Pathology PYQs Paper 2 PDF
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Uploaded by BrainyHeliotrope2991
2024
KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES
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This is a collection of pathology past papers for the second-year MBBS students from Kaloji Narayan Rao University of Health Sciences, covering multiple choice questions, long answer questions, short answer questions, and very short answer questions. Topics include various pathological conditions and diseases.
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# KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES ## MBBS SECOND YEAR DEGREE EXAMINATIONS: FEBRUARY, 2024 ### PATHOLOGY #### Paper -II **Time:** 3 Hours **Max Marks:** 100 **Note:** Answer all questions Give Diagrammatic representation wherever necessary ### Multiple Choice Questions: 1. GIT...
# KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES ## MBBS SECOND YEAR DEGREE EXAMINATIONS: FEBRUARY, 2024 ### PATHOLOGY #### Paper -II **Time:** 3 Hours **Max Marks:** 100 **Note:** Answer all questions Give Diagrammatic representation wherever necessary ### Multiple Choice Questions: 1. GIT malignancies are NOT associated with: - H pylori infection - Familial polyposis - Epstein Barr virus - Amoebiasis 2. Which virus is NOT transmitted parenterally - Hepatitis B virus - Hepatitis C virus - Hepatitis G virus - Hepatitis E virus 3. Atherosclerosis initiation is mediated by - Smooth muscle - Tunica Adventitia - Tunica media - Endothelium 4. Most common type of renal stone is, - Calcium oxalate - Uric acid - Ammonium magnesium phosphate - Cystine 5. Risk of Endometrial carcinoma is the highest in: - Endometrial hyperplasia with atypia - Simple hyperplasia - Endometrial hyperplasia without atypia - All of the above 6. Triad of Graves disease consists of the all EXCEPT: - Hyperparathyroidism - Disease of males - Ophthalmopathy with exophthalmos - Pre tibial myxoedema 7. Patients of myasthenia gravis have the following features except: - There is reduction in Acetylcholine Receptors (AChRs) - Thymic hyperplasia has a risk in its aetiology - Majority of patients have anti-AChR antibodies in their serum - Is an example of type III Hypersensitivity reaction 8. Not a Sex cord tumor of ovary is - Granulosa cell tumor - Thecoma - Dysgerminoma - Leydig cell tumour 9. Feature of HPV infection in a PAP smear is - Acanthosis - Koilocytosis - Parakeratosis - Hyper granulosis 10. Bone Tumor with small round cell morphology on histology is - Ewings sarcoma - Chondrosarcoma - Osteoclastoma - Osteoblastoma ### Long Answer Questions: **2 x 15 = 30** 11. Define and Classify Pneumoconiosis. Discuss the pathology and complications of Asbestosis. 12. Classify Bone Tumours. Discuss Osteogenic Sarcoma. ### Short Answer Questions: **7 x 6 = 42** 13. Good Pastures Syndrome. 14. Cor Pulmonale. 15. Linitis plastica. 16. Retinoblastoma. 17. Lung Abscess. 18. Hashimoto's Thyroiditis. 19. Gout. ### Very Short Answer Questions: **6 x 3 = 18** 20. Meckel's Diverticulum. 21. Psammoma bodies. 22. Corpora Amylacea. 23. Wilsons disease. 24. Microscopy of Schwannoma. 25. Schiller Duval body. # KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES ## MBBS SECOND YEAR DEGREE EXAMINATIONS: FEBRUARY, 2024 ### PATHOLOGY #### Paper -II **Time:** 2 Hours **Max Marks:** 40 **Note:** Answer all questions Give Diagrammatic representation wherever necessary ### Write an essay on the following: **1 x 10 = 10** 1. Define and classify Cirrhosis. Describe the morphological features of Alcoholic Liver Disease. ### Write a short note on the following: **5 x 4 = 20** 2. Pleomorphic Adenoma. 3. Malignant Melanoma. 4. Pathogenesis and complications of Bronchiectasis. 5. Adult Polycystic Kidney Disease. 