Summary

This document contains a set of chemistry study questions, covering topics such as dilutions of blood samples, dilutions of creatine, lab testing procedures, acid/base imbalances, electrolytes, and more. The study questions are formatted in a multiple-choice style.

Full Transcript

What is the dilution factor if 10 mL of sample is added to 190 mL of diluent? a.10 b\. 19 c\. 20 d\. 25 How much serum is required to make a 1 to 4 dilution with a total volume of 100.0 µL ? A\) 0.025 µL B\) 0.25 µL C\) 2.5 µL D\) 25 µL A patient\'s creatinine is outside the linear range o...

What is the dilution factor if 10 mL of sample is added to 190 mL of diluent? a.10 b\. 19 c\. 20 d\. 25 How much serum is required to make a 1 to 4 dilution with a total volume of 100.0 µL ? A\) 0.025 µL B\) 0.25 µL C\) 2.5 µL D\) 25 µL A patient\'s creatinine is outside the linear range of the analyzer; 10 µL of serum is added to 90.0 µL of diluent and the diluted sample is reanalyzed. The creatinine value of the diluted sample is 1.0 mg/dL. Which of the following creatinine values is correct? A\) 1.0 mg/dL B\) 10.0 mg/dL C\) 20.0 mg/dL D\) 100 mg/dL A serum creatine kinase is diluted 1/200 with a result of 50 U/L. What is the patient\'s actual creatine kinase result? A\) 50 U/L B\) 200 U/L C\) 1000 U/L D\) 10,000 U/L 5\. According to CLSI, the resistivity of clinical laboratory reagent water (CLRW) must be: A\) \> 100 milliamps. B\) \< 10 millivolts. C\) \> 10 MΩ ∙ cm. D\) \< 10 MΩ ∙ cm. Ion-exchange filters remove which of the following from a water source? A\) Ions to reduce the mineral content of water B\) Lead C\) Organic solvents. D\) Bacteria The anion gap is determined from which of the following groups of electrolytes? A\) Sodium, chloride, potassium, and calcium B\) Sodium, chloride, potassium, and HCO3- C\) Sodium, chloride, potassium, and phosphorus D\) TCO2, chloride, potassium, and magnesium Plasma osmolality can be calculated using which of the following? A\) Na + Cl + K + HCO3 B\) Na + 2(HCO3) + Urea nitrogen - glucose C\) 2(Na) + (glucose/18) + (BUN/2.8) D\) Glucose + 2(Na) - 2 (BUN) Measurement of sodium, potassium, and chloride are commonly performed in laboratories using which of the following? a\. Ion selective electrodes b\. Colorimetry c\. Photometry d\. Gas chromatography Which of the following electrolyte levels best correlate with plasma osmolality? b\. Chloride c\. Sodium d\. Calcium a\. Bicarbonate.Name the equation shown below. pH = pK\' + log cHCO3-/α x pCO2 A\) Anion gap transformation B\) Henderson-Hasselbalch equation C\) Isohydric shift algorithm D\) Negative log of the hydrogen ion concentration formulation 2.The specimen of choice for measuring blood pH, pO2, and pCO2 is: A\) Heparinized capillary blood. B\) Heparinized arterial blood. C\) Heparinized venous blood. D\) Serum. A patient\'s blood gas results are: pH= 7.48; PCO2 = 52 mmHg; HCO3- = 40 mEq/L; pO2 = 98 mmHg. These results are consistent with which of the following? Question options: Respiratory alkalosis Respiratory acidosis Partially compensated metabolic alkalosis Metabolic acidosis.A patient\'s blood gas results are as follows: pH = 7.25; dissolved CO2 = 1.8 mEq/L; HCO3- = 27 mEq/L. These results would be classified as: Question options: Metabolic acidosis. Metabolic alkalosis. Respiratory acidosis. Respiratory alkalosis..A patient\'s blood gas results are shown below: pH 7.32; pCO2 = 58 mm Hg; HCO3- = 28 mEq/L. These results indicate: A\) Respiratory acidosis. B\) Metabolic alkalosis. C\) Respiratory alkalosis. D\) Metabolic acidosis. 