Pulm Meds 5
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Questions and Answers

What is the primary purpose of Ethambutol in tuberculosis treatment?

  • Help eliminate remaining TB bacilli
  • Sterilize the TB bacilli
  • Prevent the emergence of Rifampin resistance (correct)
  • Reduce treatment failure and relapse

Why does the Continuation Phase of tuberculosis treatment last 4 or 7 months?

  • To eliminate remaining TB bacilli (correct)
  • To treat patients with HIV who are not receiving antiviral therapy
  • To reduce treatment failure and relapse
  • To include Pyrazinamide in the intensive phase

What is the standard of care for initiating treatment of tuberculosis?

  • Nine-drug regimen
  • Four-drug regimen (correct)
  • Two-drug regimen
  • Six-drug regimen

Which drug is primarily responsible for inhibiting the biosynthesis of mycolic acid in tuberculosis treatment?

<p>Isoniazid (A)</p> Signup and view all the answers

What is the main route of elimination for Rifampin in the body?

<p>Feces (A)</p> Signup and view all the answers

What is the purpose of the intensive phase of tuberculosis (TB) treatment?

<p>To prevent the emergence of drug resistance (D)</p> Signup and view all the answers

Why is monotherapy usually not recommended for anti-mycobacteria drug treatment?

<p>Due to the risk of drug resistance (B)</p> Signup and view all the answers

Which drugs should be included during the intensive phase of TB treatment?

<p>Isoniazid, Rifampin, Pyrazinamide, and Ethambutol (D)</p> Signup and view all the answers

Why are anti-mycobacteria drugs considered diverse compounds?

<p>Due to their varied chemical structures (C)</p> Signup and view all the answers

What is the activity of Isoniazid and Rifampin during the intensive phase of TB treatment?

<p>They kill active growing TB bacilli (C)</p> Signup and view all the answers

Pyrazinamide is included in the intensive phase of tuberculosis treatment.

<p>True (A)</p> Signup and view all the answers

Rifampin has potent sterilizing activity against tuberculosis bacilli.

<p>True (A)</p> Signup and view all the answers

Isoniazid is primarily eliminated through renal excretion.

<p>True (A)</p> Signup and view all the answers

Ethambutol is used as monotherapy for latent tuberculosis.

<p>False (B)</p> Signup and view all the answers

Directly observed therapy (DOT) can be conducted electronically to improve adherence to tuberculosis treatment.

<p>True (A)</p> Signup and view all the answers

Why is nonadherence considered a major problem in controlling tuberculosis?

<p>It can lead to drug resistance (C)</p> Signup and view all the answers

Which drug is primarily responsible for inhibiting the biosynthesis of mycolic acid in tuberculosis treatment?

<p>Isoniazid (D)</p> Signup and view all the answers

What is the main route of elimination for Rifampin in the body?

<p>Biliary excretion (D)</p> Signup and view all the answers

Why is Pyrazinamide not included in the Continuation Phase of tuberculosis treatment for some patients?

<p>It has potent sterilizing activity against tuberculosis bacilli (D)</p> Signup and view all the answers

What is the primary purpose of Ethambutol in tuberculosis treatment?

<p>To prevent emergence of Rifampin resistance (D)</p> Signup and view all the answers

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