6. Papillary Carcinoma Thyroid. ### Write briefly on the following: **5 x 2 = 10** 7. Define Aneurysm. Mention its types. 8. Classification of Hodgkin Lymphoma. 9. Fibro Adenoma. 10. Kidney changes in Malignant Hypertension.. 11. Microscopy of Schwannoma. # KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES ## MBBS SECOND YEAR DEGREE EXAMINATIONS: MARCH, 2023 ### PATHOLOGY (NEW REGULATION) #### PAPER-II **Time:** 3 Hours **Max Marks:** 100 **Note:** Answer all questions Give Diagrammatic representation wherever necessary ### Write an essay on the following: **2 x 15 = 30** 1. Classify Bone Tumours. Discuss the etiology and pathogenesis of Bone tumours. Describe in detail types, Clinical features, Microscopy and radiological features of Osteosarcoma. (4+3+3+5) 2. Discuss clinical features, etiopathogenesis of Acute Rheumatic Fever. Describe the changes in the heart in Acute Rheumatic Fever. List the outcomes and complications of Acute Rheumatic Fever. (3+4+4+4) ### Write a short note on the following: **8 x 5 = 40** 3. Chronic Pancreatitis. 4. Etiopathogenesis of Cervical Carcinoma. 5. Seminoma. 6. Morphology of Renal Cell Carcinoma. 7. Pathogenesis of type II Diabetes Mellitus. ### Write briefly on the following: **10 x 3 = 30** 8. Leiomyoma-Sites, gross and microscopy. 9. Pathogenesis of Acute Respiratory Distress Syndrome (ARDS). 10. Etiopathogenesis of Colonic Carcinoma. 11. Complications of Cirrhosis. 12. List three Precancerous Lesions of Penis. 13. Morphology of Chronic Pyelonephritis. 14. Types of gall stone. 15. Risk factors for endometrial Carcinoma. 16. Pathogenesis and complications of Bronchiectasis. 17. List the complications of Lung Abscess. 18. Morphology of Warthin's Tumour. 19. Berry Aneurysm. 20. Stages of Lobar Pneumonia. # KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES ## MBBS SECOND YEAR DEGREE EXAMINATIONS: MARCH, 2023 ### PATHOLOGY (OLD REGULATION) #### PAPER - II **Time:** 2 Hours. **Max Marks:** 40 **Note:** Answer all questions. Give Diagrammatic representation wherever necessary. ### Write Essay on the following question: **1 x 10 = 10** 1. A Male patient aged 45 years gives a history of severe Chest pain radiating to left arm and sweating, SOB. He is a known smoker, alcoholic and has a family history of Hypertension. - What is your Diagnosis? - Describe the pathophysiology of the Disease. - What are the laboratory investigations to be done to arrive at the Diagnosis. - Discuss the complications of the Disease. (1+3+3+3) ### Write a Short note on the following: **5 x 4 = 20** 2. Chronic Hepatitis. 3. Precancerous lesion of Penis. 4. Pleomorphic Adenoma. 5. Emphysema. 6. Inflammatory Bowel Disease. ### Write briefly on the following: **5 x 2 = 10** 7. Ewing's sarcoma. 8. Mention four types of Gall Stones. 9. Write four histological types of Carcinoma Lung. 10. Barrett's Disease. 11. Risk factors for Endometrial carcinoma. # KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES ## MBBS SECOND YEAR DEGREE SUPPLEMENTARY EXAMINATIONS: SEPTEMBER, 2022 ### PATHOLOGY (NEW REGULATION) #### Paper-II **Time:** 3 Hours **Max Marks:** 100 **Note:** Answer all questions Give Diagrammatic representation wherever necessary. ### Write an essay on the following: **2 x 15 = 30** 1. Classify Emphysema. Discuss the etiopathogenesis and types of Emphysema with a note on gross and microscopy of Emphysema. (3+4+4+4) 2. What is Nephrotic Syndrome? List four causes of Nephrotic Syndrome. Write a note on its pathophysiology. (3+6+6) ### Write a short note on the following: **8 x 5 = 40** 3. Basal Cell Carcinoma, 4. List differences between Ulcerative Colitis and Crohn's Disease. 5. Ewing's Sarcoma. 6. Pleomorphic Adenoma. 7. Graves' disease. 8. Etiopathogenesis of Alcoholic Liver Disease. 9. Hydatidiform Mole. 10. Morphology and complications of Atheroma. ### Write briefly on the following: **10 x 3 = 30** 11. Morphology of Benign Prostatic Hyperplasia. 