Pharma Variants 2 PDF

WIAIRMAINIT 1 1. Beta blocker stimulating 2. What we use for treatment of angina attack Nitrates/Beta blockers / Cachannel blockers 3. Benefit of using i. m....

WIAIRMAINIT 1 1. Beta blocker stimulating 2. What we use for treatment of angina attack Nitrates/Beta blockers / Cachannel blockers 3. Benefit of using i. m. - 4. Which antibiotics is used for intracellular organisms ? Macrolides. 5 Therapeutic index is Ratio between lethal and mean effective closes G. Which of the following is a side effect of Clonidine? D ry mouth/drowsiness and depression/ hypertensive attacks after 7. ADRs of SSRIs cessation serotonin Syndrome/sexual dysfunction 8. Which antiepileptic drug is inducer an enzyme Phenytoin/Phenobarbital ?. 9 which of the following dirretic is used as combined drug for hypertension Hydrochlorthiazide effect for ? 10. Analgesic antipyretic , , analgesia used - 11 - Q not know but > - these are true : · it's enzyme should be indrcer. might have been taken after Carbamazepine the Q meal 12 Diuretic combined for ↓ cell membrane. used as drug hypertension · permeability Spiranolactone · P450 inoucer. Indirect 13 anticoagulant oral use : Acenocoumaroum (Sintrom) 14. Benzodiazepines potentiate the effect of Alcohol/opioid analgesics WIAIRTAINIT 2 1. Amiodarone ADRs hypo-hyperthyroidism/photosensitivity/peripheral neuropathy/hepatotoxicity 2. Opioid antispasmodic effect Pethioline (Lydol) 3. NSAIDS used for headache/arthritis/tooth ache 4. MOA of fluoroquinolones inhibition of topoismerase 11 and IV. 5 Bacteriostatic antibiotic macrolides non combined sulfonamides/amphenicals/tetracyclines / Lincosamides. 6 Neuroleptanalgesia Fentanyl + Droperido ADRS of. 7 Methyldopa drug induced parkinson's 8. MOA of Benzodiazepine auxiolytics ↑ effectiveness of GABA. 9 Drug for vitB12 Cyan cobalamin (megaloblastic anemia. Orally /i m(. 10 Drug suspensions and oil solutions route of administration · ral/i m.. / subcutaneous 11 Antagonists of non-polarizing muscle relaxants anticholinesterases (Neostiguine/Endriohonium) 12. Lidocaine as antiarrhythmic administered Orally /i v.?. 13. Cardiac glucosides MOA Positive inotropic/negative chronotropic/negative dromotropic/positive bathmotropic 14 Potentiation is - 15. Antianginals MOA conversion into nitric oxide ↑ CAMP produce smooth muscle relaxation WIAIRMAINT 3. 1 Antihypertensive drugs are : ACE inhibitors 2. An adverse effect of beta-blockers is : Peripheral edema. 3 Which drug increases dopamine levels in the CNS and is used for Parkinson's disease treatment : Levodopa 4. Antagonist of benzodiazepines is : Flumazenil. 5 Anticholinesterase agents are used in : Alzheimer's disease 6. An adverse drug reaction of ay-adrenoblockers is : Orthostatic collapse at first intake 7. An adverse sulfonamides is : drug reaction of Crystalluria 8. Which is the first choice for treatment of status drug the epilepticus : Diazepam. A host factor 9 influencing the action and effect is : , drug Genetic polymorphism which of the 10 following effects belong to Paracetama Analgesic Il. Opioid analgesics affecti Inflammatory pain/malignant ?. In 12 pernicious anemia VitBiz should be administered Intramuscularly 13. which of the listed is an antiplatelet agent drugs Clopidogre( 14. A of leading adverse drug reaction atypical antipsychotics is : "Steal" phenomenon. The antimicrobial action 15 of sulfonamides occurs through : Blocking the of folic acid Synthesis WAIRMAINT 4 ↓ apparent volume of drug. The volume of distribution (Va) is : 1 distribution in various compartements Plasma unbound drug equalled , to the volume of physiological liquids , 2. An inhibitor is Plasma bound drug enzyma : Sodium valproate/Topiramate. 3 Macrolides are Effective against mycoplasma , Legionella Chlamydia , 4. The mechanism of action of Levetiracetam (Keppra) is : Binding of SVzA Protein in synaptic rescicles. 