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Questions and Answers
What is a probable consequence of hypoventilation caused by opioids?
What is a probable consequence of hypoventilation caused by opioids?
- Hypercapnia and decreased CBF
- Hypercapnia and increased CBF (correct)
- Hypocapnia and increased CBF
- Hypocapnia and decreased CBF
What is the mechanism by which opioids cause miosis?
What is the mechanism by which opioids cause miosis?
- Inhibition of the Edinger-Westphal nucleus in the oculomotor nerve
- Blockade of the pupil constrictor muscle
- Release of histamine in the anterior chamber
- Stimulation of the Edinger-Westphal nucleus in the oculomotor nerve (correct)
Which of the following opioids is contraindicated in patients with impaired renal function?
Which of the following opioids is contraindicated in patients with impaired renal function?
- Fentanyl
- Morphine
- Sufentanil (correct)
- Alfentanil
What is the primary mechanism by which opioids cause nausea and vomiting?
What is the primary mechanism by which opioids cause nausea and vomiting?
Which of the following opioids is associated with a higher risk of biliary smooth muscle spasm?
Which of the following opioids is associated with a higher risk of biliary smooth muscle spasm?
What is the treatment for opioid overdose?
What is the treatment for opioid overdose?
What is the effect of increasing concentration of volatile anesthetics on spontaneously breathing patients' respirations?
What is the effect of increasing concentration of volatile anesthetics on spontaneously breathing patients' respirations?
What is the effect of cardiovascular depression on the rate of rise of FA/FI?
What is the effect of cardiovascular depression on the rate of rise of FA/FI?
What is the effect of right-to-left shunt on the induction of anesthesia?
What is the effect of right-to-left shunt on the induction of anesthesia?
What is the primary mechanism of biotransformation of inhalation anesthetics?
What is the primary mechanism of biotransformation of inhalation anesthetics?
What is the primary mechanism of opioid-induced ventilatory depression?
What is the primary mechanism of opioid-induced ventilatory depression?
What is the effect of opioid-induced histamine release on cardiovascular function?
What is the effect of opioid-induced histamine release on cardiovascular function?
What is the effect of opioid-induced cough suppression on medullary cough centers?
What is the effect of opioid-induced cough suppression on medullary cough centers?
What is the primary mechanism of opioid-induced CNS effects?
What is the primary mechanism of opioid-induced CNS effects?
What is the effect of woodene chest syndrome on laryngeal musculature?
What is the effect of woodene chest syndrome on laryngeal musculature?
What is the effect of nitrous oxide washout on alveolar partial pressures of oxygen?
What is the effect of nitrous oxide washout on alveolar partial pressures of oxygen?
What is the primary reason for the rapid decrease in plasma concentration of morphine?
What is the primary reason for the rapid decrease in plasma concentration of morphine?
Which opioid is associated with an increased risk of acute dystonia in untreated Parkinson's disease?
Which opioid is associated with an increased risk of acute dystonia in untreated Parkinson's disease?
What is the mechanism of pain modulation by nerve stimulators?
What is the mechanism of pain modulation by nerve stimulators?
What is the primary mechanism of opioid tolerance?
What is the primary mechanism of opioid tolerance?
Which opioid has the highest elimination half-time?
Which opioid has the highest elimination half-time?
What is the effect of benzos and fentanyl on GA?
What is the effect of benzos and fentanyl on GA?
What is the primary conjugation reaction of morphine in the liver?
What is the primary conjugation reaction of morphine in the liver?
What is the primary site of pain perception?
What is the primary site of pain perception?
What is the primary benefit of regional anesthesia?
What is the primary benefit of regional anesthesia?
What is the decrease in MAC per decade from 1 year of age onward?
What is the decrease in MAC per decade from 1 year of age onward?
What is the primary factor affecting the onset, duration, and potency of local anesthetics?
What is the primary factor affecting the onset, duration, and potency of local anesthetics?
Which evoked potential is the most sensitive?
Which evoked potential is the most sensitive?
What is the NIOSH-set exposure limit for volatile anesthetics?
What is the NIOSH-set exposure limit for volatile anesthetics?
What is the effect of nitrous oxide on methionine synthetase?
What is the effect of nitrous oxide on methionine synthetase?
What is the most likely place to have a leak in an anesthesia machine?
What is the most likely place to have a leak in an anesthesia machine?
What is the effect of morphine on vagal nuclei in medulla?
What is the effect of morphine on vagal nuclei in medulla?
What is the primary mechanism by which malignant hyperthermia affects muscle function?
What is the primary mechanism by which malignant hyperthermia affects muscle function?
What is the recommended observation period for a patient with masseter spasm following succinylcholine administration?
What is the recommended observation period for a patient with masseter spasm following succinylcholine administration?
What is the primary reason for the increased incidence of malignant hyperthermia when succinylcholine is used with volatile anesthetics?
What is the primary reason for the increased incidence of malignant hyperthermia when succinylcholine is used with volatile anesthetics?
What is the primary mechanism of metabolism for atracurium?
What is the primary mechanism of metabolism for atracurium?
What is the primary cause of cardiac side effects seen with high doses of atracurium?
What is the primary cause of cardiac side effects seen with high doses of atracurium?
What is the effect of administering anticholinesterase drugs, such as neostigmine, prior to succinylcholine?
What is the effect of administering anticholinesterase drugs, such as neostigmine, prior to succinylcholine?
What is the primary reason for the additive, not independent or synergistic nature of local anesthetics' toxicities?
What is the primary reason for the additive, not independent or synergistic nature of local anesthetics' toxicities?