12. Microscopy of Papillary Carcinoma Thyroid. 13. CSF findings in Tubercular Meningitis. 14. Barett's Oesophagus. 15. Morphology of Osteoclastoma. 16. List the laboratory markers of Acute Myocardial Infarction. 17. Dermoid Cyst of Ovary 18. Morphology of Peptic Ulcer. 19. Endometriosis. 20. Risk factors for Gall Stones. # KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES ## MBBS SECOND YEAR DEGREE SUPPLEMENTARY EXAMINATIONS: SEPTEMBER-2022 ### PATHOLOGY (OLD REGULATION) #### Paper-II **Time:** 2 Hours **Max Marks:** 40 **Note:** Answer all questions Give Diagrammatic representation wherever necessary ### Write Essay on the following question: **1 x 10 = 10** 1. Classify Ovarian Tumours. Describe the pathology of Papillary Serous Cyst Adenocarcinoma of Ovary. (5+5) ### Write Short note on the following: **5 x 4 = 20** 2. Sequelae of an Atheroma. 3. Differentiate between Crohn's Disease and Ulcerative Colitis. 4. Morphology of malignant Melanoma. 5. Etiopathogenesis and Morphology of Alcoholic Liver Disease. 6. Endometriosis- definition, chief locations and histogenesis. ### Write briefly on the following: **5 x 2 = 10** 7. Name four Brain Tumours. 8. Types and Morphology of cardiac Vegetation. 9. Giant Cell tumour- common sites and its radiological, Microscopic picture. 10. Four major etiological factors associated with Hepatocellular Carcinoma. 11. Four complications of Chronic Gastric Ulcer. # KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES ## MBBS SECOND YEAR DEGREE EXAMINATIONS: APRIL/MAY, 2022 ### PATHOLOGY (NEW REGULATION) #### PAPER-II **Time:** 3 Hours **Max Marks:** 100 **Note:** Answer all questions Give Diagrammatic representation wherever necessary. ### Write an essay on the following: **2 x 15 = 30** 1. Discuss the etiopathogenesis of Cholelithiasis. Describe the morphology of different types of Gall Stones. List investigations required. Mention complications of Cholelithiasis. (4+4+4+3) 2. A 60-year-old lady presented with an Ill-defined hard Breast mass that was fixed to the underlying Muscle. - What is your diagnosis and why? Explain. - What are the histologic types of this Lesion - What are the investigations required for diagnosis? - Write a note on Prognostic factors for this Lesion. (3+5+4+3) ### Write a short note on the following: **8 x 5 = 40** 3. Multinodular Goitre. 4. Kidney changes in Hypertension. 5. Meningioma. 6. Nephrotic Syndrome.. 7. Etiopathogenesis of Gastric Carcinoma. 8. Pathogenesis of Bronchial Asthma. 9. Pyogenic Osteomyelitis. 10. Etiopathogenesis of Infective Endocarditis. ### Write briefly on the following: **10 x 3 = 30** 11. Meckels diverticulum. 12. Fibro lamellar variant of Hepatocellular Carcinoma. 13. Gross features of adult Polycystic Kidney. 14. Microscopy of Squamous Cell Carcinoma of Skin. 15. Microscopy of Osteoclastoma of Bone. 16. Gross and microscopy of Osteochondroma. 17. Cervical Intraepithelial Neoplasia (CIN). 18. Microscopy of Schwannoma. 19. Leukoplakia of oral Cavity. 20. Complications of Portal Hypertension. # KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES ## MBBS SECOND YEAR DEGREE EXAMINATIONS: APRIL/MAY, 2022 ### PATHOLOGY (OLD REGULATION) #### Paper -II **Time:** 2 Hours. **Max Marks:** 40 **Note:** Answer all questions. Give Diagrammatic representation wherever necessary. ### Write Essay on the following question: **1 x 10 = 10** 1. A 60 year old man is admitted with history of Chest pain of half hour duration. Severe pain in the precordial area with radiation to the left arm, associated with vomiting, ECG showed ST segment elevation with T Wave Inversion. - What is the most likely Diagnosis? - What are the investigations required? - What are the complications? - What are the predisposing factors of the disease? (2+2+3+3) ### Write a Short note on the following: **5 x 4 = 20** 2. Gastrointestinal Stromal Tumour (GIST). 