16 Questions
What is the main cause of an anaphylactoid reaction?
Direct release of mediators from inflammatory cells
Which of the following is a common precipitant of anaphylaxis?
Contrast media in radiology
What are the danger signs of anaphylaxis?
Rapid progression of symptoms and evidence of respiratory distress
What are the clinical features of anaphylaxis?
Urticaria, oedema, and cyanosis
Which condition is NOT a mimic of anaphylaxis?
Migraine
What type of hypersensitivity reaction is anaphylaxis?
Type I IgE-mediated hypersensitivity reaction
What dosage of adrenaline should be injected intramuscularly in the mid-outer thigh for children?
0.01 mg/kg
What is the first and most important therapy in anaphylaxis?
Adrenaline (epinephrine)
What should be given if there are signs of poor perfusion and symptoms are not responding to adrenaline injections?
Normal saline rapid bolus
When should epinephrine be repeated if there is no response or the response is inadequate?
Every 5 to 15 minutes
What should be given if still hypotensive after initial treatment and admission to ICU is needed?
Aminophylline and nebulized salbutamol
What is the maximum recommended dose of adrenaline for large children (>50 kg) when injected intramuscularly?
0.5 mg per dose
What should be monitored after suspected anaphylaxis in adults?
Serum tryptase 1–6h after suspected anaphylaxis
What can help identify allergens to avoid in adults?
Skin-prick tests showing specific IgE
What should be done after suspected anaphylaxis to prevent a fatal attack in adults?
.3mg Epipen® self-injected adrenaline
What is the first and most important therapy in anaphylaxis in pediatric patients?
IM epinephrine injection
Test your knowledge on the type I IgE-mediated hypersensitivity reaction known as anaphylaxis. Explore the release of histamine and other agents causing symptoms such as capillary leak, wheezing, cyanosis, and more. Learn about the differences between anaphylactic and anaphylactoid reactions.
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