Liver Disease Questions PDF

**What is a common cause of chronic liver disease that often leads to cirrhosis?** - A\) Hepatitis A - B\) Gallbladder stones - C\) Hepatitis C - D\) Pancreatitis **Answer:** C) Hepatitis C 2. **Which of the following is a characteristic feature of cirrhosis?** - A\) Normal liv...

**What is a common cause of chronic liver disease that often leads to cirrhosis?** - A\) Hepatitis A - B\) Gallbladder stones - C\) Hepatitis C - D\) Pancreatitis **Answer:** C) Hepatitis C 2. **Which of the following is a characteristic feature of cirrhosis?** - A\) Normal liver function - B\) Fibrosis and regenerative nodules - C\) Excessive bile production - D\) Increased liver size without scarring **Answer:** B) Fibrosis and regenerative nodules 3. **Portal hypertension in liver disease is primarily caused by:** - A\) Decreased blood flow to the portal vein - B\) Increased resistance to blood flow within the liver due to fibrosis - C\) Increased hepatic artery blood flow - D\) Reduced bile production **Answer:** B) Increased resistance to blood flow within the liver due to fibrosis 4. **Which complication of liver disease is characterized by low blood pressure, high cardiac output, and systemic vasodilation?** - A\) Cirrhotic cardiomyopathy - B\) Hepatorenal syndrome - C\) Hepatic encephalopathy - D\) Hepatopulmonary syndrome **Answer:** A) Cirrhotic cardiomyopathy 5. **What is the hallmark sign of hepatic encephalopathy?** - A\) Jaundice and low blood pressure - B\) Altered mental status due to neurotoxin accumulation - C\) Hypoglycemia and abdominal pain - D\) Severe anemia and shortness of breath **Answer:** B) Altered mental status due to neurotoxin accumulation 6. **Ascites, a common complication in liver disease, is primarily due to:** - A\) Portal hypertension and low plasma proteins - B\) Low cardiac output - C\) High hepatic vein pressure - D\) Increased vitamin K synthesis **Answer:** A) Portal hypertension and low plasma proteins 7. **In patients with liver disease, esophageal varices develop as a result of:** - A\) Increased bile secretion - B\) High intra-abdominal pressure - C\) Collateral circulation from portal hypertension - D\) Excessive vitamin K absorption **Answer:** C) Collateral circulation from portal hypertension 8. **Hepatorenal syndrome is primarily characterized by:** - A\) Elevated blood urea nitrogen (BUN) due to kidney dysfunction secondary to liver disease - B\) High sodium levels and increased urine output - C\) Low levels of prostaglandins - D\) Direct damage to the kidneys by hepatotoxins **Answer:** A) Elevated blood urea nitrogen (BUN) due to kidney dysfunction secondary to liver disease 9. **Which of the following markers is used to evaluate liver excretory function and is typically elevated in liver disorders involving bile flow obstruction?** - A\) Serum albumin - B\) Alkaline phosphatase - C\) Glucose - D\) Creatinine **Answer:** B) Alkaline phosphatase 10. **The triad of liver disease, unexplained hypoxemia, and intrapulmonary vascular dilation defines which liver disorder?** - A\) Cirrhotic cardiomyopathy - B\) Hepatorenal syndrome - C\) Hepatopulmonary syndrome - D\) Acute fatty liver disease of pregnancy **Answer:** C) Hepatopulmonary syndrome 11. **In chronic liver disease, hypoalbuminemia is typically due to:** - A\) Decreased bile production - B\) Reduced liver synthesis of plasma proteins - C\) Increased protein metabolism - D\) Increased renal protein clearance **Answer:** B) Reduced liver synthesis of plasma proteins 12. **Which test is commonly prolonged in liver disease due to the liver's inability to produce certain clotting factors?** - A\) Serum creatinine - B\) Alkaline phosphatase - C\) Prothrombin Time (PT) - D\) Glucose test **Answer:** C) Prothrombin Time (PT) 13. **Nonalcoholic fatty liver disease (NAFLD) is most closely associated with which of the following conditions?** - A\) Alcohol consumption - B\) Metabolic syndrome - C\) Viral hepatitis - D\) Hemolysis **Answer:** B) Metabolic syndrome  **Which of the following is considered the end-stage result of chronic liver disease?** - A\) Hepatitis - B\) Ascites - C\) Cirrhosis - D\) Hepatopulmonary syndrome **Answer:** C) Cirrhosis  **Portal hypertension occurs primarily as a result of:** - A\) Increased portal vein oxygenation - B\) Decreased hepatic artery blood flow - C\) Increased resistance to blood flow in the liver due to fibrosis - D\) Low systemic blood pressure **Answer:** C) Increased resistance to blood flow in the liver due to fibrosis  **Hepatic hydrothorax, a complication of cirrhosis, results from:** - A\) Blood flow diversion from the liver - B\) Fluid movement from the abdominal cavity to the pleural space - C\) Elevated blood ammonia levels - D\) Increased kidney filtration rates **Answer:** B) Fluid movement from the abdominal cavity to the pleural space  **In chronic cholestatic liver disease, impaired bile flow and increased biliary pressure can lead to:** - A\) Portal vein thrombosis - B\) Hepatocyte destruction and possible infection - C\) Enhanced clotting factor production - D\) Reduced inflammation **Answer:** B) Hepatocyte destruction and possible infection  **Which vitamin deficiency is most likely in patients with chronic cholestatic liver disease?** - A\) Vitamin C - B\) Vitamin A - C\) Vitamin B12 - D\) Vitamin K **Answer:** D) Vitamin K  **Which liver disease is associated with hemolysis, elevated liver enzymes, and a low platelet count, particularly in pregnancy?** - A\) Cirrhosis - B\) Primary biliary cholangitis - C\) HELLP syndrome - D\) Portal hypertension **Answer:** C) HELLP syndrome