Phagocytosis Post Lab 1 PDF

MIDTERM POST-LAB 1 MICROBIOLOGY PHAGOCYTOSIS Appears pink to lilac Engulfment and destruction of microo...

MIDTERM POST-LAB 1 MICROBIOLOGY PHAGOCYTOSIS Appears pink to lilac Engulfment and destruction of microorganism or damage Nuclei – purple blue cells Cytoplasm – pinkish tan Discovered by: Ellie Metchnikoff Function: primary WBC that functions in phagocytosis o Transparent starfish larvae Granulocytes – presence of granules o He introduced foreign 2. Eosinophil material Sphere shape that can be seen in peripheral blood smear o He noted the presence of 1-5% moving cell trying to get rid 12-15mm of that foreign material They only increase if there is parasitic invasion or inflammation or allergic reaction Major Events: Larger than neutrophil 1. Initiation Cytoplasm As a result of tissue damage § Strong affinity to acid dye Either be due to trauma or result of microorganism § Color: orange to reddish multiplication § Granules: Round or oval 2. Chemotaxis § They are evenly distributed Movement of cell in a certain direction Bilobed – there is only 2 lobe presents Substances that will direct the phagocytic cells into the Spectacle shape lobe site of inflammation Function: Without the presence of chemotaxis, the cells will have Less efficient phagocytosis (because they lock random movement; no organize movement lysozyme) 3. Engulfment § Through membrane invagination § Neutralized basophil and mast cell products Will ingest the foreign material/microorganism § Kill parasites 4. Digestion Presence of granules killing of pathogenic microorganism 3. Basophil Rare; cannot be seen in peripheral blood smear Different Steps in Phagocytosis: It will only increase in allergic reaction 1. Adherence Population is