Adverse Effects and Complications of Lipid-Soluble Drugs

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14 Questions

What is a common cause of postoperative admission to the intensive care unit?

Respiratory depression

In which patient populations is the risk of respiratory depression high?

Elderly, obese, and those with obstructive sleep apnea

What can occur due to volatile agents and muscle relaxants, though relatively rare?

Dysrhythmias

What leads to decreased peripheral chemoreceptor response to carbon dioxide?

Respiratory depression

Which patient group usually tolerates mild to moderate hypertension well without adverse effects?

Young patients with no symptomatic cardiac disease

Who are at a higher risk of hypotension according to the text?

Hypovolemic patients

What is a concern in patients with coronary artery disease in relation to hypotension caused by general anesthetic drugs?

Reduced end-organ perfusion

Why is it important to document the agent and reaction in case of allergic responses to anesthetic agents?

To clarify reactions and prevent future avoidance

What is a characteristic feature of specific immunoglobulin E-mediated allergic reactions to anesthetic agents?

Shortness of breath

How can a drug be falsely labeled as allergic when it is not?

Due to non-specific cause and effect relationships with adverse events

What is a potential consequence of a high sympathetic tone in response to a surgical stimulus?

Encouragement of dysrhythmias

Why are vasoconstrictor agents contraindicated in correcting hypotension during general anesthesia?

They inhibit surgical site hemostasis

What is a common complication after general anesthesia with an incidence rate of 20-30%?

Postoperative nausea and vomiting (PONV)

Postoperative nausea and vomiting is distressing for approximately what percentage of patients after general anesthesia?

~75%

Learn about the common occurrence of respiratory depression in patients taking lipid-soluble drugs that rapidly cross the blood-brain barrier. Understand how this can lead to decreased central respiratory drive and increased risk of complications like gastric contents aspiration. Explore the varying incidence of respiratory depression based on patient populations and ASA status.

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