6Which of the following represents the compensatory response of the kidney and lungs to a patient who is in metabolic acidosis? Question options: The kidneys will increase bicarbonate reabsorption and the patient will begin to breathe very deeply and often gasp for air. The kidneys will decrease bicarbonate reabsorption and the patient will begin to hyperventilate. The kidneys will increase retention of hydrogen ions and the patient will begin to hold their breath for as long as possible. The kidneys will \"shut down\" in an attempt to retain all electrolytes and the patient will place a bag over their face to conserve oxygen and carbon dioxide..Which of the following compensatory mechanisms is correct for a patient in respiratory acidosis? Question options: Decrease respiration rate Increase the movement of electrolytes such as Na+ and H+ out of the cells and into the blood while increasing K+ from blood into cells. Decrease whole blood pCO2.Which of the following is the primary compensatory mechanism for metabolic acidosis? Hypoventilation Hyperventilation Bicarbonate excretion Retention of hydrogen ions.Which of the following is a derived blood gas parameter? Actual base excess pCO2 pO2 pH Which of the following carbohydrates is a polysaccharide? A\) Starch B\) Sucrose C\) Lactose D\) Glucose Glycolysis is: A\) The conversion of glucose into lactate or pyruvate and then CO2 and H2O. B\) The conversion of glucose to glycogen for storage. C\) The breakdown of glycogen to form glucose and other intermediate products. D\) The formation of glucose from noncarbohydrate sources. The only hormone that causes a decrease in blood glucose levels is: A\) Glucagon. B\) Thyroxine. C\) Insulin. D\) Parathyroid hormone. Glycogen is stored in the: A\) Pancreas. B\) Liver. C\) Spleen. D\) Gall bladder. Which form of diabetes usually manifests itself early in life, and is associated with ketosis, low insulin levels, and autoantibodies to islet cells? A\) Gestational B\) Type 1 C\) Type 2 D\) Congenital Which of the following is characteristic of type 2 diabetes mellitus? A\) High insulin levels B\) Ketosis C\) Obesity and physical inactivity D\) Juvenile onset Select the enzyme that is most specific for β-D glucose. A\) Phosphohexisomerase B\) Hexokinase C\) Glucose oxidase D\) Glucose dehydrogenase In the Hexokinase method for glucose determinations, the actual end product measured is the: A\) Amount of hydrogen peroxide produced. B\) NADPH + H+ produced from the reduction of NADP. C\) Amount of glucose combined with bromcresol purple. D\) Condensation of glucose with an aromatic amine The glucose concentration in normal cerebrospinal fluid is: A\) Usually less than 30 mg/dL. B\) 60-75% of the plasma glucose concentration. C\) Equal to the plasma glucose concentration. D\) Usually greater than 100 mg/dL All of the following are confirmatory of diabetes mellitus EXCEPT: A\) Fasting glucose greater than 126 mg/dL. B\) Urine glucose greater than 300 mg/dL C\) 2-hour postprandial glucose greater than 200 mg/dl. D\) 1- and 2-hour glucose tolerance values greater than 200 mg/dL.. What is the most probable acid/base imbalance in the patient described below? Respiratory alkalosis Respiratory acidosis Metabolic alkalosis Metabolic acidosis Which of the following carbohydrates is a polysaccharide? A\) Starch B\) Sucrose C\) Lactose D\) Glucose Glycolysis is: A\) The conversion of glucose into lactate or pyruvate and then CO2 and H2O. B\) The conversion of glucose to glycogen for storage. C\) The breakdown of glycogen to form glucose and other intermediate products. D\) The formation of glucose from noncarbohydrate sources. The only hormone that causes a decrease in blood glucose levels is: A\) Glucagon. B\) Thyroxine. C\) Insulin. D\) Parathyroid hormone. Glycogen is stored in the: A\) Pancreas. B\) Liver. C\) Spleen. D\) Gall bladder. Which form of diabetes usually manifests itself early in life, and is associated with ketosis, low insulin levels, and autoantibodies to islet cells? A\) Gestational B\) Type 1 C\) Type 2 D\) Congenital Which of the following is characteristic of type 2 diabetes mellitus? A\) High insulin levels B\) Ketosis C\) Obesity and physical inactivity D\) Juvenile onset 7\. The anion gap is determined from which of the following groups of electrolytes? 