Clinical Hematology - Introduction to Blood PDF

Summary

This document provides a detailed introduction to blood characteristics, including its composition and various types of blood cells. It covers topics like red blood cells, white blood cells, and their functions within the human body.

Full Transcript

CLINICAL HEMATOLOGY BLOOD COMPOSITION TOPIC: INTRODUCTION TO BLOOD ENHANCEMENT CLASS INTRODUCTION TO BLOOD CHARACTERISTICS - Blood transports oxygen from lungs to tissue; clears tissues of carbon dioxide; transports glucose, pr...

CLINICAL HEMATOLOGY BLOOD COMPOSITION TOPIC: INTRODUCTION TO BLOOD ENHANCEMENT CLASS INTRODUCTION TO BLOOD CHARACTERISTICS - Blood transports oxygen from lungs to tissue; clears tissues of carbon dioxide; transports glucose, proteins and lipids; and moves wastes - Involves in Physiologic and Pathologic activity of the human body CHARACTERISTICS: Average volume of the human body: 5 liters pH of Blood: 7.35 – 7.45 Specific gravity: 1.045 – 1.065 Body temperature: 98.6-degree Fahrenheit More Viscous than water BLOOD CELLS Red in color Arterial blood: Bright red RED BLOOD CELL Venous blood: Dark red Anucleated Biconcave Contains HEMOGLOBIN SALMON PINK 7 – 8 um in dm FUNCTIONS - Transportation - Regulation NEUTROPHIL (PMN) - Protection 50% - 75% of the total peripheral WBCs in adults. COMPOSITION 10 to 15 um in dm Kills and phagocytose bacteria and other foreign debris PLASMA (55%: WHOLE BLOOD) 90% - Water 8 – 10% Solutes BUFFY COAT (4%: WHOLE BLOOD) Leukocytes Platelets PACKED RED BLOOD CELLS (41%: WHOLE BLOOD) Erythrocytes Fibrinogen (Non – Anticoagulated Tubes) A.R.B LYMPHOCYTE 20% - 40% of the circulating WBCs 7 – 10 um in diameter Effector and regulatory cells for adaptive immunity MONOCYTE 2% - 11% of circulating leukocytes 15 – 20 um Precursors of macrophages and other mononuclear phagocytic cells EOSINOPHIL 1% - 3% of the circulating WBCs in a non-allergic person 12 to 15 um in diameter Kill helminthic and other parasites; modulate local inflammation BASOPHIL 0% - 2% of circulating leukocytes 10 to 15 um in diameter Modulate inflammation, release histamine during allergy A.R.B CLINICAL HEMATOLOGY MCV (MEAN CELL VOLUME): - Measures the average size of red blood cells TOPIC: CBC PARAMETERS MCH (MEAN CELL HEMOGLOBIN): ENHANCEMENT CLASS REFERENCE RANGE CBC PARAMETERS - Hyperchromic - >32 pg RED BLOOD CELL COUNT: - Normochromic – 26 – 32 pg - Method used to detect medical conditions such as - Hypochromic - 36 g/dL - Normochromic – 32 – 36 g/dL - Hypochromic -

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