Acute Inflammation Lecture 5 by Dr. Manar Ahmed Abdelrahman

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10 Questions

Which of the following is a characteristic of emigration during acute inflammation?

Leukocytes roll along the endothelial surface

Which chemical substance is responsible for causing increased vascular permeability in acute inflammation?

Histamine

What causes fever in acute inflammation?

Endogenous pyrogens

What is the main action of chemical mediators in the inflammatory process?

Vascular dilatation

In what type of acute inflammation is pus formation more likely to occur?

Suppurative (Purulent)

What are the cardinal signs of acute inflammation?

Redness, swelling, heat, pain

Which cells are the main inflammatory cells in acute inflammation?

Neutrophils

What is the predominant cell type in chronic inflammation?

Lymphocytes

Which type of inflammation is characterized by vascular proliferation and scarring?

Chronic inflammation

What are the major components of acute inflammation?

Vascular changes, cellular events, chemical mediators

Study Notes

Characteristics of Acute Inflammation

  • Emigration of leukocytes from blood vessels to tissues is a characteristic of emigration during acute inflammation.

Chemical Mediators of Acute Inflammation

  • Increased vascular permeability in acute inflammation is caused by histamine, a chemical substance.

Causes of Fever in Acute Inflammation

  • Fever in acute inflammation is caused by pyrogens, such as interleukin-1 (IL-1) and tumor necrosis factor-alpha (TNF-alpha).

Action of Chemical Mediators

  • Chemical mediators, such as histamine and bradykinin, increase blood flow, permeability, and pain in the inflammatory process.

Type of Acute Inflammation with Pus Formation

  • Suppurative inflammation is the type of acute inflammation where pus formation is more likely to occur.

Cardinal Signs of Acute Inflammation

  • The cardinal signs of acute inflammation are rubor (redness), dolor (pain), calor (heat), and tumor (swelling).

Main Inflammatory Cells in Acute Inflammation

  • Neutrophils are the main inflammatory cells in acute inflammation.

Predominant Cell Type in Chronic Inflammation

  • Macrophages are the predominant cell type in chronic inflammation.

Characteristics of Chronic Inflammation

  • Chronic inflammation is characterized by vascular proliferation and scarring.

Major Components of Acute Inflammation

  • The major components of acute inflammation are vasodilation, increased permeability, and leukocyte emigration.

Learn about the complex reaction of tissue and microcirculation to a pathogenic insult, characterized by the generation of inflammatory mediators and movement of fluid & leukocytes from the blood into extra vascular tissues. This lecture covers the definition and types of acute inflammation.

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