Pulm Meds 1

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Questions and Answers

What is the main mechanism of action of sympathomimetic agents like beta-2 selective agents?

  • Inhibition of adenyl cyclase
  • Stimulation of muscarinic receptors
  • Stimulation of β adrenergic receptors in airway smooth muscle (correct)
  • Promotion of cAMP breakdown

What is a common adverse effect of beta 2 agonists according to the text?

  • Osteoporosis
  • Hypertension
  • Hyperglycemia
  • Hypokalemia (correct)

According to GINA guidelines, why do they recommend against SABA monotherapy?

  • Due to higher rate of exacerbations compared to ICS-containing therapy (correct)
  • Due to potential metabolic alkalosis
  • Due to decreased bronchodilation efficiency
  • Due to concerns about cardiomyopathy development

In what form are short-acting beta agonists (SABA) available for use?

<p>Metered Dose Inhalers (MDI), Dry Powder Inhalers (DPI), Nebulizer solutions (B)</p> Signup and view all the answers

What is considered a sign of good asthma control according to the text?

<p>Limited/eliminated need for SABA use regularly (A)</p> Signup and view all the answers

What is the recommended use of SABA according to NHLBI 2020 guidelines for intermittent asthma?

<p>As needed as monotherapy for intermittent asthma (B)</p> Signup and view all the answers

What is the indication for the use of Albuterol according to the text?

<p>Treatment of chronic obstructive pulmonary disease (COPD) (D)</p> Signup and view all the answers

What is the onset of action for Albuterol using a metered dose inhaler (MDI) as stated in the text?

<p>$5-8$ minutes (A)</p> Signup and view all the answers

What is the primary mechanism of action of Albuterol as mentioned in the text?

<p>Binds to β2 adrenergic receptors leading to bronchodilation (A)</p> Signup and view all the answers

What is considered a common problem with asthma medications according to the text?

<p>Poor medication adherence (C)</p> Signup and view all the answers

What condition does NHLBI 2020 guidelines recommend SABA monotherapy for, as mentioned in the text?

<p>Intermittent asthma (D)</p> Signup and view all the answers

Sympathomimetic agents cause bronchodilation by inhibiting adenyl cyclase.

<p>False (B)</p> Signup and view all the answers

NHLBI 2020 guidelines recommend SABA monotherapy for persistent asthma.

<p>False (B)</p> Signup and view all the answers

Albuterol has anti-inflammatory effects and can be used as monotherapy for persistent asthma.

<p>False (B)</p> Signup and view all the answers

Tolerance to beta agonists can lead to heightened bronchodilatory effects.

<p>False (B)</p> Signup and view all the answers

SABA inhalers are recommended for use as needed in the treatment of persistent asthma according to GINA guidelines.

<p>False (B)</p> Signup and view all the answers

What is the primary reason for GINA guidelines recommending against SABA monotherapy?

<p>Higher rate of exacerbations than inhaled corticosteroid (ICS) containing therapy (C)</p> Signup and view all the answers

Which condition do NHLBI 2020 guidelines recommend SABA monotherapy for?

<p>Intermittent asthma (C)</p> Signup and view all the answers

What is a common problem with asthma medications according to the text?

<p>Poor inhaler technique (A)</p> Signup and view all the answers

What is the primary mechanism of action of sympathomimetic agents like beta-2 selective agents?

<p>Promoting bronchodilation by binding to β adrenergic receptors (A)</p> Signup and view all the answers

What is considered a sign of good asthma control according to the text?

<p>Limited/eliminated need for SABA use regularly (B)</p> Signup and view all the answers

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