3. Bowen's Disease. 4. Osteomyelitis. 5. Dense Deposit Disease (Type: 11 MPGN). 6. Phyllodes Tumour. ### Write briefly on the following: **5 x 2 = 10** 7. Complications of Bronchiectasis. 8. Benign Cystic Teratoma. 9. Morphology of Acute Pancreatitis. 10.Paget's disease of Breast. 11.Multi Nodular Goitre # KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCIES ## MBBS SECOND YEAR DEGREE EXAMINATIONS –AUGUST-2021 ### SYSTEMIC PATHOLOGY #### PAPER - II **Time:** 2 Hours. **Max Marks:** 40 **Note:** Answer all questions. Give Diagrammatic representation wherever necessary. 1. A man develops gradual loss of weight, abdominal pain, anorexia and Hematemesis. A mass was detected in Epigastric region. A firm lymph nodal mass in the supraclavicular region and another nodule in the periumbilical region. - What is your probable diagnosis? - Discuss the etiopathogenesis. - Describe in detail Morphology of the lesion (1+4+5=10) ### Write Short note on the following: **5 X 4 = 20** 2. Giant cell tumour of bone-clinical features, Etiopathogenesis, morphology, radiologic findings. 3. Etiopathogenesis and morphology of benign prostatic hyperplasia. 4. Morphology and complications of atheroma. 5. Discuss the stages in the evolution of lobar pneumonia and list the complications. 6. Acute post streptococcal proliferative glomerulonephritis. ### Write Briefly on the following **5 X 2 = 10** 7. What are verocay bodies? 8. List Four complications of cirrhosis. 9. Classification of breast carcinoma. 10. Krukenberg tumor. 11. CSF findings in pyogenic meningitis. # KALOJI NARAYANA RAO UNIVERSITY OF HEALTH SCIENCES ## MBBS SECOND YEAR DEGREE EXAMINATIONS – JANUARY/FEBRUARY-2020 ### PATHOLOGY #### PAPER - II ##### SYSTEMIC PATHOLOGY **Time:** 2 Hours. **Max Marks:** 40 **Note:** Answer all questions. Give Diagrammatic representation wherever necessary. 1. A 40 year old male reported to the hospital with a history of painless enlargement of left testis. Examination revealed a solid mass in his testis. His serum LDH level was raised and AFP level was normal. - What is your differential diagnosis? - Describe the gross and microscopic features of any one type. - Routes of spread of testicular tumors. (2+5+3=10) ### Write Short notes on: **5 x 4 = 20** 2. Ulcerative colitis. 3. Alcoholic liver disease. 4. Dilated cardiomyopathy. 5. Renal stones. 6. Papillary thyroid carcinoma. ### Write Briefly on: **5 x 2 = 10** 7. Complications of asbestosis, 8. CSF findings in pyogenic meningitis. 9. Sites of atherosclerosis. 10. Pancoast tumor. 11. Cardiac vegetation # DR NTR UNIVERSITY OF HEALTH SCIENCES:: VIJAYAWADA - 8 ## MBBS SECOND YEAR DEGREE EXAMINATION - JULY, 2019 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-II **Time:** 2 Hours **Max. Marks: 40** **Note:** Answer all questions Draw neat diagrams wherever necessary 1. A 45 year old woman presented to the surgical OPD with yellowness in eyes and skin, passage of dark coloured urine and pale stools. She complained of right upper abdominal pain on and off, nausea and vomiting. On USG, radio opaque shadows' were seen in Right upper quadrant of abdomen. - What is the most likely diagnosis? - What investigations would be appropriate? - What is the etiopathogenesis of this lesion? - What are the complications of this disease? (1+4+3+2=10) ### WRITE SHORT NOTES ON: **5X4=20** 2. Morphological changes in brain in Alzheimer's disease 3. Etiopathogenesis and morphology of small cell carcinoma lung 4. Morphological features and complications of Ulcerative colitis 5. Etiopathogenesis of Viral hepatitis and its complications 6. Types and morphology of Renal cell carcinoma ### WRITE BRIEFLY ON: **5X2=10** 7. Types of Gall stones 8. Osteosarcoma - its common sites, radiological