8\. Plasma osmolality can be calculated using which of the following? 9\. Measurement of sodium, potassium, and chloride are commonly performed in laboratories using which of the following? a\. Ion selective electrodes b\. Colorimetry c\. Photometry d\. Gas chromatography 10\. Which of the following electrolyte levels best correlate with plasma osmolality? Select the enzyme that is most specific for β-D glucose. A\) Phosphohexisomerase B\) Hexokinase C\) Glucose oxidase D\) Glucose dehydrogenase In the Hexokinase method for glucose determinations, the actual end product measured is the: A\) Amount of hydrogen peroxide produced. B\) NADPH + H+ produced from the reduction of NADP. C\) Amount of glucose combined with bromcresol purple. D\) Condensation of glucose with an aromatic amine The glucose concentration in normal cerebrospinal fluid is: A\) Usually less than 30 mg/dL. B\) 60-75% of the plasma glucose concentration. C\) Equal to the plasma glucose concentration. D\) Usually greater than 100 mg/dL All of the following are confirmatory of diabetes mellitus EXCEPT: A\) Fasting glucose greater than 126 mg/dL. B\) Urine glucose greater than 300 mg/dL C\) 2-hour postprandial glucose greater than 200 mg/dl. D\) 1- and 2-hour glucose tolerance values greater than 200 mg/dL. 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| | | | | | | | | | | | | | | | A) | | | | | | | | Vitamin | | | | | | | | K | | | | | | | | | | | | | | | | B) | | | | | | | | Vitamin | | | | | | | | B2 | | | | | | | | | | | | | | | | C) | | | | | | | | Vitamin | | | | | | | | C | | | | | | | | | | | | | | | | D) | | | | | | | | Vitamin | | | | | | | | A | | | | | | | | | | | | | | | | In | | | | | | | | fluores | | | | | | | | cence | | | | | | | | polariz | | | | | | | | ation | | | | | | | | immunoa | | | | | | | | ssay | | | | | | | | (FPIA), | | | | | | | | the | | | | | | | | electro | | | | | | | | ns | | | | | | | | in | | | | | | | | fluores | | | | | | | | cein | | | | | | | | molecul | | | | | | | | es | | | | | | | | chemica | | | | | | | | lly | | | | | | | | attache | | | | | | | | d | | | | | | | | to the | | | | | | | | hapten | | | | | | | | react | | | | | | | | in | | | | | | | | which | | | | | | | | of the | | | | | | | | followi | | | | | | | | ng | | | | | | | | manner? | | | | | | | | | | | | | | | | A) They | | | | | | | | do not | | | | | | | | spin at | | | | | | | | all. | | | | | | | | | | | | | | | | B) They | | | | | | | | spin | | | | | | | | 100 | | | | | | | | times | | | | | | | | faster | | | | | | | | than | | | | | | | | normal. | | | | | | | | | | | | | | | | C) They | | | | | | | | do not | | | | | | | | fluores | | | | | | | | ce. | | | | | | | | | | | | | | | | D) They | | | | | | | | fluores | | | | | | | | ce. | | | | | | | | | | | | | | | | Which | | | | | | | | of the | | | | | | | | followi | | | | | | | | ng | | | | | | | | is an | | | | | | | | example | | | | | | | | of a | | | | | | | | chemilu | | | | | | | | minesce | | | | | | | | nt | | | | | | | | compoun | | | | | | | | d? | | | | | | | | | | | | | | | | A) | | | | | | | | Fluores | | | | | | | | cein | | | | | | | | | | | | | | | | B) | | | | | | | | Luminol | | | | | | | | | | | | | | | | C) | | | | | | | | Acridin | | | | | | | | ium | | | | | | | | | | | | | | | | D) | | | | | | | | Cis-pla | | | | | | | | tinum | | | | | | | | | | | | | | | | Micropa | | | | | | | | rticula | | | | | | | | te | | | | | | | | enzyme | | | | | | | | immunoa | | | | | | | | ssay | | | | | | | | uses | | | | | | | | which | | | | | | | | of the | | | | | | | | followi | | | | | | | | ng | | | | | | | | enzymes | | | | | | | | to | | | | | | | | catalyz | | | | | | | | e | | | | | | | | the | | | | | | | | convers | | | | | | | | ion | | | | | | | | of the | | | | | | | | substra | | | | | | | | te, | | | | | | | | 4-methy | | | | | | | | lumbell | | | | | | | | iferyl | | | | | | | | phospha | | | | | | | | te | | | | | | | | to | | | | | | | | methylu | | | | | | | | mbellif | | | | | | | | erone? | | | | | | | | | | | | | | | | A) Acid | | | | | | | | phospha | | | | | | | | tase | | | | | | | | | | | | | | | | B) | | | | | | | | Alkalin | | | | | | | | e | | | | | | | | phospha | | | | | | | | tase | | | | | | | | | | | | | | | | C) | | | | | | | | Gamma-g | | | | | | | | lutamyl | | | | | | | | transfe | | | | | | | | rase | | | | | | | | | | | | | | | | D) | | | | | | | | Aldolas | | | | | | | | e | | | | | | | | | | | | | | | | Which | | | | | | | | of the | | | | | | | | followi | | | | | | | | ng | | | | | | | | immunoa | | | | | | | | ssays | | | | | | | | produce | | | | | | | | s | | | | | | | | a | | | | | | | | fluores | | | | | | | | cent | | | | | | | | molecul | | | | | | | | e, | | | | | | | | 4-methy | | | | | | | | lumbell | | | | | | | | iferone | | | | | | | | that | | | | | | | | serves | | | | | | | | as the | | | | | | | | detecto | | | | | | | | r | | | | | | | | compoun | | | | | | | | d? | | | | | | | | | | | | | | | | A) | | | | | | | | Micropa | | | | | | | | rticula | | | | | | | | te | | | | | | | | enzyme | | | | | | | | immunoa | | | | | | | | ssay | | | | | | | | | | | | | | | | B) | | | | | | | | Substra | | | | | | | | te | | | | | | | | labeled | | | | | | | | fluores | | | | | | | | cent | | | | | | | | immunoa | | | | | | | | ssay | | | | | | | | | | | | | | | | C) | | | | | | | | Enzyme | | | | | | | | multipl | | | | | | | | ied | | | | | | | | immunoa | | | | | | | | ssay | | | | | | | | | | | | | | | | D) | | | | | | | | Fluores | | | | | | | | cent | | | | | | | | polariz | | | | | | | | ation | | | | | | | | immunoa | | | | | | | | ssay | | | | | | | | | | | | | | | | Cushing | | | | | | | | \'s | | | | | | | | syndrom | | | | | | | | e | | | | | | | | is | | | | | | | | charact | | | | | | | | erized | | | | | | | | by | | | | | | | | which | | | | | | | | of the | | | | | | | | followi | | | | | | | | ng? | | | | | | | | | | | | | | | | A) | | | | | | | | Excess | | | | | | | | secreti | | | | | | | | on | | | | | | | | of | | | | | | | | pituita | | | | | | | | ry | | | | | | | | ACTH | | | | | | | | | | | | | | | | B) | | | | | | | | Adrenal | | | | | | | | insuffi | | | | | | | | ciency | | | | | | | | | | | | | | | | C) ACTH | | | | | | | | indepen | | | | | | | | dent | | | | | | | | | | | | | | | | D) ACTH | | | | | | | | depende | | | | | | | | nt | | | | | | | | | | | | | | | | What is | | | | | | | | the | | | | | | | | dilutio | | | | | | | | n | | | | | | | | factor | | | | | | | | if 10 | | | | | | | | mL of | | | | | | | | sample | | | | | | | | is | | | | | | | | added | | | | | | | | to 190 | | | | | | | | mL of | | | | | | | | diluent | | | | | | | | ? | | | | | | | | | | | | | | | | A. | | | | | | | | | | | | | | | |

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