Anaphylaxis and IgE-mediated Hypersensitivity Quiz
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Questions and Answers

What is the main cause of an anaphylactoid reaction?

  • Involving antibodies
  • Response to specific drugs
  • Release of histamine and other agents
  • Direct release of mediators from inflammatory cells (correct)
  • Which of the following is a common precipitant of anaphylaxis?

  • Aspirin
  • Bananas
  • Broccoli
  • Contrast media in radiology (correct)
  • What are the danger signs of anaphylaxis?

  • Skin rash and itching
  • Fatigue and dizziness
  • High fever and chills
  • Rapid progression of symptoms and evidence of respiratory distress (correct)
  • What are the clinical features of anaphylaxis?

    <p>Urticaria, oedema, and cyanosis</p> Signup and view all the answers

    Which condition is NOT a mimic of anaphylaxis?

    <p>Migraine</p> Signup and view all the answers

    What type of hypersensitivity reaction is anaphylaxis?

    <p>Type I IgE-mediated hypersensitivity reaction</p> Signup and view all the answers

    What dosage of adrenaline should be injected intramuscularly in the mid-outer thigh for children?

    <p>0.01 mg/kg</p> Signup and view all the answers

    What is the first and most important therapy in anaphylaxis?

    <p>Adrenaline (epinephrine)</p> Signup and view all the answers

    What should be given if there are signs of poor perfusion and symptoms are not responding to adrenaline injections?

    <p>Normal saline rapid bolus</p> Signup and view all the answers

    When should epinephrine be repeated if there is no response or the response is inadequate?

    <p>Every 5 to 15 minutes</p> Signup and view all the answers

    What should be given if still hypotensive after initial treatment and admission to ICU is needed?

    <p>Aminophylline and nebulized salbutamol</p> Signup and view all the answers

    What is the maximum recommended dose of adrenaline for large children (>50 kg) when injected intramuscularly?

    <p>0.5 mg per dose</p> Signup and view all the answers

    What should be monitored after suspected anaphylaxis in adults?

    <p>Serum tryptase 1–6h after suspected anaphylaxis</p> Signup and view all the answers

    What can help identify allergens to avoid in adults?

    <p>Skin-prick tests showing specific IgE</p> Signup and view all the answers

    What should be done after suspected anaphylaxis to prevent a fatal attack in adults?

    <p>.3mg Epipen® self-injected adrenaline</p> Signup and view all the answers

    What is the first and most important therapy in anaphylaxis in pediatric patients?

    <p>IM epinephrine injection</p> Signup and view all the answers

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