Adrenergic Agonists and Their Effects
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Questions and Answers

Why is it important to monitor blood glucose levels in diabetic clients receiving adrenergic agonists?

  • Adrenergic agonists can cause hypoglycemia.
  • Adrenergic agonists can increase blood sugar levels. (correct)
  • Adrenergic agonists can mask the symptoms of hyperglycemia.
  • Adrenergic agonists improve glucose tolerance.

A patient is prescribed an adrenergic agonist. Which instruction is most important to include in the patient's teaching regarding potential adverse effects?

  • Report any instances of increased appetite.
  • Report palpitations or irregular heart rate. (correct)
  • Reduce fluid intake to avoid edema.
  • Monitor for signs of hypoglycemia.

A patient who self-administers an EpiPen should seek immediate medical attention if they need to use the EpiPen how often?

  • More than five times per day.
  • More than twice a week. (correct)
  • More than once a month.
  • More than once a year.

Why should patients be advised to avoid using nasal sprays containing adrenergic agonists for longer than 3-5 days?

<p>To minimize the risk of rebound congestion. (A)</p> Signup and view all the answers

When administering an adrenergic agonist intravenously, what is the primary nursing intervention to ensure patient safety?

<p>Monitor the IV site for signs of infiltration. (B)</p> Signup and view all the answers

Which physiological response is primarily associated with the stimulation of alpha 1 adrenergic receptors?

<p>Vasoconstriction (B)</p> Signup and view all the answers

A patient is experiencing a severe allergic reaction with bronchospasm. Which adrenergic agonist is most appropriate for this situation?

<p>Epinephrine (B)</p> Signup and view all the answers

What is the primary effect of beta 2 adrenergic receptor stimulation on the uterus?

<p>Relaxation of smooth muscles (D)</p> Signup and view all the answers

A patient with a history of hypertension is prescribed an adrenergic agonist. What potential side effect requires close monitoring?

<p>Tachycardia (D)</p> Signup and view all the answers

What is the expected effect of epinephrine on blood sugar levels, and through which receptor does it primarily act to cause this effect?

<p>Increases blood sugar via beta 2 receptors (A)</p> Signup and view all the answers

Why should epinephrine be used with caution in patients with diabetes mellitus?

<p>It promotes hyperglycemia. (A)</p> Signup and view all the answers

A patient taking a nonselective beta blocker is given epinephrine for anaphylaxis. What potential drug interaction should be considered?

<p>Blocked epinephrine effects (C)</p> Signup and view all the answers

What is a contraindication for the administration of epinephrine?

<p>Glaucoma (C)</p> Signup and view all the answers

Flashcards

Adrenergic Agonists Function

Stimulates the sympathetic nervous system, mimicking norepinephrine and epinephrine.

Alpha 1 Receptor Effects

Increases cardiac contractility and vasoconstriction; dilates pupils, relaxes the bladder, contracts the prostate.

Beta 1 Receptor Effects

Increases heart rate and contractility, increases renin secretion and blood pressure.

Beta 2 Receptor Effects

Causes bronchodilation, decreases GI tone and motility, increases blood flow in skeletal muscles, relaxes uterine smooth muscle, and increases blood sugar.

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Epinephrine Action

Nonselective adrenergic agonist stimulating alpha 1, beta 1, and beta 2 receptors.

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Epinephrine Uses

Anaphylaxis, bronchospasms, cardiogenic shock and cardiac arrest

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Epinephrine Side Effects

GI disturbances, sweating, headache, insomnia, hyperglycemia, palpitations, dysrhythmia, tachycardia, and hypertension.

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Epinephrine Contraindications

Tachycardia and Glaucoma

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Adrenergic agonists and blood sugar

Adrenergic agonists can elevate blood sugar levels

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Adrenergic agonist monitoring

Monitor BP, HR, urine output; watch IV site for infiltration; cardiac monitoring if IV; report hypertension, irregular HR or tachycardia

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Adrenergic agonist precautions

Report palpitations and avoid drugs that increase blood pressure (cold meds, diet pills); avoid when breastfeeding; limit nasal sprays to 3-5 days.

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EpiPen usage

Carry at all times, inject in outer thigh at first sign of reaction, don't refrigerate, inspect for discoloration, massage site after injection, report side effects.

