Podcast
Questions and Answers
Which of the following best describes the primary mechanism of action of teriparatide in treating osteoporosis?
Which of the following best describes the primary mechanism of action of teriparatide in treating osteoporosis?
- Stimulating osteoblast activity to promote new bone formation. (correct)
- Increasing calcium absorption in the small intestine.
- Inhibiting osteoclast activity to reduce bone resorption.
- Reducing inflammation in the joints to alleviate pain and improve mobility.
A client prescribed teriparatide reports experiencing persistent nausea and vomiting. Which of the following is the most appropriate initial nursing action?
A client prescribed teriparatide reports experiencing persistent nausea and vomiting. Which of the following is the most appropriate initial nursing action?
- Assess the client for other signs and symptoms of hypercalcemia. (correct)
- Instruct the client to increase their fluid intake.
- Immediately discontinue the teriparatide injection.
- Administer an antiemetic medication as needed.
A client with a history of renal calculi is being considered for teriparatide therapy. What is the most important consideration before initiating treatment?
A client with a history of renal calculi is being considered for teriparatide therapy. What is the most important consideration before initiating treatment?
- Ruling out any current conditions that increase the risk of hypercalcemia. (correct)
- Monitoring the client's blood pressure closely for hypertension.
- Prescribing a prophylactic medication to prevent renal calculi formation.
- Ensuring the client maintains adequate hydration throughout therapy.
A client on digoxin therapy is prescribed teriparatide. Which electrolyte imbalance should the nurse monitor for, that could increase the risk of digoxin toxicity?
A client on digoxin therapy is prescribed teriparatide. Which electrolyte imbalance should the nurse monitor for, that could increase the risk of digoxin toxicity?
A client taking teriparatide reports feeling dizzy upon standing. What should the nurse advise the client to do?
A client taking teriparatide reports feeling dizzy upon standing. What should the nurse advise the client to do?
If a client misses their daily teriparatide injection, what is the correct course of action?
If a client misses their daily teriparatide injection, what is the correct course of action?
A client is prescribed romosozumab for osteoporosis after not responding well to other treatments. What distinguishes romosozumab from teriparatide and abaloparatide?
A client is prescribed romosozumab for osteoporosis after not responding well to other treatments. What distinguishes romosozumab from teriparatide and abaloparatide?
A client has been using an injection pen for teriparatide for 30 days. What instruction should the nurse provide regarding the pen?
A client has been using an injection pen for teriparatide for 30 days. What instruction should the nurse provide regarding the pen?
Flashcards
Anabolic Agents
Anabolic Agents
Medications that stimulate new bone formation, used to treat osteoporosis.
Teriparatide
Teriparatide
A synthetic form of parathyroid hormone that increases osteoblast activity.
Teriparatide's Action
Teriparatide's Action
Increases number & survival of osteoblasts, making bone formation exceed resorption.
Teriparatide Side Effects
Teriparatide Side Effects
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Monitoring Teriparatide
Monitoring Teriparatide
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Teriparatide Administration
Teriparatide Administration
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Teriparatide Contraindications
Teriparatide Contraindications
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Teriparatide & Digoxin
Teriparatide & Digoxin
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Study Notes
- Anabolic agents treat osteoporosis by stimulating new bone formation.
- Teriparatide is the prototype anabolic agent.
Medication Classification
- Parathyroid agent
Other Anabolic Agents
- Abaloparatide
- Romosozumab, generally for clients who haven't responded to or tolerated other medications
Pharmacologic Action of Teriparatide
- Synthetic parathyroid hormone regulates calcium homeostasis.
- Mediates pathways increasing osteoblast number and survival.
- Bone formation rate exceeds bone resorption.
Adverse Effects
- Hypertension
- Orthostatic hypotension
- Arthralgia
- Leg cramps
- Upper respiratory infections
- Angina
- Hypercalcemia
Interventions
- Monitor serum calcium before and one month after starting therapy, with follow-up based on calcium levels.
- Monitor for toxicity signs like nausea, vomiting, and orthostatic hypotension.
Safety Alert Regarding Hypercalcemia
- Mild, temporary hypercalcemia can occur.
- Reduce dosage or discontinue medication if persistent hypercalcemia occurs.
Administration
- Teriparatide 20 mcg administered subcutaneously once daily.
- Inject when missed dose is remembered that day.
Client Instructions
- Inject into the abdomen or thigh.
- Use an injection pen for 28 days, then discard.
Contraindications and Precautions
- Use cautiously in clients with renal calculi history and hypercalcemia risks due to hypercalcemia risk.
- Avoid in clients with osteosarcoma history and during pregnancy.
Interactions
- Hypercalcemia from teriparatide increases digoxin toxicity risk if taking digoxin.
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Description
Anabolic agents like teriparatide stimulate bone formation to treat osteoporosis. Teriparatide, a synthetic parathyroid hormone, increases osteoblast number. Nurses should monitor calcium levels and watch for adverse effects like hypercalcemia and orthostatic hypotension.
