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Anaerobic Respiration and Lactate Metabolism

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Anaerobic Respiration and Lactate Metabolism

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Questions and Answers

Which enzyme is involved in the rate-limiting step of glycolysis?

Glyceraldehyde-3-P dehydrogenase

Hexokinase

Phosphoglycerate kinase

PFK-1 (correct)

What is the role of citrate in regulating glycolysis?

Activates PFK-1

Enhances pyruvate kinase activity

Promotes gluconeogenesis

Inhibits PFK-1 (correct)

What effect does high ATP levels have on glycolysis?

Inhibits PFK-1 (correct)

Activates PFK-1

Promotes F-2,6-BP levels

Stimulates gluconeogenesis

Which molecule captures energy released during the breakdown and stores it in NADH?

Glyceraldehyde-3-P Signup and view all the answers

Which hormone promotes F-2,6-BP levels and stimulates glycolysis?

Insulin Signup and view all the answers

'Phosphorylation of glucose' in glycolysis leads to:

Formation of G-6-P Signup and view all the answers

What is the main purpose of lactate fermentation in cells?

To regenerate NAD+ to allow glycolysis to continue Signup and view all the answers

Which enzyme is responsible for catalyzing the conversion of pyruvate to lactate in lactate fermentation?

Lactate dehydrogenase Signup and view all the answers

What is the consequence of the reduction of two molecules of pyruvate to two molecules of lactate during lactate fermentation?

Reoxidation of NAD+ to NADH Signup and view all the answers

What is the importance of NAD+ regeneration in lactate fermentation?

Essential for glycolysis to continue functioning Signup and view all the answers

In which scenario would cells most likely resort to lactate fermentation?

In hypoxic conditions where oxygen is scarce Signup and view all the answers

What effect does the production of lactate have on cellular pH?

Slightly decreases cellular pH Signup and view all the answers