Podcast
Questions and Answers
Which of the following is NOT a detrimental effect of sustained elevations or abnormally large increases in cytosolic free Ca2+?
Which of the following is NOT a detrimental effect of sustained elevations or abnormally large increases in cytosolic free Ca2+?
- Facilitation of ROS formation and damage in mitochondria
- Inhibition of membrane transporters (correct)
- Impairment of membrane function
- Activation of degradative Ca2+-dependent enzymes
What is believed to induce cellular injury through the release of lysosomal enzymes and toxicants into the cytoplasm?
What is believed to induce cellular injury through the release of lysosomal enzymes and toxicants into the cytoplasm?
- Sustained elevations in cytosolic free Ca2+
- Rupture of lysosomes (correct)
- Inhibition of energy production
- Increased ion permeability
Which of the following is NOT a key subcellular target of aminoglycosides, unleaded gasoline, and d-limonene?
Which of the following is NOT a key subcellular target of aminoglycosides, unleaded gasoline, and d-limonene?
- Mitochondria
- Endoplasmic reticulum
- Golgi apparatus
- Lysosomes (correct)
Which of the following enzyme families hydrolyzes phospholipids, potentially impairing membrane function?
Which of the following enzyme families hydrolyzes phospholipids, potentially impairing membrane function?
What is the primary cause of the loss of ATP, which results in the inhibition of membrane transporters that maintain internal ion balance?
What is the primary cause of the loss of ATP, which results in the inhibition of membrane transporters that maintain internal ion balance?
Which of the following enzymes is NOT mentioned in the passage as being activated by an increase in cytosolic free Ca2+?
Which of the following enzymes is NOT mentioned in the passage as being activated by an increase in cytosolic free Ca2+?
Which of the following statements about mitochondria is NOT true, according to the passage?
Which of the following statements about mitochondria is NOT true, according to the passage?
What is the primary mechanism by which toxicants disrupt cell volume and ion homeostasis, according to the passage?
What is the primary mechanism by which toxicants disrupt cell volume and ion homeostasis, according to the passage?
Which of the following statements about the distribution of Ca2+ in renal cells is true, according to the passage?
Which of the following statements about the distribution of Ca2+ in renal cells is true, according to the passage?
Which of the following statements is NOT true, based on the information provided in the passage?
Which of the following statements is NOT true, based on the information provided in the passage?
