Pulm Meds 4
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Questions and Answers

What substance do monoclonal antibodies target to treat asthma?

  • Leukotrienes
  • Immunoglobulin E (IgE) (correct)
  • Histamine
  • Prostaglandins

Which cytokines associated with asthma are targeted by monoclonal antibodies?

  • Interleukin-10 (IL-10) and Interleukin-12 (IL-12)
  • Interleukin-4 (IL-4) and Interleukin-5 (IL-5) (correct)
  • Interleukin-6 (IL-6) and Interleukin-8 (IL-8)
  • Interleukin-1 (IL-1) and Interleukin-6 (IL-6)

What are eosinophils involved in?

  • Producing histamine in the lungs
  • Suppressing the immune response
  • Breaking down allergens
  • Producing mucus and fluid that trigger bronchospasms (correct)

What is the primary purpose of monoclonal antibodies in treating asthma?

<p>To reduce exacerbation rates and improve asthma control (D)</p> Signup and view all the answers

What is the most common adverse effect associated with monoclonal antibodies for asthma treatment?

<p>Injection site pain (C)</p> Signup and view all the answers

Why should the initiation of omalizumab be done in a healthcare setting?

<p>To monitor the patient for allergic reactions (A)</p> Signup and view all the answers

What age group can receive dupilumab for the treatment of asthma?

<p>Adults and children 12 and older (C)</p> Signup and view all the answers

In which cases are monoclonal antibodies used for the treatment of asthma?

<p>Severe cases refractory to high dose ICS therapy (A)</p> Signup and view all the answers

What should be avoided when prescribing monoclonal antibodies for asthma treatment?

<p>'Patients with severe infection, especially parasitic infection' (C)</p> Signup and view all the answers

What is the major side effect of omalizumab?

<p>Anaphylaxis (B)</p> Signup and view all the answers

Monoclonal antibodies for the treatment of asthma target only interleukins associated with asthma.

<p>False (B)</p> Signup and view all the answers

Omalizumab (Xolair) is administered orally for the treatment of asthma.

<p>False (B)</p> Signup and view all the answers

Tezepelumab (Tezspire) is not approved for use in children under 12 years old for the treatment of asthma.

<p>True (A)</p> Signup and view all the answers

Monoclonal antibodies for the treatment of asthma are primarily used as a replacement for inhaled and oral corticosteroids.

<p>False (B)</p> Signup and view all the answers

Benralizumab (Fasenra) targets interleukin-4 for the treatment of asthma.

<p>False (B)</p> Signup and view all the answers

Which substance do monoclonal antibodies target to treat asthma?

<p>Immunoglobulin E (IgE) (D)</p> Signup and view all the answers

What is the main role of eosinophils in the context of asthma?

<p>Producing mucus and fluid triggering bronchospasms (B)</p> Signup and view all the answers

What is the primary caution associated with the use of monoclonal antibodies for asthma treatment?

<p>Allergic reaction including anaphylaxis (D)</p> Signup and view all the answers

Which allergic inflammatory biomarkers are used to identify patients suitable for monoclonal antibodies treatment for asthma?

<p>Serum IgE and blood eosinophil count (B)</p> Signup and view all the answers

What is the key purpose of monoclonal antibodies in treating severe asthma?

<p>Improving asthma control and quality of life (D)</p> Signup and view all the answers

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