Adrenal Cortex Layers and Hormone Secretion Regulation Quiz
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Questions and Answers

Which layer of the adrenal cortex is the principal source of mineralocorticoids?

  • Zona granulosa
  • Zona fasciculata
  • Zona glomerulosa (correct)
  • Zona reticularis

What is the primary site of glucocorticoid synthesis in the adrenal cortex?

  • Zona granulosa
  • Zona reticularis
  • Zona fasciculata (correct)
  • Zona glomerulosa

Which adrenal cortex layer produces weak androgens like androstenedione and dehydroepiandrosterone?

  • Zona reticularis (correct)
  • Zona glomerulosa
  • Zona fasciculata
  • Zona granulosa

Which hormone is the principal glucocorticoid synthesized by the adrenal cortex?

<p>Cortisol (C)</p> Signup and view all the answers

Which of the following hormones inhibits the secretion of ACTH?

<p>Cortisol (D)</p> Signup and view all the answers

When is the highest plasma level of cortisol typically observed?

<p>In the early morning (B)</p> Signup and view all the answers

What type of deficiency can lead to hyponatremia due to increased renal sodium loss?

<p>Mineralocorticoid deficiency (A)</p> Signup and view all the answers

Which enzyme assay is typically used to measure plasma renin concentration (PRC)?

<p>Immunoassay (B)</p> Signup and view all the answers

What is the principal adrenal androgen involved in the production of potent androgens and estrogens?

<p>DHEA (A)</p> Signup and view all the answers

Excessive levels of androgens can lead to what condition?

<p>Virilization (C)</p> Signup and view all the answers

Which hormone is primarily produced by the adrenal medulla?

<p>Epinephrine (C)</p> Signup and view all the answers

What is the precursor of androgens that includes DHEA and DHEA-S?

<p>DHT (B)</p> Signup and view all the answers

What is the best method for PTH measurement?

<p>Using antibodies that detect both the amino-terminal fragment and intact PTH (A)</p> Signup and view all the answers

Why do PTH concentrations differ even when the same generation assay is used?

<p>Due to differences in the detection of PTH fragments by assay-specific antibodies (C)</p> Signup and view all the answers

What is a candidate reference method for PTH assay?

<p>Liquid chromatography with tandem mass spectrometry (LC-MS/MS) (A)</p> Signup and view all the answers

Where is the adrenal medulla located?

<p>Inner region of the adrenal gland (B)</p> Signup and view all the answers

What is the basic structure found in cortical hormones?

<p>Cyclopentanperhydrophenant (CP) ring (C)</p> Signup and view all the answers

What synthesizes cortical hormones from LDL?

<p>Only G cells (D)</p> Signup and view all the answers

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