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Pulm Meds 4
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Pulm Meds 4

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Questions and Answers

What substance do monoclonal antibodies target to treat asthma?

  • Leukotrienes
  • Immunoglobulin E (IgE) (correct)
  • Histamine
  • Prostaglandins

    • Which cytokines associated with asthma are targeted by monoclonal antibodies?

  • Interleukin-10 (IL-10) and Interleukin-12 (IL-12)
  • Interleukin-4 (IL-4) and Interleukin-5 (IL-5) (correct)
  • Interleukin-6 (IL-6) and Interleukin-8 (IL-8)
  • Interleukin-1 (IL-1) and Interleukin-6 (IL-6)

    • What are eosinophils involved in?

  • Producing histamine in the lungs
  • Suppressing the immune response
  • Breaking down allergens
  • Producing mucus and fluid that trigger bronchospasms (correct)

    • What is the primary purpose of monoclonal antibodies in treating asthma?

    <p>To reduce exacerbation rates and improve asthma control</p> Signup and view all the answers

    What is the most common adverse effect associated with monoclonal antibodies for asthma treatment?

    <p>Injection site pain</p> Signup and view all the answers

    Why should the initiation of omalizumab be done in a healthcare setting?

    <p>To monitor the patient for allergic reactions</p> Signup and view all the answers

    What age group can receive dupilumab for the treatment of asthma?

    <p>Adults and children 12 and older</p> Signup and view all the answers

    In which cases are monoclonal antibodies used for the treatment of asthma?

    <p>Severe cases refractory to high dose ICS therapy</p> Signup and view all the answers

    What should be avoided when prescribing monoclonal antibodies for asthma treatment?

    <p>'Patients with severe infection, especially parasitic infection'</p> Signup and view all the answers

    What is the major side effect of omalizumab?

    <p>Anaphylaxis</p> Signup and view all the answers

    Monoclonal antibodies for the treatment of asthma target only interleukins associated with asthma.

    <p>False</p> Signup and view all the answers

    Omalizumab (Xolair) is administered orally for the treatment of asthma.

    <p>False</p> Signup and view all the answers

    Tezepelumab (Tezspire) is not approved for use in children under 12 years old for the treatment of asthma.

    <p>True</p> Signup and view all the answers

    Monoclonal antibodies for the treatment of asthma are primarily used as a replacement for inhaled and oral corticosteroids.

    <p>False</p> Signup and view all the answers

    Benralizumab (Fasenra) targets interleukin-4 for the treatment of asthma.

    <p>False</p> Signup and view all the answers

    Which substance do monoclonal antibodies target to treat asthma?

    <p>Immunoglobulin E (IgE)</p> Signup and view all the answers

    What is the main role of eosinophils in the context of asthma?

    <p>Producing mucus and fluid triggering bronchospasms</p> Signup and view all the answers

    What is the primary caution associated with the use of monoclonal antibodies for asthma treatment?

    <p>Allergic reaction including anaphylaxis</p> Signup and view all the answers

    Which allergic inflammatory biomarkers are used to identify patients suitable for monoclonal antibodies treatment for asthma?

    <p>Serum IgE and blood eosinophil count</p> Signup and view all the answers

    What is the key purpose of monoclonal antibodies in treating severe asthma?

    <p>Improving asthma control and quality of life</p> Signup and view all the answers

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