Pulm Meds 2

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Which drug is indicated for the treatment of symptoms associated with chronic asthma or other chronic lung diseases?

Theophylline

What is the mechanism of action of the drug Ipratropium?

Muscarinic cholinergic receptor antagonist

What is the most significant adverse effect associated with Ipratropium?

Paradoxical bronchospasm

Which anticholinergic agent has a duration of 2-4 hours when administered through metered-dose inhaler (MDI)?

Tiotropium

What is the primary mechanism of action of Tiotropium?

Muscarinic cholinergic receptor antagonist

What is an important warning/caution associated with Tiotropium use?

Not indicated as a rescue inhaler for acute bronchospasm

Which medication is indicated for moderate to severe asthma in patients older than 6 years old?

Tiotropium

What is the primary mechanism of action of Theophylline?

Inhibition of phosphodiesterase enzymes

What is an important warning/caution associated with Ipratropium use?

Paradoxical bronchospasm

What can be used as monotherapy or as a combination with other bronchodilators, especially beta adrenergic?

Ipratropium/albuterol

Methylxanthine drugs are no longer recommended for the treatment of COPD according to the new GOLD criteria.

True

Theophylline has a relatively narrow therapeutic range with a low incidence of adverse effects.

False

Ipratropium is well absorbed systemically after inhalation.

False

Tiotropium is indicated for the treatment of asthma in patients younger than 6 years old.

False

Ipratropium/albuterol combination inhaler is indicated as a rescue inhaler for acute bronchospasm.

False

What factor contributes to the removal of methylxanthine drugs from the 2018 GOLD criteria for COPD treatment?

Risk of side effects outweighs benefits

Which drug has a relatively weak bronchodilator effect and a narrow therapeutic range?

Theophylline

What is the primary mechanism of action of Ipratropium?

Antagonism of muscarinic cholinergic receptors

Which drug has a duration of 2-4 hours when administered through a metered-dose inhaler (MDI)?

Ipratropium

Which anticholinergic agent is indicated for moderate to severe asthma in patients older than 6 years old?

Tiotropium

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