Podcast
Questions and Answers
What is the main mechanism of action of sympathomimetic agents like beta-2 selective agents?
What is the main mechanism of action of sympathomimetic agents like beta-2 selective agents?
- Inhibition of adenyl cyclase
- Stimulation of muscarinic receptors
- Stimulation of β adrenergic receptors in airway smooth muscle (correct)
- Promotion of cAMP breakdown
What is a common adverse effect of beta 2 agonists according to the text?
What is a common adverse effect of beta 2 agonists according to the text?
- Osteoporosis
- Hypertension
- Hyperglycemia
- Hypokalemia (correct)
According to GINA guidelines, why do they recommend against SABA monotherapy?
According to GINA guidelines, why do they recommend against SABA monotherapy?
- Due to higher rate of exacerbations compared to ICS-containing therapy (correct)
- Due to potential metabolic alkalosis
- Due to decreased bronchodilation efficiency
- Due to concerns about cardiomyopathy development
In what form are short-acting beta agonists (SABA) available for use?
In what form are short-acting beta agonists (SABA) available for use?
What is considered a sign of good asthma control according to the text?
What is considered a sign of good asthma control according to the text?
What is the recommended use of SABA according to NHLBI 2020 guidelines for intermittent asthma?
What is the recommended use of SABA according to NHLBI 2020 guidelines for intermittent asthma?
What is the indication for the use of Albuterol according to the text?
What is the indication for the use of Albuterol according to the text?
What is the onset of action for Albuterol using a metered dose inhaler (MDI) as stated in the text?
What is the onset of action for Albuterol using a metered dose inhaler (MDI) as stated in the text?
What is the primary mechanism of action of Albuterol as mentioned in the text?
What is the primary mechanism of action of Albuterol as mentioned in the text?
What is considered a common problem with asthma medications according to the text?
What is considered a common problem with asthma medications according to the text?
What condition does NHLBI 2020 guidelines recommend SABA monotherapy for, as mentioned in the text?
What condition does NHLBI 2020 guidelines recommend SABA monotherapy for, as mentioned in the text?
Sympathomimetic agents cause bronchodilation by inhibiting adenyl cyclase.
Sympathomimetic agents cause bronchodilation by inhibiting adenyl cyclase.
NHLBI 2020 guidelines recommend SABA monotherapy for persistent asthma.
NHLBI 2020 guidelines recommend SABA monotherapy for persistent asthma.
Albuterol has anti-inflammatory effects and can be used as monotherapy for persistent asthma.
Albuterol has anti-inflammatory effects and can be used as monotherapy for persistent asthma.
Tolerance to beta agonists can lead to heightened bronchodilatory effects.
Tolerance to beta agonists can lead to heightened bronchodilatory effects.
SABA inhalers are recommended for use as needed in the treatment of persistent asthma according to GINA guidelines.
SABA inhalers are recommended for use as needed in the treatment of persistent asthma according to GINA guidelines.
What is the primary reason for GINA guidelines recommending against SABA monotherapy?
What is the primary reason for GINA guidelines recommending against SABA monotherapy?
Which condition do NHLBI 2020 guidelines recommend SABA monotherapy for?
Which condition do NHLBI 2020 guidelines recommend SABA monotherapy for?
What is a common problem with asthma medications according to the text?
What is a common problem with asthma medications according to the text?
What is the primary mechanism of action of sympathomimetic agents like beta-2 selective agents?
What is the primary mechanism of action of sympathomimetic agents like beta-2 selective agents?
What is considered a sign of good asthma control according to the text?
What is considered a sign of good asthma control according to the text?
