Summary

This document contains questions related to diagnostics, disease-associated markers, and malaria. It asks about the ideal diagnostic for an analyte or disease-associated biomarker, and suitable diagnostics for a treatable disease known to cause liver damage.

Full Transcript

Unit 4. Quiz 1 Q1. Match the following diagnostics with the best outcome/need. You will use each concept once when matching. A. High sensitivity and low specificity B. High sensitivity and high specificity C. Low sensitivity and low specificity D. Low sensitivity and high specif...

Unit 4. Quiz 1 Q1. Match the following diagnostics with the best outcome/need. You will use each concept once when matching. A. High sensitivity and low specificity B. High sensitivity and high specificity C. Low sensitivity and low specificity D. Low sensitivity and high specificity ______ An ideal diagnostic for any analyte or disease-associated biomarker ______ Acceptable for an analyte or disease-associated biomarker when no other test exists ______ Acceptable (but not ideal) for an analyte of a disease-associated biomarker for a disease that is communicable ______ Acceptable (but not ideal) for an analyte of a disease-associated biomarker for a disease with no treatment Q2. Which diagnostic would be acceptable (if not ideal) for an analyte of a disease-associated biomarker for a disease that is treatable but the treatment is known to cause liver damage? a. High sensitivity and low specificity b. Low sensitivity and low specificity c. Low sensitivity and high specificity Q3. Suppose an antibody-based test for detecting malarial parasite-associated proteins has a specificity of 82% and a sensitivity of 75%. What is the minimal number of samples you would need to test in the lab to get 100 false negatives and 50 false positives?

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