Adrenal Cortex Layers and Hormone Secretion Regulation Quiz
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Questions and Answers

Which layer of the adrenal cortex is the principal source of mineralocorticoids?

  • Zona granulosa
  • Zona fasciculata
  • Zona glomerulosa (correct)
  • Zona reticularis
  • What is the primary site of glucocorticoid synthesis in the adrenal cortex?

  • Zona granulosa
  • Zona reticularis
  • Zona fasciculata (correct)
  • Zona glomerulosa
  • Which adrenal cortex layer produces weak androgens like androstenedione and dehydroepiandrosterone?

  • Zona reticularis (correct)
  • Zona glomerulosa
  • Zona fasciculata
  • Zona granulosa
  • Which hormone is the principal glucocorticoid synthesized by the adrenal cortex?

    <p>Cortisol</p> Signup and view all the answers

    Which of the following hormones inhibits the secretion of ACTH?

    <p>Cortisol</p> Signup and view all the answers

    When is the highest plasma level of cortisol typically observed?

    <p>In the early morning</p> Signup and view all the answers

    What type of deficiency can lead to hyponatremia due to increased renal sodium loss?

    <p>Mineralocorticoid deficiency</p> Signup and view all the answers

    Which enzyme assay is typically used to measure plasma renin concentration (PRC)?

    <p>Immunoassay</p> Signup and view all the answers

    What is the principal adrenal androgen involved in the production of potent androgens and estrogens?

    <p>DHEA</p> Signup and view all the answers

    Excessive levels of androgens can lead to what condition?

    <p>Virilization</p> Signup and view all the answers

    Which hormone is primarily produced by the adrenal medulla?

    <p>Epinephrine</p> Signup and view all the answers

    What is the precursor of androgens that includes DHEA and DHEA-S?

    <p>DHT</p> Signup and view all the answers

    What is the best method for PTH measurement?

    <p>Using antibodies that detect both the amino-terminal fragment and intact PTH</p> Signup and view all the answers

    Why do PTH concentrations differ even when the same generation assay is used?

    <p>Due to differences in the detection of PTH fragments by assay-specific antibodies</p> Signup and view all the answers

    What is a candidate reference method for PTH assay?

    <p>Liquid chromatography with tandem mass spectrometry (LC-MS/MS)</p> Signup and view all the answers

    Where is the adrenal medulla located?

    <p>Inner region of the adrenal gland</p> Signup and view all the answers

    What is the basic structure found in cortical hormones?

    <p>Cyclopentanperhydrophenant (CP) ring</p> Signup and view all the answers

    What synthesizes cortical hormones from LDL?

    <p>Only G cells</p> Signup and view all the answers

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