29 Questions
What is the primary purpose of ACTH?
Regulating glucose, protein, and lipid metabolism
Which gland produces ACTH?
Pituitary gland
What hormone stimulates the production of ACTH by the pituitary gland?
Corticotropin-releasing hormone (CRH)
When do ACTH levels increase?
When cortisol is low
What is the purpose of an ACTH test, usually in conjunction with cortisol tests?
To help detect conditions associated with excessive or deficient cortisol in the body
What can too much cortisol cause?
Obesity and increased body hair
How do patients with insufficient cortisol production typically present?
Muscle weakness and fatigue
When are ACTH and cortisol levels typically at their highest and lowest, respectively?
Both at their highest in the morning
What is the primary purpose of suppression or stimulation testing for ACTH and cortisol?
To evaluate hormone production and function
What are the primary symptoms of hypopituitarism?
Decreased hormone production by the pituitary
What does a decreased level of ACTH indicate in the context of testing for adrenal gland problems?
Hypopituitarism
What is the most common sample used for testing ACTH and cortisol levels?
Fasting blood serum (early morning)
Which hormone stimulates the production of cortisol by the adrenal glands?
Corticotropin-releasing hormone (CRH)
What are the primary functions of cortisol in the body?
Regulating glucose, protein, and lipid metabolism
What conditions can be diagnosed using ACTH blood tests in conjunction with cortisol tests?
Cushing syndrome
What symptoms can be associated with excessive cortisol production?
Obesity and high potassium levels
In which condition is both ACTH and cortisol increased?
Cushing disease (pituitary tumor producing ACTH)
What is the purpose of suppression or stimulation testing for ACTH and cortisol?
To determine the cause of abnormal initial findings
When are ACTH and cortisol levels typically at their highest?
In the morning
What are cardiac biomarkers?
Chemical substances released into the blood when the heart is damaged or stressed
What is the most sensitive biomarker test for detecting heart damage?
Troponin
What is the clinical utility of Aspartate aminotransferase (AST)?
Hepatocellular and skeletal disorders
What is the primary role of myoglobin in the body?
Oxygen binding protein of cardiac and skeletal muscle
Which enzyme accounts for only 3-20% of total CK activity in the heart?
CK-MB (CK-2)
Where is lactate dehydrogenase (LDH) found?
Skeletal muscle, liver, heart, kidney, and red blood cells
What is the composition of cardiac troponins?
Complex of 3 protein subunits
Which enzyme is widely distributed in different tissues and has the highest concentrations in cardiac tissue, liver, and skeletal muscle?
Aspartate aminotransferase (AST)
What is the clinical significance of myoglobin levels in the context of muscle trauma and AMI?
Increased in cardiac muscle trauma, skeletal muscle trauma, and AMI
What is the total sensitivity and specificity of Creatine Kinase (CK or CPK)?
%40 sensitive and %80 specific
Test your knowledge on the functions of adrenocorticotropic hormone (ACTH) and its role in regulating cortisol production. Learn about the influence of ACTH on glucose, protein, and lipid metabolism, immune system suppression, and blood pressure maintenance.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