and microscopic findings 9. Microscopic pattern of follicular adenoma Thyroid 10. Risk factors of atherosclerosis and its complications 11. Causes of prostatic enlargement - write morphology of benign prostatic hyperplasia. # DR NTR UNIVERSITY OF HEALTH SCIENCES :: VIJAYAWADA - 8 ## MBBS SECOND YEAR DEGREE EXAMINATION - FEBRUARY, 2019 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-II **Time:** 2 Hours **Max. Marks: 40** **Note:** Answer all questions Draw neat diagram wherever necessary 1. An 8 year old boy came with history of puffiness of face with decreased urine output. His urine examination revealed numerous RBCs with mild proteinuria. Renal biopsy was performed which showed glomerular hypercellularity with neutrophils. - What is your diagnosis? - Describe the pathogenesis and laboratory findings in this condition. - What are the features on immunofluorescence and electron microscopy? (1+5+4=10) ### WRITE SHORT NOTES ON: **5X4=20** 2. Sequence of serologic markers in acute hepatitis B infection. 3. Light microscopic changes in the evolution of acute myocardial infarction in the first 14 days 4. Pathogenesis of cervical carcinoma 5. Discuss the different types of emphysema 6. Hereditary non-polyposis colorectal cancer ### WRITE BRIEFLY ON: **5X2=10** 7. Four differences between complete and partial mole 8. Enlist four major prognostic factors of carcinoma breast 9. Pathogenesis of Hashimoto's Thyroiditis 10. Microscopic features of basal cell carcinoma 11. Barrett Esophagus # DR NTR UNIVERSITY OF HEALTH SCIENCES :: VIJAYAWADA - 8 ## MBBS SECOND YEAR DEGREE EXAMINATION – JULY, 2018 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-II **Time:** 2 Hours **Max. Marks: 40** **Note:** Answer all questions Draw neat diagrams wherever necessary 1. A 25 year old man is admitted with swelling of the upper end of tibia. X-ray shows a turnover in the metaphyseal area of tibia with evidence of new bone formation. - What is the probable diagnosis? - Give the microscopic picture of the turnover with labeled diagram - Name the organs where it metastasizes - Classify bone tumors (1+2+3+3=10) ### WRITE SHORT NOTES ON: **5X4=20** 2. Classify cirrhosis. Give gross and microscopic picture of alcoholic cirrhosis 3. Give the complications of bronchiectasis 4. What are the sequelae of an atheroma? 5. Differentiate between Crohn's disease and Ulcerative Colitis 6. Give the clinical and biochemical features of Carcinoid syndrome ### WRITE BRIEFLY ON: **5X2=10** 7. Give four complications of gall stones 8. Four Etiopathogenetic factors of urinary bladder cancer 9. Draw a labelled diagram of Seminoma testis and what is the route of spread. 10. Name the thyroid tumors and indicate their route of spread 11. Give four microscopic features of Diabetic Kidney # DR NTR UNIVERSITY OF HEALTH SCIENCES :: VIJAYAWADA - 8 ## MBBS SECOND YEAR DEGREE EXAMINATION – FEBRUARY, 2018 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-II **Time:** 2 Hours **Max. Marks: 40** **Note:** Answer all questions Draw neat diagram wherever necessary 1. A 65 year old man, a chronic smoker, presented with history of weight loss, low grade fever and difficulty in breathing. He gave history of hemoptysis for last month. X-ray chest showed enlarged Right tracheobronchial lymph nodes. Bronchoscopy revealed a fungating growth in the right bronchus. - What is the probable diagnosis - Mention the major types (classification) - Give the spread of the tumour - What is paraneoplastic syndrome? Give features of paraneoplastic syndrome. (1+3+2+4=10) ### WRITE SHORT NOTES ON: **SX4=20** 2. Helicobacter pylori and peptic ulcer 3. Morphology of Myocardial Infarction 4. Give causes of crescent formation. Give gross and microscopic picture of Rapidly progressive glomerulonephritis 5. Post necrotic cirrhosis liver 6. Give the