Pathology Questions PDF

PATHOLOGY QUESTION What is metaplasia? a) An abnormality of both differentiation and maturation. b) An increase in the number of cells in an organ or tissue c) Increase in the sizes of cells, and hence the size of the organ d) A decrease in the size of a tissue or...

PATHOLOGY QUESTION What is metaplasia? a) An abnormality of both differentiation and maturation. b) An increase in the number of cells in an organ or tissue c) Increase in the sizes of cells, and hence the size of the organ d) A decrease in the size of a tissue or organ e) A reversible change in which one mature cell type is replaced by another mature cell type What is congestion? a) Formation of a solid mass from the constituents of blood within the heart or vascular system in a living organism b) Impaired venous drainage c) The accumulation of abnormal amounts of fluid in the intercellular tissue spaces or body cavities d) Augmented supply of blood to an organ e) The occlusion or obstruction of a vessel by an abnormal mass (solid, liquid, or gaseous) transported from a different site by the circulation All of the following is morphological pattern of irreversibl cell injury; a) Pyknosis b) Karyorrhexis c) Karyolysis d) Lysosome breakdown What is the reason of atropy a) Poor populations b) Fixation c) Severe protein-calorie malnutrition d) Hypoxia e) All of them Please write feature of apoptosis a) Programmed single cell suicide b) There is never any rupture of the cell membrane c) Acute inflammatory cells do not play role d) Apoptotic cells may be phagocytized by their neighbors e) Apoptotic bodies occur All of the following is morphological pattern of reversibl cell injury; a) Fatty change b) Loss of microvilli c) Clumping of nuclear chromatine d) ER swelling e) Cellular swelling What is the thrombosis? a) Tissue death caused by blockage of total blood flow b) The occlusion or obstruction of a vessel by an abnormal mass (solid, liquid, or gaseous) transported from a different site by the circulation c) A clinical state characterized by a generalized decrease in perfusion of tissues (circulatory collapse) associated with decrease in effective cardiac output. d) The accumulation of abnormal amounts of fluid in the intercellular tissue spaces or body cavities e) Augmented supply of blood to an organ Please writre type of necrosis a) Caseous b) Coagulation c) Fibrinoid d) Fat e) …….. f) …….. Which one is not a feature of chronic inflammation? a) Fibrosis b) Tissue destruction c) Mononuclear cell infiltration d) Angiogenesis e) Edema Which one of the following pigments is responsible for jaundice? a) melanin b) hemosiderin c) lipofuscin d) bilirubin e) amyloid Which one of the followings is a complication of wound healing? a) Keloid formation b) Granulation tissue formation c) Reperation d) Regeneration e) Inflammation Subcutaneous collection of erythrocytes that are larger than 1cm in diameter are called: Hematoma Petechia Purpura Urticaria Ecchymosis Hemodynamic disorders are characterized by…… a) Disturbed perfusion that results in organ and cellular injury b) Disturbed inflammatory reaction c) Disturbed self tolerance mechanism d) Disturbed reparation mechanism e) Disturbed immunological mechanism Which one of the listed statements best describes the process called chemotaxis? a) Abnormal fusion of phagosomes to primary lysosomes b) Attachment of chemicals to extracellular material to increase phagocytosis c) Dilation of blood vessels by chemotherapeutic drugs d) Movement of cells toward a certain site or source e) Transmigration of cells from blood vessels into tissue. Which of the following one is a malignant tumor ? a) Melanoma b) Leiomyoma c) Chondroma d) Osteoma e) Adenoma Which one of the following is a stable cell? a) Bone marrow b) Heart muscle c) Oral cavity d) Vascular endothelium e) Skin Which one of the histochemical techniques can be performed to differentiate iron from other pigment depositions? a) Mucicarmine b) Congo red c) Periodic-acid Schiff d) Prussian Blue e) Alcian Blue Which of the following lesion is not tumor? a) Adenoma b) Papilloma c) Lymphoma d) Hamarthoma e) Osteoma Which is the most susceptible type of cell to hypoxic injury? a) neurons b) striated muscle c) epidermis d) hepatocyte-liver cell e) renal tubular cell Which one is a precancerous lesion? a) Aplasia b) Hypoplasia c) Hypertrophy d) Dysplasia e) Hyperplasia What is the main fixative solution in pathology? a) Formaline b) Alcohol c) Saline d) Water e) Acid Multinucleated giant cells originate from: a) Lymphoyte b) Fibroblast c) Endothelial cell d) Macrophage e) Eosinophils 26- What is HEMORRHAGE? a) Formation of a solid mass from the constituents of blood within the heart or vascular system in a living organism b) Presence of blood in interstitial tissue outside the blood vessels and heart c) Augmented supply of blood to an organ d) The accumulation of abnormal amounts of fluid in the intercellular tissue spaces or body cavities e) The occlusion or obstruction of a vessel by an abnormal mass (solid, liquid, or gaseous) transported from a different site by the circulation Which one is a feature of acute inflammation? a) Fibrosis b) Tissue destruction c) Edema d) Mononuclear cell infiltration e) Angiogenesis During the tissue processing, which of the following chemical solution dissolve the accumulation of lipid? a) Formaline b) Alcohol c) Eosin d. Water e. Paraffin Which one is the most common cause of cell injury and cell death? a) Viral agents b) Hypoxia c) Bacterial agents d) Chemical injury e) Radiation Which of the following is the most common malignant tumor in women? a) Lung b) Breast c) Colon d) Pancreas e) Ovary 38. What is the hallmark of reversible injury? a) Cellular swelling b) Cell necrosis c) Apopytosis d) Lysis e) Nuclear damage Which of the following biopsy technique is the sampling method used in patients diagnosed with cancer (malignancy)? a) Endoscopic biopsy b) Incisional biopsy c) Excisional biopsy d) Radical surgery e) Bone marrow sampling