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Adrenergic agonist evaluation

Evaluate for symptom improvement, side effects, adverse reactions, and understanding of medication use.

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Study Notes

Adrenergic Agonists

  • They stimulate the sympathetic nervous system.
  • They mimic the neurotransmitters norepinephrine and epinephrine.
  • They act on adrenergic receptor sites in the heart, bronchi, GI tract, urinary bladder, and ciliary eye muscles.

Effects of Adrenergic Agonists at Receptors

Alpha 1

  • Increases cardiac contractility and vasoconstriction
  • Dilates pupils
  • Relaxes the bladder.
  • Contracts the prostate

Beta 1

  • Increases cardiac contractility and heart rate
  • Increases renin secretion and blood pressure
  • Affects the heart

Beta 2

  • Decreases GI tone and motility
  • Causes bronchodilation
  • Increases blood flow in skeletal muscles
  • Relaxes smooth muscles of the uterus
  • Activates liver glycogenolysis, which increases blood sugar
  • Mainly affects the lungs

Adrenergic Agonist - Epinephrine

  • It is a nonselective drug that stimulates alpha 1, beta 1, and beta 2 receptors.
  • It activates the sympathetic nervous system.
  • Alpha 1 increases blood pressure.
  • Beta 1 increases the heart rate.
  • Beta 2 promotes bronchodilation.

Uses of Epinephrine

  • Anaphylaxis and anaphylactic shock
  • Bronchospasms and status asthmaticus
  • Cardiogenic shock and cardiac arrest

Side Effects/Adverse Reactions of Epinephrine

  • GI disturbances
  • Sweating, headache, insomnia, dizziness, agitation, and anxiety
  • Hyperglycemia
  • Palpitations and cardiac dysrhythmia
  • Tachycardia
  • Hypertension

Contraindications of Epinephrine

  • Tachycardia
  • Glaucoma
  • Labor

Cautions for Epinephrine

  • Hypertension
  • Prostatic hypertrophy
  • Diabetes mellitus

Interactions of Epinephrine

  • Monoamine oxidase inhibitors (MAOIs) and tricyclic antidepressants intensify and prolong its effect.
  • Beta blockers block its effect.
  • Digoxin may increase the risk of dysrhythmias.
  • It increases blood sugar.

Adrenergic Agonist Drugs Assessment

  • Assess vital signs.
  • Obtain a medical history.
  • Inquire about current symptoms.
  • Obtain a baseline glucose level.

Adrenergic Agonist Drugs Nursing Interventions

  • Monitor blood pressure, heart rate, and urine output.
  • Monitor IV site for infiltration, administer IV push slowly (1 mg/minute) unless in cardiac arrest.
  • Use a cardiac monitor when giving IV medication.
  • Monitor for side effects/adverse reactions, and report hypertension, irregular heart rate, and tachycardia.
  • Monitor blood glucose in diabetic clients.

Adrenergic Agonist Drugs Teaching

  • Report side effects/adverse reactions like palpitations.
  • Avoid drugs that increase blood pressure such as cold medicine and diet pills.
  • Avoid adrenergics when breastfeeding.
  • Only use nasal sprays for 3-5 days.
  • Take medication as prescribed.
  • How to use inhaled drugs or drops; return demonstration.

Epi-Pen Teaching

  • Inform the provider if the EpiPen is used more than twice a week.
  • Carry the EpiPen at all times.
  • Do not refrigerate the EpiPen; store it in a cool, dark place.
  • Use the EpiPen at the first sign of a reaction.
  • Inspect the contents for particles; do not use if particles are pink or brown.
  • Inject subcutaneously in the outer thigh and hold in place for 5-10 seconds.
  • Massage the injection site after administration.
  • Report side effects/adverse reactions.

Adrenergic Agonist Drugs - Evaluation

  • Evaluate the client's response to medication.
  • Evaluate improvement in symptoms.
  • Assess any side effects/adverse reactions.
  • Determine if the client understands medication and its use.

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Description

Adrenergic agonists stimulate the sympathetic nervous system, mimicking norepinephrine and epinephrine. They act on adrenergic receptors, influencing heart contractility, vasoconstriction, bronchodilation, and blood sugar levels. Epinephrine is a nonselective adrenergic agonist, stimulating alpha 1, beta 1, and beta 2 receptors.

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