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Questions and Answers
What is the primary reason Leucovorin is administered with 5 FU?
What is the primary reason Leucovorin is administered with 5 FU?
Where is 5 FU metabolized rapidly?
Where is 5 FU metabolized rapidly?
What can elevated levels of dihydropyrimidine dehydrogenase (DPD) lead to?
What can elevated levels of dihydropyrimidine dehydrogenase (DPD) lead to?
Which enzyme is responsible for the hydrolysis of capecitabine to 5FU?
Which enzyme is responsible for the hydrolysis of capecitabine to 5FU?
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In which phase of the cell cycle does 5 FU produce its anticancer effect?
In which phase of the cell cycle does 5 FU produce its anticancer effect?
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What can happen to patients with DPD deficiency when treated with 5-FU?
What can happen to patients with DPD deficiency when treated with 5-FU?
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What is the main cytotoxic activity of capecitabine and 5-FU?
What is the main cytotoxic activity of capecitabine and 5-FU?
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Which enzyme is primarily concentrated in tumors and catalyzes the conversion of thymidine?
Which enzyme is primarily concentrated in tumors and catalyzes the conversion of thymidine?
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What is the major clinical use of cytarabine?
What is the major clinical use of cytarabine?
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Which metabolite of cytarabine is pharmacologically inactive?
Which metabolite of cytarabine is pharmacologically inactive?
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How does azacitidine primarily inhibit RNA processing and function?
How does azacitidine primarily inhibit RNA processing and function?
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Which phase of the cell cycle is affected by Ara-CTP, the active form of cytarabine?
Which phase of the cell cycle is affected by Ara-CTP, the active form of cytarabine?
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