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MODULE 5 PAP Questions PDF

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Summary

This document contains pharmaceutical science questions, including topics such as creams, filters, hardness, viscosity, and more. It covers various aspects of pharmaceutical preparation and testing, like sterilization methods and materials.

Full Transcript

MODULE 5 1. Less viscous & lighter than ointments, non-greasy character - CREAMS 2. Sterile production area - 99.97% efficiency (≤0.3um) 3. Minimum requirement for efficiency of HEPA Filters - 99.99% effective against 0.3 microns 4. Encapsulating area - 24 °C, 30% RH 5. Roche Friabilator - FRIABILIT...

MODULE 5 1. Less viscous & lighter than ointments, non-greasy character - CREAMS 2. Sterile production area - 99.97% efficiency (≤0.3um) 3. Minimum requirement for efficiency of HEPA Filters - 99.99% effective against 0.3 microns 4. Encapsulating area - 24 °C, 30% RH 5. Roche Friabilator - FRIABILITY 6. Stokes Monsanto - HARDNESS 7. Measure of the resistance to flow - VISCOSITY 8. Highly resistant borosilicate glass - TYPE I 9. USP classification of glass composed principally of silicon dioxide and boric oxide - TYPE I 10. Soda lime glass - TYPE III 11. When the drug or procedure should be used or performed cautiously - PRECAUTION 12. Used in closure of vials, transfusion fluid bottles, dropping bottles - RUBBER 13. Colligative Property : Osmotic Pressure, Freezing Point Depression , Vapor Pressure , Lowering Boiling Point Elevation, except - GAS LAW 14. Gas laws which states that for 1 mole of gas at a fixed temperature, the product of pressure (p) and volume (v) is constant - DALTON’S LAW 15. The pressure (p) of a given quantity of gas varies inversely with its volume (v) at constant temperature - BOYLE’S/MARIOTTE 16. PV = nRT - IDEAL/VAN DER WAALS 17. An in vitro procedure based on the gelling development of a pyrogen-contaminated injection, in 93 the presence of lysate on Horseshoe crab - LAL METHOD 18. KI3 is formed when iodine crystals are mixed with a solution of potassium iodide. The interaction governing this principle is - ION-INDUCED DIPOLE FORCES 19. Induced by the close proximity of a charged ion to a nonpolar molecule (l2 + KI) - ION-INDUCED DIPOLE 20. Expresses the relationship between the vapor pressure and the absolute temperature of a liquid CLAUSIUS- CLAPEYRON EQUATION 21. The pressure required liquefy the a gas at its critical temperature is termed as - CRITICAL PRESSURE 22. The following factors are affecting the solubility of solids in liquids EXCEPT - PRESSURE 23. (Archimedes + Boyle's law) to displace water - PYCNOMETER METHOD 24. Pressure - CHARLES 25. Safe dosing range - PHASE 1 26. Dose strength and schedules - PHASE 2 27. Alcoholic/ hydroalcoholic solutions prepared from vegetable drugs or chemical substances TINCTURES 28. Liniment type that is for massage; less irritating - OLEAGINOUS 29. Gel that absorbs but no ↑ in size - IMBIBITION 30. Kaopectate (kaolin + pectin + Bi subsalicylate) - ANTIDIARRHEAL 31. W/O EMULSIFYING AGENT LUMABAS 32. 33. Holds materials to be compressed where granules/powders are placed - HOPPER 34. Transfers/brings/distributes the granules/powders to the die - FEED SHOE/FEED FRAME 35. A part of the tablet press machine that determines the size and shape of the tablet - DIES 36. Adhesion of powders/granules to the die wall (due to excessive moisture) - STICKING 37. Adhesion of powders/granules to the punch faces (pinholes) - PICKING 38. A film defect that caused by over wetting or excessive film tackiness causes tablets to stick to each other or to the coating pan giving a "picked" appearance to the tablet surface - STICKING AND PICKING 39. Absorbs moisture - HYGROSCOPIC 40. Removal of material from the surface of the tablet & adheres to the punch face, term used to describe the surface material from a tablet that is sticking to and being removed from the tablet's surface by a punch - PICKING 41. Most common base for vaginal suppositories - GLYCERINATED GELATIN 42. Reversible gel-sol formation, term is used to describe gel and formation with no change in volume or temperature - THIXOTROPY 43. 