microscopic picture, X-ray appearance and spread of osteogenic sarcoma ### WRITE BRIEFLY ON: **5X2=10** 7. Nodular Sclerosing type of Hodgkin disease 8. Enumerate pathogenic factors of Carcinoma cervix 9. CSF findings in Tuberculous Meningitis 10. Name four prognostic factors of breast cancer 11. What is the pathogenesis of Dissecting aneurysms? # DR NTR UNIVERSITY OF HEALTH SCIENCES :: VIJAYAWADA - 8 ## MBBS.DEGREE EXAMINATON – JULY, 2017 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-11 **Time:** 2 Hours **Max. Marks: 40** **Note:** Answer all questions Draw neat diagrams wherever necessary 1. A 59 year old man is admitted with history of chest pain of half hour duration. Pain was in the precordial area with radiation in the left arm pain was severe in nature and was accompanied by vomiting. ECG showed ST segment elevation with T wave inversion. - What is the most likely diagnosis? - What biochemical investigations are useful in such a case? - What complications can occur? - What are the predisposing factors of this disease? (1+2+3+3=10) ### WRITE SHORT NOTES ON: **5X4=20** 2. Give the gross and microscopic findings in a case of chronic pyelonephritis 3. Pathogenesis of Peptic Ulcer 4. Morphology of acute viral hepatitis and its complications 5. Classify pneumonia. What are the stages of lobar pneumonia? 6. Classify bone tumors. Give X-ray appearance and microscopic picture of giant cell tumor. ### WRITE BRIEFLY ON: **5X2=10** 7. Mention four complications of Bacterial Endocarditis 8. Classify Ovarian tumors 9. Staging of Hodgkin's disease 10. Hashimoto thyroiditis 11. Pathogenesis of Dissecting Aneurysms # DR NTR UNIVERSITY OF HEALTH SCIENCES :: VIJAYAWADA - 520 008 ## MBBS. DEGREE EXAMINATION – FEBRUARY, 2017. ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-II **Time:** 2 Hours **Max. Marks: 10** **Note:** Answer all questions Give Diagrammatic representation wherever necessary 1. An elderly male presented with history of bleeding per rectum, altered bowel habits, loss of appetite, loss of weight and crampy lower quadrant discomfort in the abdomen. Hematological evaluation revealed Iron deficiency anemia. What is your diagnosis? - Discuss the etiopathogenesis of this disease. - Describe the morphology of this lesion. (1+5+4=10) ### WRITE SHORT NOTES ON: **5X4=20** 2. Morphology of liver in Alcoholic Cirrhosis. 3. Morphology of osteoclastoma. 4. Morphology and complications of atherosclerosis. 5. CSF findings in pyogenic meningitis. 6. Morphology of seminoma testis. ### WRITE BRIEFLY ON: **5x2=10** 7. List four causes of chronic glomerulonephritis. 8. Mention four complications of myocardial infarction. . 9. Name any four causes of Carcinoma Lung. 10. Name four Malignant tumors of Thyroid. 11. Name four Malignant tumors of Salivary glands. # DR NTR UNIVERSITY OF HEALTH SCIENCES :: VIJAYAWADA - 8 ## MBBS. DEGREE EXAMINATION – JULY, 2016 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-II **Time:** 2 Hours **Max. Marks: 40** **Note:** Answer all questions Draw, neat diagram wherever necessary 1. A 20 year old female presented with a painless slowly growing freely mobile solitary lump in the lower part of her left breast. On examination, the nipple is normal. The lump is not fixed to the overlying skin. No axillary lymph nodes are palpable. - What is the provisional diagnosis? - Discuss various investigations to confirm your final diagnosis - Describe the gross and microscopic picture of the lesion. (2+4+4=10) ### WRITE SHORT NOTES ON: **5X4=20** 2. Pathogenesis of bronchial asthma 3. Morphology of renal cell carcinoma 4. Etiology of carcinoma cervix 5. Morphology of hepatocellular carcinoma 6. CSF changes in meningitis ### WRITE BRIEFLY ON: **5X2=10** 7. Types of gall stones 8. Give the names of four malignant ovarian tumours 9. Complications of peptic