Pulm Meds 1
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Questions and Answers

What is the main mechanism of action of sympathomimetic agents like beta-2 selective agents?

  • Inhibition of adenyl cyclase
  • Stimulation of muscarinic receptors
  • Stimulation of β adrenergic receptors in airway smooth muscle (correct)
  • Promotion of cAMP breakdown

    • What is a common adverse effect of beta 2 agonists according to the text?

  • Osteoporosis
  • Hypertension
  • Hyperglycemia
  • Hypokalemia (correct)

    • According to GINA guidelines, why do they recommend against SABA monotherapy?

  • Due to higher rate of exacerbations compared to ICS-containing therapy (correct)
  • Due to potential metabolic alkalosis
  • Due to decreased bronchodilation efficiency
  • Due to concerns about cardiomyopathy development

    • In what form are short-acting beta agonists (SABA) available for use?

    <p>Metered Dose Inhalers (MDI), Dry Powder Inhalers (DPI), Nebulizer solutions</p> Signup and view all the answers

    What is considered a sign of good asthma control according to the text?

    <p>Limited/eliminated need for SABA use regularly</p> Signup and view all the answers

    What is the recommended use of SABA according to NHLBI 2020 guidelines for intermittent asthma?

    <p>As needed as monotherapy for intermittent asthma</p> Signup and view all the answers

    What is the indication for the use of Albuterol according to the text?

    <p>Treatment of chronic obstructive pulmonary disease (COPD)</p> Signup and view all the answers

    What is the onset of action for Albuterol using a metered dose inhaler (MDI) as stated in the text?

    <p>$5-8$ minutes</p> Signup and view all the answers

    What is the primary mechanism of action of Albuterol as mentioned in the text?

    <p>Binds to β2 adrenergic receptors leading to bronchodilation</p> Signup and view all the answers

    What is considered a common problem with asthma medications according to the text?

    <p>Poor medication adherence</p> Signup and view all the answers

    What condition does NHLBI 2020 guidelines recommend SABA monotherapy for, as mentioned in the text?

    <p>Intermittent asthma</p> Signup and view all the answers

    Sympathomimetic agents cause bronchodilation by inhibiting adenyl cyclase.

    <p>False</p> Signup and view all the answers

    NHLBI 2020 guidelines recommend SABA monotherapy for persistent asthma.

    <p>False</p> Signup and view all the answers

    Albuterol has anti-inflammatory effects and can be used as monotherapy for persistent asthma.

    <p>False</p> Signup and view all the answers

    Tolerance to beta agonists can lead to heightened bronchodilatory effects.

    <p>False</p> Signup and view all the answers

    SABA inhalers are recommended for use as needed in the treatment of persistent asthma according to GINA guidelines.

    <p>False</p> Signup and view all the answers

    What is the primary reason for GINA guidelines recommending against SABA monotherapy?

    <p>Higher rate of exacerbations than inhaled corticosteroid (ICS) containing therapy</p> Signup and view all the answers

    Which condition do NHLBI 2020 guidelines recommend SABA monotherapy for?

    <p>Intermittent asthma</p> Signup and view all the answers

    What is a common problem with asthma medications according to the text?

    <p>Poor inhaler technique</p> Signup and view all the answers

    What is the primary mechanism of action of sympathomimetic agents like beta-2 selective agents?

    <p>Promoting bronchodilation by binding to β adrenergic receptors</p> Signup and view all the answers

    What is considered a sign of good asthma control according to the text?

    <p>Limited/eliminated need for SABA use regularly</p> Signup and view all the answers

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