Anaphylaxis and IgE-mediated Hypersensitivity Quiz
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Questions and Answers

What is the main cause of an anaphylactoid reaction?

  • Involving antibodies
  • Response to specific drugs
  • Release of histamine and other agents
  • Direct release of mediators from inflammatory cells (correct)

Which of the following is a common precipitant of anaphylaxis?

  • Aspirin
  • Bananas
  • Broccoli
  • Contrast media in radiology (correct)

What are the danger signs of anaphylaxis?

  • Skin rash and itching
  • Fatigue and dizziness
  • High fever and chills
  • Rapid progression of symptoms and evidence of respiratory distress (correct)

What are the clinical features of anaphylaxis?

<p>Urticaria, oedema, and cyanosis (A)</p> Signup and view all the answers

Which condition is NOT a mimic of anaphylaxis?

<p>Migraine (D)</p> Signup and view all the answers

What type of hypersensitivity reaction is anaphylaxis?

<p>Type I IgE-mediated hypersensitivity reaction (A)</p> Signup and view all the answers

What dosage of adrenaline should be injected intramuscularly in the mid-outer thigh for children?

<p>0.01 mg/kg (B)</p> Signup and view all the answers

What is the first and most important therapy in anaphylaxis?

<p>Adrenaline (epinephrine) (D)</p> Signup and view all the answers

What should be given if there are signs of poor perfusion and symptoms are not responding to adrenaline injections?

<p>Normal saline rapid bolus (A)</p> Signup and view all the answers

When should epinephrine be repeated if there is no response or the response is inadequate?

<p>Every 5 to 15 minutes (C)</p> Signup and view all the answers

What should be given if still hypotensive after initial treatment and admission to ICU is needed?

<p>Aminophylline and nebulized salbutamol (A)</p> Signup and view all the answers

What is the maximum recommended dose of adrenaline for large children (>50 kg) when injected intramuscularly?

<p>0.5 mg per dose (A)</p> Signup and view all the answers

What should be monitored after suspected anaphylaxis in adults?

<p>Serum tryptase 1–6h after suspected anaphylaxis (C)</p> Signup and view all the answers

What can help identify allergens to avoid in adults?

<p>Skin-prick tests showing specific IgE (D)</p> Signup and view all the answers

What should be done after suspected anaphylaxis to prevent a fatal attack in adults?

<p>.3mg Epipen® self-injected adrenaline (A)</p> Signup and view all the answers

What is the first and most important therapy in anaphylaxis in pediatric patients?

<p>IM epinephrine injection (B)</p> Signup and view all the answers

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