5 Opioid analgesic are used in : Hemorrhagic shock 6. What is a drug's therapeutic margin ? The difference between minimum toxic and minimum therapeutic 7. Which of the following can be used during pregnancy ? closes Peniciliu 8. Bilirubin encephalopathy in newborn children can be observed administration of during : Sulfonamides. ADRs of 9 paracetamol include : intestitial rephritis/hepatotoxicity 10 MOA metformin - 11. Therapeutic effect of glucocorticoids Anti-inflammatory/immuno suppresive/antiolergic 12. Co trimethazone uses - 13. Barbiturates bind to what ? - 14. Fluoroquinolones -. Adverse 15 drug reactions of tricyclic antidepresants are : Anticholinergic effect/seitures/cardiotoxicity Carrythmia/ Av conduction  WIAIRMAINT 5 1 more 1. Indications For b blockers -. 2 Indications for cholinolytics - 3. Correct statement about Pethioline spasmolytic effect on smooth muscle/shorter action than morphine 4. ADRs of tetracycline hepatotoxicity /t bone growth in children/yellow-brown teeth. 5 of MOA atypical antipsychotics block of 5-HT2 receptors/block of postsynaptic Da receptors > D2. 6 Antidote for benzodiazepiues Flumazenik 7. 4th Gen cephalosporius Cefepim/Cefpirom. Clonidine 8 -. 9 Indications for Acetylcholine Paralytic ileus/atropine intoxication ! tubocuraniue antidote 10. ADRs Rifampicin hepatotoxicity/orange-red crive 11 Drugs to use in neuropathic pain Pregabalin/ Gabapentin 12. ADRS Ca Channel antagonist non DHP Brady Cardia/ constipation/HF * 13. MOA of M Cholinolytics Stimulation of brouchii by parasympathetic fibers of vagr nerve brochoconstriction + secretion of mucus 14 *. Which drug has ADR of ototoxicity thiazide , Loop diuretics , furosemide aminoglycoside , * not sure if from that particular variant WIAIRMINIT G * I can't remember which one was available in the answers). 1 Antidote for heparin is Protamin sulfas Adverse of statins 2. drug reactions are Hepatotoxicity/myositis/GIT disorders A. 3 Chloramphenicol is effective against Gram () bacteria 4. Antibiotics with high activity against Helicobacter pylori are : Clarythromycin. 5 which of the following enteral routes of drug administration avoid the first pass metabolism in the liver : Sublingual 6. The analgesic effect of analgesics-antipyretics is due to: Influencing extero- and proprio receptors for pain 7. Adverse reactions of I receptor drug angiotensiv antagonists are : Hyperkalemia. 8 Pharmacologic effects of cardiac glycosides are Positive inotropic/negative chronotropic/negative dromotropic/positive bathmotropic *. Which 9 appropriate for of antiarrhythmic drug is treatment supraventricullar arrhythmias Verapamil 10 What are the adverse drug reactions of the inhaled corticosteroids : Oral candidiasis Which used antidote in case of 11. mucolytic agent can be as acute paracetamol intoxication ? Acetyicysteine. An effect of 12 Norepinephrive is : Peripheral vasoconstriction 1.3. Diuretic given in chronic renal failure : Furosemide 14. Adverse drug reaction of nitrates : organic Tolerance 15 Combined sulfonamides are. Bactericidal drugs WIAIRMINIT 7. 1 Adverse drug reaction of 6-adrehomimetic is : Hyperglycemia 2. which dirretic is used when the creatinine clearance is equal to or lower than ?...? Furosemide. An adverse 3 drug reaction of quindones is : Damage to the articular cartilages in children and addescents. An adverse 4 drug reaction of benzodiazepines with a hypnotic effect is : Drug tolerance and dependance. Central 5 muscle relaxants are used to treat Spasmus of the skeletal of muscles as a result CNS damage 6. For megaloblastic (permiscious) anemia the drug of choice is : Cyancobalamin (Vi + Biz) 7. Adverse drug reaction of ACE inhibitors is : Hyperkalemia. A 8 characteristic feature of Fentanyl is : Stronger analgesic than morphine. Which 9 drug has an antiseptic and hemostatic effect : Solutio hydrogeni peroxydi diluta 10. Macrolides are : Effective against mycoplasmas Legionella chlamydia , , 11 The main indication for the use of antimuscarinic drugs is Chronic broncho obstructive diseases. All the 12 following are adverse effects of Aspirin except : Hypotension. A is 13 mucolytic agent : Acetyicysteine 14. A pharmacological effect of Chlonidine is : Antihypertensive 15 An adverse reaction of dihydropyridine calcium is :. drug antagonists of the ankles Swelling WIAIRMINIT 8 4 more & Drug induced Parkinson's * Methyldopa/Amioarone/Haloperida 2 ADMs of He blockers sedation(dry mouth/ Fatigue/dizziness 3 Peripheral effects of Local anesthetics - 4 Valproates MOA ↓ cell membrane permeability to calcium T-channels/enzyme inhibitor 5 which drug has autogenic effects - 6 Neurotropics ↑ cognitive functions , augument effect of opioids 7 Action of cardiac glycosides inhibition of the NatKT-ATPase 8 Selective Cox2 Aspirin/Celecoxib/Indomethacin WIAIRMINIT9 1. ADRS of Mitric oxide hypotension tolerance flashing , , headache , tachycardia 2. Estrogen deficiency signs Diabetes or insulin resistance 3. ADRs of phenotoin Headaches and drowsiness 4. Competitive antagonists Serotoninland aldosterone ? ). 