3 Lines of Defense in the Immune System

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What is the main function of dendritic cells in the body?

Patrol the body for antigens that cause infections

Why are the layers of the skin considered a barrier to microbes and pathogens?

They constantly shed skin cells, eliminating attached microbes

Which substance in sweat plays a role in destroying bacterial cell walls?

Lysozyme

How do normal microbiota contribute to microbial antagonism?

Consume nutrients needed by pathogens and change pH to favor their own growth

What is the specific role of iron-binding proteins in plasma during non-specific defense?

Help in sequestering iron to prevent its use by pathogens

Which factor makes mucous membranes a common portal of entry for pathogens?

Thin, tightly packed cells that are not shed as easily

What is the function of Toll-like receptors (TLRs) in the immune system?

Recognize PAMPS on microbes and initiate immune responses

Which white blood cell type can deploy Neutrophil extracellular traps (NETs)?

Neutrophils

What is a common sign of disease that involves an abnormally large number of eosinophils in the blood?

Eosinophilia

What is the primary function of interferons Type I in the immune response?

Produce antiviral proteins

Which cells are responsible for nonphagocytic killing of pathogens by secreting antimicrobial chemicals?

Eosinophils, NK cells, neutrophils

Which white blood cell type transforms into macrophages and can be fixed or wandering in the body?

Monocytes

Learn about the three lines of defense in the immune system: Innate External Barriers, Nonspecific Innate Internal Defense, and Adaptive Specific Defense. Explore how the skin functions as the first line of defense against pathogens and microbes.

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