Acute Inflammation Lecture 5 by Dr. Manar Ahmed Abdelrahman
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Questions and Answers

Which of the following is a characteristic of emigration during acute inflammation?

  • Leukocytes adhere to the endothelial surface
  • Leukocytes move out of the blood vessels
  • Leukocytes line the endothelial surface
  • Leukocytes roll along the endothelial surface (correct)
  • Which chemical substance is responsible for causing increased vascular permeability in acute inflammation?

  • Bradykinin
  • Histamine (correct)
  • Leukotrienes
  • C5a
  • What causes fever in acute inflammation?

  • Lysosomal enzymes
  • Exogenous cytokines
  • Endogenous pyrogens (correct)
  • Leukotrienes
  • What is the main action of chemical mediators in the inflammatory process?

    <p>Vascular dilatation</p> Signup and view all the answers

    In what type of acute inflammation is pus formation more likely to occur?

    <p>Suppurative (Purulent)</p> Signup and view all the answers

    What are the cardinal signs of acute inflammation?

    <p>Redness, swelling, heat, pain</p> Signup and view all the answers

    Which cells are the main inflammatory cells in acute inflammation?

    <p>Neutrophils</p> Signup and view all the answers

    What is the predominant cell type in chronic inflammation?

    <p>Lymphocytes</p> Signup and view all the answers

    Which type of inflammation is characterized by vascular proliferation and scarring?

    <p>Chronic inflammation</p> Signup and view all the answers

    What are the major components of acute inflammation?

    <p>Vascular changes, cellular events, chemical mediators</p> Signup and view all the answers

    Study Notes

    Characteristics of Acute Inflammation

    • Emigration of leukocytes from blood vessels to tissues is a characteristic of emigration during acute inflammation.

    Chemical Mediators of Acute Inflammation

    • Increased vascular permeability in acute inflammation is caused by histamine, a chemical substance.

    Causes of Fever in Acute Inflammation

    • Fever in acute inflammation is caused by pyrogens, such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha).

    Action of Chemical Mediators

    • Chemical mediators, such as histamine and bradykinin, increase blood flow, permeability, and pain in the inflammatory process.

    Type of Acute Inflammation with Pus Formation

    • Suppurative inflammation is the type of acute inflammation where pus formation is more likely to occur.

    Cardinal Signs of Acute Inflammation

    • The cardinal signs of acute inflammation are rubor (redness), dolor (pain), calor (heat), and tumor (swelling).

    Main Inflammatory Cells in Acute Inflammation

    • Neutrophils are the main inflammatory cells in acute inflammation.

    Predominant Cell Type in Chronic Inflammation

    • Macrophages are the predominant cell type in chronic inflammation.

    Characteristics of Chronic Inflammation

    • Chronic inflammation is characterized by vascular proliferation and scarring.

    Major Components of Acute Inflammation

    • The major components of acute inflammation are vasodilation, increased permeability, and leukocyte emigration.

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    Description

    Learn about the complex reaction of tissue and microcirculation to a pathogenic insult, characterized by the generation of inflammatory mediators and movement of fluid & leukocytes from the blood into extra vascular tissues. This lecture covers the definition and types of acute inflammation.

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