5 ADRs of Metformin Lactate acioosis. 6 ADRS Browio salt irritation (rhinitis , ache )... 7. ADRs of Antipsychotics Parkinsonism/hypertensive crisis 8. Therapentic margin The difference between minimum toxic and minimum therapeutic 9. MAOA antidepresant/Which drug is reversible MAO ? closes # ethoclobamine 10. Typical antiepileptic muscarinic 11. Clearance theoritical volume of plasma from which drug is completely removed in unit time 12. MDA of ACE inhibitors bind of ACE ↓ of concentration to zinc ion - > angioteusin Il 13. NSAIDS activity analgesia ↓ inflammation ? 14. Antagonist to opioids Noloxone 15 Corticosteroids. Anti inflammatory W/AIRM/AINIT 10 5 more 1. ADRs of penicilin Allergic reactions/anaphylactic shock/disbacterisis. 2 Nystoltin use Antifungal antibiotic. 3 Opioid antitussive effect Codeine 4. ACE inhibitors antiarrhythmic effect -. 5 Antihypertensive - 6. Which is 24a Gen cephalosporiu ? Cefaclor/Cefamando 7. What is pharmakokinetics? Absorption / Distribution/ Biotransformation/ elimination WIAIRMAINT 11 1. Cardiac glycoside effect Positive bathmotropic 2. ADRS Of NDHP CCB Bradycardia 3. Ni cholinoreceptor location Skeletal musche 4. Reversible MAO - A inhibitors -. 5 What group of drug is used to treat parkinsonian syndrome Dopaminergic/antimuscarinic drugs/RVodopa 6. Local anesthetic fast action and low concentration in which no types ? Myclinated. 7 Drugs in asthma attack a-agonists/82 adrehergic agonists Salbutamo. Treatment 8 for trigeminal neuralgia Larbamarepine 9. Anticoagulant Clopioogrel 10. Macrolides example Azythromycin (Azatril)/Roxithromycin (Rulid)/Clarithromycin (Klacid) 11. Advantages ofOral administration - 12. ADRs of tetracyclines hepatotoxicity /t bone growth in children/yellow-brown teeth. 13 Benzodiazepines contraindications Myasthenia gravis/sleep aprea/ pregnancy/severe respiratory 6) isease Which 14. drug t absorption of sulfonamides penicilin ?  WIAIRMAINT 12. 1 Opioias antidote Naloxone. 2 Antiagina drugs Nitrates/Beta blockers / Ca channel blockers 3. Function of opioids and NSAIDS Analgesia ?. Definition of 4 clearance theoritical volume of plasma from which drug is completely removed in unit time. 5 Direct antagonists -. 6 Antiarrhythmic drugs Verapamil/Adenosine/Amiodarone/Proprandol/ Propafenone/Lidocaine/ Quinidine 7. Drug induced Parkinson's sulfate * Methyldopa/Amioarone/Haloperida 8. Amiodaron antiarrhythmic drug is in which class ? Class III 9. Iron absorption in duodenum/t with antacial drugs/ferro ions predominantyed 10. Anti fungal drug Nystatin/Amphotericine B II. Vit function Synthesis of clotting factors 11 VII IX X (fatsoluble) 12. ADRS Ca Channel antagonist non DHP Brady Cardia/ constipation/HF * 13. MOA of ACE inhibitors ↓ angiotensin II ↑ bradykinin Levels , * 14. Digoxin blosage 0, 25 mg * 15. ADRs Nitrous Oxide hypotension tolerance , flashing , headache , tachycardia * not sure if from that particular variant  W/AIRMAINT 14 1 more 1. Antiemetics P. Hydrochloridum 2. Toxicity Overdose 3. Phase I drug metabolism may or may not involve cytochrome P450 system phase I reaction convert lipophilic moucules to more polar ones includes alcohol dehydrogenation , amire oxidation hydrolysis , 4. ADR penicilin Allergic reactions/anaphylactic shock/disbacterisis. 5 Selective inhibitor NSAIDS G. Valproate doesn't affect 6) IT ? because in ADRs-> ↑ weight hair loss , , hepatotoxicity but NO 7. Peripheral effect constipation Morphine 8. Cephalosporin 4th Gen Cafepim/Cefpirom 9. Drug enzyme inducer Phenytoin/Phanobarbital/Ketoconazole/Metronidazole/Rifampicin Carbamazepine * 10. Ademosine what class V * II. Prolonged nitroglycerin intake tolerance * 12. Augiotensin blocker ADR dry cough/hypotension/headache * 13. MOA of NSAIDS Inhibitor of Cox enzyma for hypertensive crisis A 14. Drug choice Chlonidine * not sure if from that particular variant 13 15... ,