ulcer 10. Microscopic appearance of papillary carcinoma of thyroid 11. Morphology of basal cell carcinoma # DR NTR UNIVERSITY OF HEALTH SCIENCES: VIJAYAWADA - 8 ## MBBS. DEGREE EXAMINATION - JANUARY, 2016 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-II **Time:** 2 Hours **Max. Marks: 40** **Note:** Answer all questions Draw neat diagram wherever necessary A 68-year-old man presented with left sided chest-pain of one hour duration. Päin is: radiating to the left arm. ECG-Bemonstrated. ST. segment elevation with Twave inversion. - What is the probable diagnosis?: - Enumerate the tests you will carry out to diagnose. - What is the gross and microscople picture of the lesion? - What are its complications? (1+3+4+2=10) ### WRITE SHORT NOTES ON: **5X4=20** 2. Gastric carcinoma:-location, types and metastasis 3. Asbestosis 4. Kidney lesions in hypertension 5. Microscopic types of breast cancer 6. Chronic active Kepatitis - etiology, microscopic picture and fate ### WRITE BRIEFLY ON: **5X2=10** 7. Microscopic patterns of follicular adenoma thyroid 8. What are the pathogenic factors of endometrial cancer? 9. Classify.gonadal stromal tumours of ovary and give the hormone secreted by ëäch 10. What are the four precancerous..lesions of large Intestine? 11. Give the gross and morphologic picture of proliferative glomerulonephritis # DR. NTR UNIVERSITY OF HEALTH SCIENCES::AP::VIJAYAWADA-520 008 ## MBBS. DEGREE EXAMINATION – JULY, 2015 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-II **Time:** 2 Hours **Max. Marks: 40** **Note:** Answer all questions Draw neat diagram wherever necessary 1. A 45 year old lady presented with a painless swelling in the left breast for 3 months duration. On examination the swelling was firm, fixed to the overlying skin. Left axillary lymph nodes were enlarged. Fine needle aspiration of the swelling showed loosely cohesive cells with pleomorphic hyperchromatic nuclei and prominent nucleoli. - What is your diagnosis - Describe the etiopathogenesis of this condition - How will you classify this condition? - What are prognostic factors for this condition? (1+6+2+1=10) ### WRITE SHORT NOTES ON: **5X4=20** 2. Atherosclerotic aneurysm 3. Morphology of pleomorphic adenoma of salivary gland 4. Meningioma 5. Morphology of Lobar Pneumonia and complications 6. Benign cystic teratoma of the ovary ### WRITE BRIEFLY ON: **5X2=10** 7. Microscopic appearance of peptic ulcer 8. Name four malignant tumours of the thyroid 9. Gross appearance of osteogenic sarcoma 10. Four differences between Crohn's disease and ulcerative colitis 11. Four causes for cirrhosis of liver # M.B.B.S. DEGREE EXAMINATION – JANUARY, 2015 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-II **Time:** 2 Hours **Max. Marks: 40** **Note:** Answer all questions Draw diagrammatic representation wherever necessary 1) A 55 year old lady present with breathlessness and cough for the past 2 weeks. She gives history of loss of weight and tiredness for past 6 months X-ray chest revealed a massive pleural effusion on the left side. CT scan showed a nodular mass which is peripherally located in the left lung. CT guided biopsy of the mass showed, large cells with pleomorphic nuclei and prominent nucleõli, arranged in a glandular pattern. - What is your diagnosis? (1+5+4=10) - Mention the histological types (sub-classification) of this lesion with illustrations - Describe its etiopathogenesis. ### WRITE SHORT NOTES ON: **5x4=20** 2) Valvular lesions in rheumatic heart disease. 