Adverse Drug Reactions and Lactation Quiz

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Questions and Answers

Which of the following adverse drug reactions (ADRs) is NOT associated with vasoconstriction of peripheral blood vessels?

  • Diarrhea (correct)
  • Nausea
  • Gangrene
  • Hypertension

What is one of the indications for drug use in the induction of labor?

  • Hypertension management
  • Treatment of gangrene
  • Vasoconstriction of peripheral blood vessels
  • Induction in the 1st and 2nd stages of labor (correct)

Which ADR is often associated with significant vascular complications?

  • Nausea
  • Gangrene (correct)
  • Diarrhea
  • Hypertension

Which of the following conditions is indicated as a possible adverse effect of certain drugs on the peripheral blood vessels?

<p>Vasoconstriction (D)</p> Signup and view all the answers

Which adverse drug reaction could potentially lead to tissue death if blood flow is severely compromised?

<p>Gangrene (B)</p> Signup and view all the answers

What role do myoepithelial cells play in the process of lactation?

<p>They contract to aid in milk ejection. (B)</p> Signup and view all the answers

What hormone is responsible for contracting myoepithelial cells during lactation?

<p>Oxytocin (C)</p> Signup and view all the answers

Which of the following best describes the effect of oxytocin on myoepithelial cells?

<p>It contracts them to promote milk ejection. (D)</p> Signup and view all the answers

How do myoepithelial cells contribute to the breastfeeding process?

<p>They assist in the smooth flow of milk by contracting. (D)</p> Signup and view all the answers

During nursing, what physiological mechanism is triggered by oxytocin regarding myoepithelial cells?

<p>Contraction for milk release. (C)</p> Signup and view all the answers

What is the primary effect of oxytocin when it interacts with the membrane receptors of uterine muscle cells?

<p>Increases cytoplasmic calcium levels (C)</p> Signup and view all the answers

Which of the following statements about oxytocin is true?

<p>It is not bound to plasma proteins. (B)</p> Signup and view all the answers

How is oxytocin primarily administered to achieve its effects?

<p>Intravenously (D)</p> Signup and view all the answers

What happens to oxytocin if taken orally?

<p>It is destroyed in the gastrointestinal tract. (D)</p> Signup and view all the answers

What is a key result of increased cytoplasmic calcium in uterine muscle cells?

<p>Stimulation of uterine contraction (B)</p> Signup and view all the answers

What type of contractions does oxytocin produce during labor?

<p>Normal physiological contractions (D)</p> Signup and view all the answers

In which situation is ergometrine exclusively used?

<p>Management of postpartum hemorrhage (D)</p> Signup and view all the answers

Which statement accurately describes the use of oxytocin?

<p>Used to induce and augment labor (D)</p> Signup and view all the answers

How do the contractions produced by ergometrine differ from those produced by oxytocin?

<p>They do not resemble normal physiological contractions (B)</p> Signup and view all the answers

Which of the following is NOT a characteristic of oxytocin?

<p>Used solely for postpartum hemorrhage (D)</p> Signup and view all the answers

Which prostaglandin is used as a vaginal suppository?

<p>PGE2 - Dinoprostone (D)</p> Signup and view all the answers

What is the primary use of Prostaglandins in the context provided?

<p>Induction of labor and abortion (A)</p> Signup and view all the answers

Which of the following is a contraindication of using Prostaglandins?

<p>Mechanical obstruction of delivery (D)</p> Signup and view all the answers

Which drug is a selective beta-2 receptor agonist used specifically as a uterine relaxant?

<p>Ritodrine (A)</p> Signup and view all the answers

What is a known side effect of Misoprostol?

<p>Nausea and vomiting (B)</p> Signup and view all the answers

Calcium channel blockers like Nifedipine are primarily used to:

<p>Relax the uterus (B)</p> Signup and view all the answers

What mechanism of action do β-adrenoceptor agonists utilize to relax the uterus?

<p>Activation of adenylate cyclase to increase cAMP (D)</p> Signup and view all the answers

Which of the following is NOT a contraindication for Prostaglandins?

<p>Normal pregnancy (A)</p> Signup and view all the answers

What effect do Tocolytic drugs have on pregnancy?

<p>Arrest threatened abortion or delay premature labor (D)</p> Signup and view all the answers

Which side effect is associated specifically with PGF2α?

<p>Bronchospasm (B)</p> Signup and view all the answers

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