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Questions and Answers
What role do central or arterial chemoreceptors play in the respiratory system's regulation of acid–base balance?
What role do central or arterial chemoreceptors play in the respiratory system's regulation of acid–base balance?
Which condition can lead to respiratory acidosis?
Which condition can lead to respiratory acidosis?
Which of the following statements about metabolic compensation in respiratory acidosis is true?
Which of the following statements about metabolic compensation in respiratory acidosis is true?
Why are older adults more susceptible to acidosis?
Why are older adults more susceptible to acidosis?
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What characterizes respiratory alkalosis?
What characterizes respiratory alkalosis?
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How do kidneys contribute to acid–base balance?
How do kidneys contribute to acid–base balance?
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What is the main factor that leads to decreased oxygen delivery to cells in respiratory acidosis?
What is the main factor that leads to decreased oxygen delivery to cells in respiratory acidosis?
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What is a common cause of acid–base imbalances in patients on medications?
What is a common cause of acid–base imbalances in patients on medications?
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What is the primary role of the kidneys in maintaining acid-base balance?
What is the primary role of the kidneys in maintaining acid-base balance?
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What occurs in metabolic acidosis regarding potassium levels?
What occurs in metabolic acidosis regarding potassium levels?
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Which physiological change occurs in response to metabolic alkalosis?
Which physiological change occurs in response to metabolic alkalosis?
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What is the effect of pulmonary compensation in metabolic acidosis?
What is the effect of pulmonary compensation in metabolic acidosis?
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What is typically the time frame for renal compensation to establish a steady state in response to a pH imbalance?
What is typically the time frame for renal compensation to establish a steady state in response to a pH imbalance?
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Which of the following describes the potential sequelae of metabolic alkalosis?
Which of the following describes the potential sequelae of metabolic alkalosis?
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Which of the following is NOT a compensatory mechanism for metabolic alkalosis?
Which of the following is NOT a compensatory mechanism for metabolic alkalosis?
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In metabolic acidosis, what is the relationship between H+ and Na+ retention in the kidneys?
In metabolic acidosis, what is the relationship between H+ and Na+ retention in the kidneys?
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What is the primary goal of providing emotional and psychological support to patients and their families?
What is the primary goal of providing emotional and psychological support to patients and their families?
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How does holistic care differ from traditional care approaches?
How does holistic care differ from traditional care approaches?
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What is a key component of facilitating communication in healthcare settings?
What is a key component of facilitating communication in healthcare settings?
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Why is advance care planning important for patients and families?
Why is advance care planning important for patients and families?
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What does enhancing the quality of life for patients involve?
What does enhancing the quality of life for patients involve?
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What is the normal range for pH in the human body?
What is the normal range for pH in the human body?
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If a patient's pH is 7.49, what is the interpretation of that pH value?
If a patient's pH is 7.49, what is the interpretation of that pH value?
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What is the role of the phosphate buffer system in the body?
What is the role of the phosphate buffer system in the body?
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How does the carbonic acid bicarbonate buffer system respond to a decrease in pH?
How does the carbonic acid bicarbonate buffer system respond to a decrease in pH?
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When interpreting respiratory status, a PaCO₂ of 62 indicates what condition?
When interpreting respiratory status, a PaCO₂ of 62 indicates what condition?
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What physiological process occurs when pH levels increase?
What physiological process occurs when pH levels increase?
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What is the appropriate term for a situation where the un-matching value is outside of the normal range but reflects the opposite of the pH value?
What is the appropriate term for a situation where the un-matching value is outside of the normal range but reflects the opposite of the pH value?
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Which mechanism is considered the last resort for maintaining acid-base balance in the body?
Which mechanism is considered the last resort for maintaining acid-base balance in the body?
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In the case where a patient presents with a pH of 7.49, a PaCO₂ of 62, and an HCO₃ of 46, how would you classify the primary disturbance?
In the case where a patient presents with a pH of 7.49, a PaCO₂ of 62, and an HCO₃ of 46, how would you classify the primary disturbance?
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What is an essential goal of palliative care for patients experiencing distressing symptoms?
What is an essential goal of palliative care for patients experiencing distressing symptoms?
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What happens to bicarbonate in the kidneys during alkalosis?
What happens to bicarbonate in the kidneys during alkalosis?
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In the context of stress management for family members in palliative care, which of the following approaches would be most effective?
In the context of stress management for family members in palliative care, which of the following approaches would be most effective?
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What is the immediate action of the body when faced with an acid-base imbalance?
What is the immediate action of the body when faced with an acid-base imbalance?
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Which laboratory value is primarily involved in metabolic compensation?
Which laboratory value is primarily involved in metabolic compensation?
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During acidosis, how do the lungs help restore balance?
During acidosis, how do the lungs help restore balance?
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What is the primary function of proteins in the buffering system?
