which also leaves no scar but forms a granuloma

Previous Exam Questions (November 2015) :

  • Congenital illnesses are those you are born with
  • Acute conditions are quick and dramatic till the end

Previous Exam Questions (June 2015) :

  • Cytology is the study of cells

Previous Exam Questions (November 2018 and June 2018):

  • Cronic stages in occur when inflammation is long duration
  • Resolution may still occur but it is a very dangerous state and may results in death if not treated properly is relevant of Pyaemia

Previous Exam Questions (September 2020):

  • Inflammation is a protective response to injury TRUE

Previous Exam Questions (November 2021):

  • Septicaemia may be life-threatening TRUE

Previous Exam Questions (June 2021):

  • Septicaemia is an infection of the blood stream or blood poisoning there is an increase of bacteria in the blood

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