21 Questions
What is the main mechanism of action of sympathomimetic agents like beta-2 selective agents?
Stimulation of β adrenergic receptors in airway smooth muscle
What is a common adverse effect of beta 2 agonists according to the text?
Hypokalemia
According to GINA guidelines, why do they recommend against SABA monotherapy?
Due to higher rate of exacerbations compared to ICS-containing therapy
In what form are short-acting beta agonists (SABA) available for use?
Metered Dose Inhalers (MDI), Dry Powder Inhalers (DPI), Nebulizer solutions
What is considered a sign of good asthma control according to the text?
Limited/eliminated need for SABA use regularly
What is the recommended use of SABA according to NHLBI 2020 guidelines for intermittent asthma?
As needed as monotherapy for intermittent asthma
What is the indication for the use of Albuterol according to the text?
Treatment of chronic obstructive pulmonary disease (COPD)
What is the onset of action for Albuterol using a metered dose inhaler (MDI) as stated in the text?
$5-8$ minutes
What is the primary mechanism of action of Albuterol as mentioned in the text?
Binds to β2 adrenergic receptors leading to bronchodilation
What is considered a common problem with asthma medications according to the text?
Poor medication adherence
What condition does NHLBI 2020 guidelines recommend SABA monotherapy for, as mentioned in the text?
Intermittent asthma
Sympathomimetic agents cause bronchodilation by inhibiting adenyl cyclase.
False
NHLBI 2020 guidelines recommend SABA monotherapy for persistent asthma.
False
Albuterol has anti-inflammatory effects and can be used as monotherapy for persistent asthma.
False
Tolerance to beta agonists can lead to heightened bronchodilatory effects.
False
SABA inhalers are recommended for use as needed in the treatment of persistent asthma according to GINA guidelines.
False
What is the primary reason for GINA guidelines recommending against SABA monotherapy?
Higher rate of exacerbations than inhaled corticosteroid (ICS) containing therapy
Which condition do NHLBI 2020 guidelines recommend SABA monotherapy for?
Intermittent asthma
What is a common problem with asthma medications according to the text?
Poor inhaler technique
What is the primary mechanism of action of sympathomimetic agents like beta-2 selective agents?
Promoting bronchodilation by binding to β adrenergic receptors
What is considered a sign of good asthma control according to the text?
Limited/eliminated need for SABA use regularly
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