3) Etiopathogenesis of carcinoma stomach 4) Etiopathogenesis of hepatocellular Carcinoma 5) Etiopathogenesis of Chronic Pyelonephritis 6) Morphology of malignant melanoma ### WRITE BRIEFLY ON: **5x2=10** 7) Morphology of uterine leiomyoma 8) Name four brain tumors 9) Three causes of primary hyperparathyroidism and one cause of secondary hyperparathyroidism 10) Microscopic appearance of giant cell tumour of bone 11) Classification of germ celt tumours of testis # M.B.B.S. DEGREE EXAMINATION – JULY / AUGUST, 2014 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY). #### PAPER-11 **Time:** 2 Hours **Max. Marks: 40** **Note:** Answer all questions Draw neat diagram wherever necessary A 54-year old woman noted a 6-month history of progressive vaginal discharge sometimes blood tinged. She was 2 years post menopausal and earlier took oral contraceptives for 10 years. She complains of right back pain and right leg swelling. The per-speculum examination showed an unhealthy cervix with ulceration. - What is the most likely diagnosis? - Write two (2) high risk, two (2) low risk microorganism and two (2) social factors associated with this lesion. - Name the screening tests performed for it. - Describe the preventive measures. (1+6+2+1=10) ### WRITE SHORT NOTES ON: **5X4=20** 2. Morphology of Meningioma. 3. What are the types of pneumonia; write about the morphology of Lobar pneumonia and its complications. 4. Etiopathogenesis and morphology of Carcinoma Prostate. 5. Etiopathogenesis and morphology of Alcoholic liver disease. 6. What are the causes of peptic ulcer, write its morphology and complications? ### WRITE BRIEFLY ON: **5X2=10** 7. Morphology of Post streptococcal Glomerulonephritis. 8. Types of gall stones and their complications. 9. Burkitt's Lymphoma. 10. Type's and morphology of Cardiac vegetations. 11. Giant cell tumor - common sites and its radiological and microscopic picture. # M.B.B.S. DEGREE EXAMINATION – JANUARY, 2014 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-II **Time:** 2 Hours **Max. Marks: 40** **Answer all questions** 1) A male aged 60 years who is a chronic smoker presented with history of slowly increasing severe exertional dyspnoea and weight loss. He is barrel-chested and dyspneic with prolonged expiration, sits forward in a hunched-over position and breaths through.pursed lips - What is the probable diagnosis? (1+4+4+1=10) - Mention the major types (classification) with appropriate diagrams - Discuss the pathogenesis of the lesion - Mention two causes of death in most of these patients ### WRITE SHORT NOTES ON: **5x4=20** 2) Skeletal Ewing's sarcoma - common sites, X-ray appearance and microscopic picture. 3) Endometriosis - Definition, chief locations and histogenesis 4) Cardiac lesions in Acute Rheumatic fever (Acute RHD) 5) Name the types of Renal lesions in Diabetic Nephropathy and describe the histology of glomerular lesions 6) Morphology of Astrocytomas ### WRITE BRIEFLY ON: **5x2=10** 7) Paget's disease of Nipple - Gross and microscopic picture 8) Name three (3) pre-malignant (carcinoma-in-situ) lesions of Penis mention the common infective agent associated with these lesions 9) Morphology of Amoebic colitis 10) Microscopic picture of thyroid in Graves disease 11) Four major etiologic factors associated with Hepatocellular Carcinoma # M.B.B.S. DEGREE EXAMINATION - JULY, 2013 ### PATHOLOGY #### (SYSTEMIC PATHOLOGY) #### PAPER-II **Time:** 2 Hours **Max. Marks: 40** **Answer all questions** 1. A 40 year old female has 16 weeks amenorrhoea and on examination her uterus size was larger and corresponds to 21 weeks size gestation. She complaints bleeding and passing. grape like vesicles per vaginum. Her blood and urine HCG levels are elevated and higher than normal pregnancy. - What is the provisional diagnosis? - Mention the two types of this benign non-invasive lesion and discuss their different pathogenesis - Describe the gross and microscopic picture - Mention the complications (1+3+5+1=10) ### WRITE SHORT NOTES ON: **5x4=20** 2. Lobar Pneumonia 3. Pleomorphic adenoma 4. Wilm's tumor 5. Giant cell tumor - Bone 6. Hashimoto's Thyroiditis ### WRITE BRIEFLY ON: **5x2