What is the primary function of proteins in the buffering system?
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In what way does the phosphate buffer system function to manage H+ concentration?
In what way does the phosphate buffer system function to manage H+ concentration?
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How do kidneys contribute to acid-base balance through sodium and chloride ions?
How do kidneys contribute to acid-base balance through sodium and chloride ions?
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What is a primary cause of metabolic acidosis?
What is a primary cause of metabolic acidosis?
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Which of the following is a source of bases?
Which of the following is a source of bases?
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Which condition is most likely to result in respiratory acidosis?
Which condition is most likely to result in respiratory acidosis?
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What effect does excessive exhalation of CO2 have on blood pH?
What effect does excessive exhalation of CO2 have on blood pH?
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What is a common sign of respiratory alkalosis?
What is a common sign of respiratory alkalosis?
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Which of the following is NOT a characteristic of metabolic alkalosis?
Which of the following is NOT a characteristic of metabolic alkalosis?
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What could cause excessive production of metabolic acids?
What could cause excessive production of metabolic acids?
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Which physiological response indicates compensatory mechanisms during acidosis?
Which physiological response indicates compensatory mechanisms during acidosis?
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Which symptom is commonly associated with metabolic acidosis?
Which symptom is commonly associated with metabolic acidosis?
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What is a potential cause of metabolic alkalosis through the gastrointestinal tract?
What is a potential cause of metabolic alkalosis through the gastrointestinal tract?
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Hyperkalemia is commonly associated with which type of acid-base imbalance?
Hyperkalemia is commonly associated with which type of acid-base imbalance?
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Which of the following statements is correct regarding the effect of diuretics on acid-base balance?
Which of the following statements is correct regarding the effect of diuretics on acid-base balance?
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What physiological change occurs during respiratory acidosis?
What physiological change occurs during respiratory acidosis?
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What characterizes metabolic alkalosis in terms of blood gas levels?
What characterizes metabolic alkalosis in terms of blood gas levels?
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Study Notes
Acid-Base Balance
- The respiratory and renal systems maintain homeostasis, regulating the body's acid-base balance.
- Buffering mechanisms maintain balance.
- Common causes of imbalances include conditions like diabetes, chronic kidney disease, and COPD.
- Normal blood gas levels are crucial.
- Holistic nursing care is applied to clients needing chronic care management.
- pH (acidity/alkalinity): 7.35-7.45
- PaCO2 (carbon dioxide, acidic): 35-45
- HCO3 (bicarbonate, base): 22-26
Older Adults and Acidosis
- Older adults are more susceptible to acidosis due to factors like diuretic use, ASA, antacids, and decreased renal and respiratory function.
- Chronic health conditions (diabetes, COPD, etc.) also increase susceptibility.
Respiratory System Regulation
- Lungs control PCO2 levels to maintain acid-base balance by altering ventilation rate.
- This process is fast, occurring within minutes or hours.
- Respiratory acidosis occurs with ventilation impairment (high PCO2, low pH). In acidosis, hemoglobin releases less oxygen to tissues.
- Respiratory alkalosis results from hyperventilation (low PCO2, high pH). In alkalosis, hemoglobin holds onto oxygen more tightly.
Renal System Regulation
- Kidneys adjust HCO3- (bicarbonate) retention and H+ excretion to regulate acid-base balance.
- Compensation is slower, taking days.
- Metabolic acidosis (low pH, low HCO3-) occurs with excessive acid production or loss of bicarbonate.
- Metabolic alkalosis (high pH, high HCO3-) is from excessive loss of acids or excessive base intake.
Buffer Systems
- Chemical buffers (proteins, phosphate) and physiological buffers (lungs, kidneys) maintain a stable pH.
- Phosphate buffer system involves HPO42- and H2PO4–, regulating blood pH.
- Bicarbonate buffer functions in interstitial fluid and blood. This system is most important in adjusting to changes in CO2.
Acid-Base Imbalances
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ACIDOSIS:
- Inside cell: buffers are proteins and phosphate
- Outside cell: buffers are proteins and bicarbonate
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ALKALOSIS
- Inside cell: buffers are proteins and phosphate
- Outside cell: buffers are proteins and bicarbonate
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Respiratory and metabolic acidosis and alkalosis have distinct causes, symptoms, and compensation mechanisms.
Blood Gas Analysis
- pH, PaCO2, and HCO3 values are used to assess acid-base balance.
- Analyzing blood gas levels helps determine whether the imbalance is respiratory or metabolic, or if the body is compensating.
- Normal ranges are crucial in interpretation.
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Description
This quiz focuses on the acid-base balance in the body, emphasizing the roles of the respiratory and renal systems. It also discusses the susceptibility of older adults to acidosis and the implications of chronic health conditions. Test your knowledge on blood gas levels and buffering mechanisms.