Podcast
Questions and Answers
Which adverse effects are commonly associated with a fixed-dose combination of agents used to improve symptoms and survival in black patients with HFrEF?
Which adverse effects are commonly associated with a fixed-dose combination of agents used to improve symptoms and survival in black patients with HFrEF?
- Insomnia, anxiety, palpitations
- Joint pain, muscle weakness, fatigue
- Nausea, vomiting, diarrhea
- Headache, dizziness, hypotension (correct)
Why are positive inotropic agents used in heart failure with reduced ejection fraction (HFrEF) controversial?
Why are positive inotropic agents used in heart failure with reduced ejection fraction (HFrEF) controversial?
- They improve survival in HFrEF
- They decrease cardiac output
- They increase intracellular calcium concentration (correct)
- They have no impact on cardiac contractility
Which drug is the only available agent among the digitalis glycosides group?
Which drug is the only available agent among the digitalis glycosides group?
- Digoxin (correct)
- Enalapril
- Lisinopril
- Hydralazine
What is the main pharmacological target of angiotensin receptor blockers (ARBs)?
What is the main pharmacological target of angiotensin receptor blockers (ARBs)?
What is the primary therapeutic use of ACE inhibitors in heart failure treatment?
What is the primary therapeutic use of ACE inhibitors in heart failure treatment?
Which adverse effect is rarely associated with hydralazine use?
Which adverse effect is rarely associated with hydralazine use?
Why are positive inotropic agents generally used for only a short period in patients with heart failure with reduced ejection fraction (HFrEF)?
Why are positive inotropic agents generally used for only a short period in patients with heart failure with reduced ejection fraction (HFrEF)?
What is the term used to describe heart failure with reduced ejection fraction (HFrEF) resulting from the ventricle being unable to pump effectively?
What is the term used to describe heart failure with reduced ejection fraction (HFrEF) resulting from the ventricle being unable to pump effectively?
Which of the following is a direct detrimental effect on cardiac muscle caused by high levels of angiotensin II and aldosterone?
Which of the following is a direct detrimental effect on cardiac muscle caused by high levels of angiotensin II and aldosterone?
What is the main role of natriuretic peptides in heart failure?
What is the main role of natriuretic peptides in heart failure?
Which therapeutic strategy aims to reduce myocardial fibrosis and improve cardiac function in heart failure?
Which therapeutic strategy aims to reduce myocardial fibrosis and improve cardiac function in heart failure?
What is the term applied when the ability of the ventricles to relax and accept blood is impaired by structural changes such as hypertrophy?
What is the term applied when the ability of the ventricles to relax and accept blood is impaired by structural changes such as hypertrophy?
How does excessive elongation of heart muscle fibers affect contractions in heart failure?
How does excessive elongation of heart muscle fibers affect contractions in heart failure?
Which hormone's release is inhibited as a beneficial response to the activation of natriuretic peptides in heart failure?
Which hormone's release is inhibited as a beneficial response to the activation of natriuretic peptides in heart failure?
