Adrenergic Agonists - Nursing Pharmacology PDF

Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonists Unit 4 NUR 210/BSL 101  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonists Function of adrenergic Stimulate sympathetic nervous system Mimic neurotransmitters norepinephrine and epinephrine Act on...

Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonists Unit 4 NUR 210/BSL 101  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonists Function of adrenergic Stimulate sympathetic nervous system Mimic neurotransmitters norepinephrine and epinephrine Act on adrenergic receptor sites: Heart, bronchi, GI tract Urinary bladder, ciliary eye muscles  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonists Function of adrenergics (sympathetic nervous system)  Antihyperlipidemic & Vasodilators - Unit 6 Effects of Adrenergic Agonists at Receptors Alpha 1 Increases cardiac contractility, vasoconstriction Dilates pupils Relaxes the bladder Contracts the prostate  Antihyperlipidemic & Vasodilators - Unit 6 Effects of Adrenergic Agonists at Receptors Beta 1 Increases cardiac contractility, heart rate Increases renin secretion, blood pressure Beta 2 Decreases GI tone and motility Bronchodilation Increases blood flow in skeletal muscles Relaxes smooth muscles of uterus Activates liver glycogenolysis ? increases blood sugar Remember beta 1 ? 1 heart so it mainly affects the heart Beta 2 ? 2 lungs so it mainly affects the lungs  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonist - Epinephrine Epinephrine Nonselective ? stimulates alpha 1, beta 1, and beta 2 Action Activates the sympathetic nervous system. Alpha 1 increases the blood pressure Beta 1 increases the heart rate Beta 2 promotes bronchodilation  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonist - Epinephrine Uses Anaphylaxis, anaphylactic shock Bronchospasms, status asthmaticus Cardiogenic shock, cardiac arrest  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonist - Epinephrine Side effects/Adverse reactions GI disturbances Sweating, headache, insomnia, dizziness, agitation, anxious Hyperglycemia Palpitations, cardiac dysrhythmia Tachycardia Hypertension  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonist - Epinephrine Contraindications Tachycardia Glaucoma Labor Caution Hypertension Prostatic hypertrophy Diabetes mellitus  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonist - Epinephrine Interactions MAOI?s tricyclic antidepressants ? intensify and prolong effect Beta blockers ? block effect Digoxin ? can increase risk of dysrhythmia Lab ? increases blood sugar  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonist Drugs Assessment Assessment Vital signs Medication/medical history Current symptoms Baseline glucose level  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonist Drugs Nursing Interventions Nursing interventions Monitor blood pressure, heart rate and urine output Monitor IV site for infiltration. Give IV push slowly (1 mg/minute) unless in cardiac arrest Client on cardiac monitor when giving IV Monitor for side effects/adverse reactions ? report hypertension, irregular heart rate, tachycardia Monitor blood glucose in diabetic clients  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonist Drugs Teaching Teaching The side effects/adverse reactions to report (palpitations) Avoid drugs that increase the blood pressure such as cold medication and diet pills Avoid adrenergics when breastfeeding Nasal sprays should only be used 3-5 days Take medication as prescribed How to use inhaled drugs or drops ? return demonstration  Antihyperlipidemic & Vasodilators - Unit 6 Epi-Pen Teaching Teaching Inform provider if Epipen is used more than twice a week Have Epipen with you at all times Do not refrigerate Epipen but store in cool, dark place Use Epipen at first sign of reaction Inspect the contents for particles and do not use if particles are pink or brown Inject subcutaneously in the outer thigh and hold in place for 5-10 seconds After administration massage the injection site Report side effects/adverse reactions  Antihyperlipidemic & Vasodilators - Unit 6 Adrenergic Agonist Drugs - Evaluation Evaluation Client?s response to medication Improvement in symptoms? Any side effects/adverse reactions? Client understands medication and use?