Adverse Drug Reactions and Lactation Quiz
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Questions and Answers

Which of the following adverse drug reactions (ADRs) is NOT associated with vasoconstriction of peripheral blood vessels?

  • Diarrhea (correct)
  • Nausea
  • Gangrene
  • Hypertension
  • What is one of the indications for drug use in the induction of labor?

  • Hypertension management
  • Treatment of gangrene
  • Vasoconstriction of peripheral blood vessels
  • Induction in the 1st and 2nd stages of labor (correct)
  • Which ADR is often associated with significant vascular complications?

  • Nausea
  • Gangrene (correct)
  • Diarrhea
  • Hypertension
  • Which of the following conditions is indicated as a possible adverse effect of certain drugs on the peripheral blood vessels?

    <p>Vasoconstriction</p> Signup and view all the answers

    Which adverse drug reaction could potentially lead to tissue death if blood flow is severely compromised?

    <p>Gangrene</p> Signup and view all the answers

    What role do myoepithelial cells play in the process of lactation?

    <p>They contract to aid in milk ejection.</p> Signup and view all the answers

    What hormone is responsible for contracting myoepithelial cells during lactation?

    <p>Oxytocin</p> Signup and view all the answers

    Which of the following best describes the effect of oxytocin on myoepithelial cells?

    <p>It contracts them to promote milk ejection.</p> Signup and view all the answers

    How do myoepithelial cells contribute to the breastfeeding process?

    <p>They assist in the smooth flow of milk by contracting.</p> Signup and view all the answers

    During nursing, what physiological mechanism is triggered by oxytocin regarding myoepithelial cells?

    <p>Contraction for milk release.</p> Signup and view all the answers

    What is the primary effect of oxytocin when it interacts with the membrane receptors of uterine muscle cells?

    <p>Increases cytoplasmic calcium levels</p> Signup and view all the answers

    Which of the following statements about oxytocin is true?

    <p>It is not bound to plasma proteins.</p> Signup and view all the answers

    How is oxytocin primarily administered to achieve its effects?

    <p>Intravenously</p> Signup and view all the answers

    What happens to oxytocin if taken orally?

    <p>It is destroyed in the gastrointestinal tract.</p> Signup and view all the answers

    What is a key result of increased cytoplasmic calcium in uterine muscle cells?

    <p>Stimulation of uterine contraction</p> Signup and view all the answers

    What type of contractions does oxytocin produce during labor?

    <p>Normal physiological contractions</p> Signup and view all the answers

    In which situation is ergometrine exclusively used?

    <p>Management of postpartum hemorrhage</p> Signup and view all the answers

    Which statement accurately describes the use of oxytocin?

    <p>Used to induce and augment labor</p> Signup and view all the answers

    How do the contractions produced by ergometrine differ from those produced by oxytocin?

    <p>They do not resemble normal physiological contractions</p> Signup and view all the answers

    Which of the following is NOT a characteristic of oxytocin?

    <p>Used solely for postpartum hemorrhage</p> Signup and view all the answers

    Which prostaglandin is used as a vaginal suppository?

    <p>PGE2 - Dinoprostone</p> Signup and view all the answers

    What is the primary use of Prostaglandins in the context provided?

    <p>Induction of labor and abortion</p> Signup and view all the answers

    Which of the following is a contraindication of using Prostaglandins?

    <p>Mechanical obstruction of delivery</p> Signup and view all the answers

    Which drug is a selective beta-2 receptor agonist used specifically as a uterine relaxant?

    <p>Ritodrine</p> Signup and view all the answers

    What is a known side effect of Misoprostol?

    <p>Nausea and vomiting</p> Signup and view all the answers

    Calcium channel blockers like Nifedipine are primarily used to:

    <p>Relax the uterus</p> Signup and view all the answers

    What mechanism of action do β-adrenoceptor agonists utilize to relax the uterus?

    <p>Activation of adenylate cyclase to increase cAMP</p> Signup and view all the answers

    Which of the following is NOT a contraindication for Prostaglandins?

    <p>Normal pregnancy</p> Signup and view all the answers

    What effect do Tocolytic drugs have on pregnancy?

    <p>Arrest threatened abortion or delay premature labor</p> Signup and view all the answers

    Which side effect is associated specifically with PGF2α?

    <p>Bronchospasm</p> Signup and view all the answers

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