What is the effect of PH adjustment on the onset of local anesthetic block?
What is the effect of PH adjustment on the onset of local anesthetic block?
Why are spinal nerves and nerve roots more susceptible to local anesthetic-induced toxicity?
Why are spinal nerves and nerve roots more susceptible to local anesthetic-induced toxicity?
What is the primary mechanism of methemoglobinemia induced by topical administration of local anesthetics?
What is the primary mechanism of methemoglobinemia induced by topical administration of local anesthetics?
What is the primary reason for the increased cardiovascular toxicity of bupivacaine?
What is the primary reason for the increased cardiovascular toxicity of bupivacaine?
What is the primary treatment for local anesthetic systemic toxicity (LAST)?
What is the primary treatment for local anesthetic systemic toxicity (LAST)?
What is the primary mechanism by which non-depolarizing NMBs exert their effect?
What is the primary mechanism by which non-depolarizing NMBs exert their effect?
What is the primary reason for the contraindication of succinylcholine in otherwise healthy children?
What is the primary reason for the contraindication of succinylcholine in otherwise healthy children?
What is the purpose of pairing an anticholinesterase with an antimuscarinic for reversal of neuromuscular blockade?
What is the purpose of pairing an anticholinesterase with an antimuscarinic for reversal of neuromuscular blockade?
What is the effect of volatile anesthetics on non-depolarizing NMBs?
What is the effect of volatile anesthetics on non-depolarizing NMBs?
What is the significance of fade on TOF monitoring in non-depolarizing NMBs?
What is the significance of fade on TOF monitoring in non-depolarizing NMBs?
What is the significance of clinical assessment of recovery from NM blockade?
What is the significance of clinical assessment of recovery from NM blockade?
What is the primary determinant of the rate of rise of FA/FI?
What is the primary determinant of the rate of rise of FA/FI?
What is the effect of increasing cardiac output on the rate of rise of FA/FI?
What is the effect of increasing cardiac output on the rate of rise of FA/FI?
What is the primary mechanism by which the second gas effect accelerates the rate of rise of FA/FI?
What is the primary mechanism by which the second gas effect accelerates the rate of rise of FA/FI?
What is the effect of decreasing the FRC on the rate of rise of FA/FI?
What is the effect of decreasing the FRC on the rate of rise of FA/FI?
What is the primary reason why pediatric inhalation induction is faster than adults?
What is the primary reason why pediatric inhalation induction is faster than adults?
What is the effect of increasing the inspired concentration of the anesthetic on the rate of rise of FA/FI?
What is the effect of increasing the inspired concentration of the anesthetic on the rate of rise of FA/FI?
What is the primary mechanism by which the concentration effect accelerates the rate of rise of FA/FI?
What is the primary mechanism by which the concentration effect accelerates the rate of rise of FA/FI?
What is the effect of a competitive antagonist on the potency and efficacy of an agonist?
What is the effect of a competitive antagonist on the potency and efficacy of an agonist?
What is the effect of decreasing the solubility of the anesthetic in blood on the rate of rise of FA/FI?
What is the effect of decreasing the solubility of the anesthetic in blood on the rate of rise of FA/FI?
What is the primary mechanism of termination of action of a bolus dose of an induction agent?
What is the primary mechanism of termination of action of a bolus dose of an induction agent?
What is the primary mechanism by which the alveolar to mixed venous partial pressure difference affects the rate of rise of FA/FI?
What is the primary mechanism by which the alveolar to mixed venous partial pressure difference affects the rate of rise of FA/FI?
What is the meaning of pKa in the context of weak acids and bases?
What is the meaning of pKa in the context of weak acids and bases?
What is the volume of distribution (Vd) of a drug?
What is the volume of distribution (Vd) of a drug?
What is the effect of increasing the fresh gas flow on the rate of rise of FA/FI?
What is the effect of increasing the fresh gas flow on the rate of rise of FA/FI?
What is the meaning of the term 'high extraction ratio' (HER) in pharmacokinetics?
What is the meaning of the term 'high extraction ratio' (HER) in pharmacokinetics?
What is the primary mechanism of action of propofol?
What is the primary mechanism of action of propofol?
What is the recommended observation period for a patient with masseter spasm following succinylcholine administration?
What is the recommended observation period for a patient with masseter spasm following succinylcholine administration?
What is the primary mechanism of hepatic clearance of a drug?
What is the primary mechanism of hepatic clearance of a drug?
What is the primary mechanism of action of non-competitive antagonists?
What is the primary mechanism of action of non-competitive antagonists?
What is the primary factor affecting the onset, duration, and potency of local anesthetics?
What is the primary factor affecting the onset, duration, and potency of local anesthetics?
What is the primary mechanism by which malignant hyperthermia affects muscle function?
What is the primary mechanism by which malignant hyperthermia affects muscle function?
What is the formula for creatinine clearance (ml/min)?
What is the formula for creatinine clearance (ml/min)?
What is the effect of adding succinylcholine to volatile anesthetics?
What is the effect of adding succinylcholine to volatile anesthetics?
What is the primary reason for the increased duration of succinylcholine-induced neuromuscular blockade after administering an anticholinesterase drug?
What is the primary reason for the increased duration of succinylcholine-induced neuromuscular blockade after administering an anticholinesterase drug?
What is the primary mechanism of atracurium metabolism?
What is the primary mechanism of atracurium metabolism?
What is the cardiovascular side effect seen with high doses of atracurium?
What is the cardiovascular side effect seen with high doses of atracurium?
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