Practice Questions Cell Biology PDF

[Practice questions lectures/practicals Van Weering] 1\. The chromatids are attached to microtubules by kinetochore during the prometaphase. To what part of the chromosome is kinetochore binding in this process? a\. A centriole b\. A centromere c\. A centrosome d\. A centroplast 2\. Axons are...

[Practice questions lectures/practicals Van Weering] 1\. The chromatids are attached to microtubules by kinetochore during the prometaphase. To what part of the chromosome is kinetochore binding in this process? a\. A centriole b\. A centromere c\. A centrosome d\. A centroplast 2\. Axons are often wrapped by myelin, which comprises multiple membranes. What is the function of this structure? a\. insulation to prevent cytosol leakage b\. insulation to prevent warmth escape c\. insulation to prevent organelle leakage d\. insulation to prevent membrane potential diffusion 3\. What are essential hallmarks of all cells? a\. Cells are composed of cytosol containing organelles. b\. Cells are composed of cytosol containing biomolecules. c\. Cells are composed of organelles attached to the cytoskeleton. d\. Cells are composed of genetic material that is divided over daughter cells. 4\. APC/C is an important protein in the cell cycle. What is the role of APC/C? a\. APC/C regulates the metaphase/anaphase checkpoint by degradation of the separase enzyme. b\. APC/C triggers DNA duplication and cyclin break down. c\. APC/C activates the separase enzyme and triggers degradation of all cyclins. d\. APC/C regulates the G1/M-phase checkpoint by degradation of the separase enzyme. 5\. The cross sections above are all made from the geometrical figure\.... a\. cylinder b\. tetrahedron c\. cuboid d\. cone 6. In the EM picture of bone tissue above, three areas are indicated. What are these structures? a\. 1 = osteoblast, 2 = osteoclast, 3 = osteocyte b\. 1 = osteoclast, 2 = osteocyte, 3 = bone matrix c\. 1 = osteocyte, 2 = osteoblast, 3 =bone matrix d\. 1 = osteocyte, 2 = osteoclast, 3 = osteoblast 7\. Which of the following processes take place during the G1 phase of the cell cycle? Choose the best fit answer. a\. Synthesis of new DNA b\. Synthesis of new organelles c\. Synthesis of new centrosomes d\. Synthesis of the midbody 8\. What is the function of S/Cdk? a\. Starting the anaphase b\. Starting of apoptosis c\. Starting of DNA replication d\. Starting of profase 9\. In which branch of the tree of life do you find multicellular organisms? a\. Archaea b\. Bacteria c\. Eukaryotes d\. Prokaryotes 10. Which organelle is indicated by number 1 in the EM picture above? a\. Endoplasmic reticulum b\. Endosome\ c. Golgi apparatus d\. Mitochondrion 11. At which checkpoint numbered in the picture above are all cyclins degraded? a\. 1\ b. 2\ c. 3\ d. cyclins are not degraded, they are dephosphorylated. 12. In the electron microscope collagen fibres show a striped pattern, what causes this pattern? a\. This is caused by the actin and myosin association in these fibres.\ b. This is caused by the binding of calcium to mature collagen fibres.\ c. This is caused by the overlap of tropocollagen elements\ d. This is caused by the stretching of collagen fibers, it is an artefact of the EM preparation. 13\. In the TED talk by professor Clevers two advantages are mentioned of stem cell therapy. Which ones are these? a\. You can transplant part of an organ and you can use stem cells from the patients themselves.\ b. You can transplant part of an organ and you do not have to treat patients with medication.\ c. You do not have to perform an operation on the patient and you do not have to treat patients with medication. d\. You do not have to perform an operation on the patient and you can use stem cells from the patients themselves. 14\. Put these structures in order from big (first) to small (last) a\. mitochondrion, nucleus, ribosome, water molecule b\. nucleus, mitochondrion, ribosome, water molecule c\. nucleus, mitochondrion, water molecule, ribosome nucleus, d\. ribosome, mitochondrion, water molecule 15\. What component is part of an electron microscope but is not present in light microscopes? a\. objective lens b\. condensor lens c\. eye piece d\. none of these options [Practice questions Smit] 16\. In a desmosome are located: \(a) connexins \(b) keratin \(c) cadherins \(d) hyaluronic acid   17\. With which statement do you agree? \(a) ATP hydrolysis plays a similar role in actin and tubulin polymerisation \(b) GTP hydrolysis plays a similar role in actin and tubulin polymerisation \(c) ATP and GTP do not play a role in the stabilization of one of these \(d) GTP stabilizes tubulin polymerisation   18\. Integrin molecules \(a) bind to intermediate filaments \(b) are involved in connecting actin filaments to collagen \(c) make the connection of intermediate filaments to the cell membrane \(d) are directly connected to collagen.   19\. When a G-protein binds to an activated receptor, then: a\. the receptor gets phosphorylated b\. the G-protein gets activated c\. the GTP on the G-protein converts to GDP d\. cAMP is formed   20\. The length of an actin filament is determined by: \(a) the voltage difference between -- and + end \(b) capping proteins \(c) the number of connected actin monomers \(d) de breakdown at the -- end [\ ] [Practice questions Luirink] 21\. The Signal Recognition Particle (SRP): 22\. The chaperone PDI is kept in the endoplasmic reticulum (ER) by: A. **A C-terminal KDEL signal** D A sugargroup (glycosylation)   23\. Pinocytosis is:   24\. Mannose-6-phosphate is a targeting signal for:   25\. Most mitochondrial proteins are made: B In the cytosol **C In the nucleus and are actively imported in the matrix** D At the ER **[Answers]** 1B 2D 3B 4C 5C 6B 7B 8C 9C 10D 11C 12C 13A 14B 15D 16C 17D 18B 19B 20C 21D 22A 23B 24A 25B