44. Preferred container for parenterals - GLASS 45. Document with the result of all tests conducted on material to show compliance or non-compliance with the standard specifications - CERTIFICATE OF ANALYSIS 46. Recommended time period that a cosmetic product can be kept after its production - SHELF LIFE 47. May qs about dito: FLOWABILITY PROBLEM: ARCHING/BRIDGING - arch shaped obstruction above hopper outlet RAT-HOLING - discharge takes place only above the outlet 48. "Arching" or "bridging" and "rat-holing" are problems associated with weight variation of tablets, specifically - POOR FLOW 49. Sterilization method MOIST HEAT Autoclave or steam under pressure (121°C, 15psi, 15-20 minutes) MOA: protein coagulation BI: Bacillus stearothermophilus 50. Class sa areas COMPOUNDING AREA: CLASS 100 ASEPTIC FILLING AREA: CLASS 100 BUFFER AREA: CLASS 10,000 51. Drug to container - SORPTION 52. Emulsifiers: CATIONIC - Positively charged emulsifiers ANIONIC - Negatively charged when solvated as in sodium stearate or soap 53. A note that has the greatest molecular weight - BASE NOTES 54. Assist in pharmacy operations, supervised interactions with patients - PHARMACY ASSISTANT 55. May qs din about alcoholic and oleaginous liniment 56. 100% tincture - FLUIDEXTRACTS 57. Instability of suspension - CAKING 58. Accelerated studies - 6 MONTHS 59. Milling equipment for acid 60. MOP ng effervescent DRY/FUSION METHOD WET METHOD 61. RED: EXTERNAL USE Calamine Lotion Bentonite Methyl Salicylate Oil Turpentine Oil Emulsion WHITE: INTERNAL USE Aluminum Hydroxide Gel Cod Liver Emulsion Acacia Mucilage 62. Dangerous drug prescription shall be retained by the pharmacist for a period of - 1 YEAR 63. Compressed tablets that are coated with a substance resistant to gastric fluid and contain substances that are destroyed or inactivated in the stomach - ENTERIC COATED TABLETS 64. These are pharmaceutical equivalents that provide essentially the same therapeutic effect when administered to the same individuals in the same dosage regimens - THERAPEUTIC EQUIVALENTS 65. An example of a fatty or oleaginous suppository base – COCOA BUTTER AND WECOBEE BASES 66. The following preparations should have the auxiliary label “SHAKE WELL“ - MILK OF MAGNESIA, LINIMENTS, NYSTATIN SUSPENSION 67. The taking up of a liquid by a gel with an increase in volume is termed - SWELLING 68. Sweetening agent used in the manufacture of sugar-free chewable tablets - XYLITOL 69. A problem encountered in tablet film coating where there is uneven color distribution on the tablet surface - MOTTLING 70. SPANS and TWEENS belong to which group of emulsifier - NON-IONIC 71. The preferred diluents for chewable tablet since it has a pleasant ding sensation due to the negative heat of solution - MANNITOL 72. Compressed lozenges discoid shaped - TROCHES 73. Colloidal Clay that is used as a suspending agent (thixotropic) - BENTONITE CLAY 74. Assist in different aspects of pharmacy operation with very minimal degree of independence or decision-making, and without direct patient-interaction - PHARMACY AIDES 75. What adult vaccines can pharmacist administer - CERVICAL CANCER, FLU, COVID, PNEUMOCOCCUS 76. FUNCTIONS AND POWERS OF THE BOARD OF PHARMACY Administer and implement provisions of RA 10918 Promulgate rules and regulations to carry out provisions of RA 10918Prepare examination questions, scores, and ratingsRecommend issuance, suspension, or revocation or reinstatement of COR, PIC or STPs Administer oaths in accordance with RA 10918 Regulate and monitor the pharmacy practice Promulgate and prescribe the Pharmacists' Code of Ethics, and other guidelines Represent the pharmacy profession in all for a related to the pharmaceutical practice Investigate cases from violating RA 10918 Delegate hearing or investigate administrative cases Issue and promulgate guidelines on CPD Accredit standardized training programs for certification of detailmen Accredit Specialty Boards of Pharmacy 77. Percent weight in volume - NUMBER OF GRAMS OF CONSTITUENT IN 100ML OF PREPARATION 78. Closed containers fitted with a device that irreversibly indicated if the container has been opened - TAMPER-EVIDENT CONTAINERS 79. Ampoule sealing - TIP AND PULL SEALING 80. Plastic material is rigid and has good clarity. Use in blister packaging of capsules and tablets PVC 81. Tamper resistant qs - EXCEPT LINER YUNG SAGOT 82. Temperature necessary to liquefy propellant gas in aerosoL - -34.5°C to -40°C 83. Mixing large quantities - TUMBLING 84. Potent Drugs - GEOMETRIC DILUTION 85. How to liquify gas - DECREASE TEMPERATURE AND INCREASE PRESSURE 86. Chewable Tablets - MANNITOL 87. Coarse Dispersions are - EMULSION & SUSPENSION 88. Climatic zones - EITHER JAN SA DALAWA YUNG SAGOT ZONE III: HOT/DRY ZONE IV: HOT/HUMID 89. % of Glycerin in glycerites - 50% 90. Which is true about first order - 0.693/k 91. Castor oil - 3% 92. White ointment - WHITE PETROLATUM & WHITE WAX 93.

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