Pharmacotherapeutics Week 1 Notes PDF

Summary

These notes cover pharmacotherapeutics, focusing on the different types of drugs and their mechanisms of action, as well as the approval process.

Full Transcript

Pharmacotherapeutics Week 1 4 youdon'thavetomemorizeslidesthathaveFYI on them Pharmacology medicineand logos tostudy Is intestate emember Symptomstell us ifthatthere ifeng...

Pharmacotherapeutics Week 1 4 youdon'thavetomemorizeslidesthathaveFYI on them Pharmacology medicineand logos tostudy Is intestate emember Symptomstell us ifthatthere ifeng.IE sg is issue isdrug anunderlying sowewanttotreattheunderlyingissue insteadofjustthesymptomsifpossibleex ifsomeonehas afeverweshouldgetrid ofthepathogen ausingthefeverandnotonlyfocusonthefever Beforethe 20ᵗʰcentury1900s naturesourcedremedies were used andwouldworkbecause oftheactiveingredientsinthem Sincethe 20ᵗʰcentury 1900s activeingredientsinnaturesourcedremedies arebeingartificially replicatedex theactiveingredientinmoldsisartificiallyreplicatedandthendistributed as penicillin an antibiotic basicallyusingdrugstoachieveatherapeuticpurpose harmacotherapeutics Pharmacotherapeutics is the use ofmedicinesdrugstotreat manageoralleviatepatients conditions Nursesperformpharmacotherapeuticswhentheyadministerdrugsunderstandhowdrugsmove throughthebodymonitorhowthebodyrespondsto thedrugandmanageinteractionsbetween emelmiler There are somedrugsthat can safelyinteractwith oneanotherwhileotherscan be eryharmfulwhencombined The3 maincategoriesofpharmacotherapeutics are 1 Drugmedication a chemicalagentthat issyntheticallyproducedex ibuprofen 2 Biologic substancesthat are naturallymadeinhumansanimals ormicroorganisms ex antibodiesredbloodcellsandhormoneslikeinsulin If it hastobeinjectedandcannotbetakenorally viathemouth it is mostlikely abiologic 3 Natural healthproducts comefromnaturalsourcesex vitaminsmineralsanddietarysupplements likeproteinpowder Naturalhealthproductsare hardertoregulatethandrugsandbiologics ex echinaceais an herbthatboostsimmunitybutsincenotallechinaceashavethe samechemicalmakeupit'shardto getthe sameeffectiveness Approvalprocess of pharmacotherapeutics ememberTheapprovalprocessfordrugsare morestringent esearch Preclinicaltrialsofthedrugon non humans Bhagenta phrasesonupto100 faintest healthyvolunteer Phase2 ofclinical trialson upto300sickvolunteers Phase3 ofclinicaltrialsonupto3000volunteers NewDrugSubmission NDStoHealthCanada Noticeofcomplianceanddrugidentificationnumber DIN assignedto thedrug Drugmonitoredincaseanythingbad happens Eachprovince decidesiftheywantto havethedruganddistributeit or not ex somedrugsinAlbertamightnotbeavailableinQuebec drugsCANbeusedinspecialcircumstances via thespecialaccessprogram Teppei itftp.pgued Asubstancethat is saidtohavean effectwhichmightleadto an actualeffect ex If Idrinkwarm day I stayhealthy andthen itactuallyends upworkingplaceboeffect waterevery TheDeclaration of Helsinkistatesthat amedicationinclinicaltrialshouldNOTbecomparedto a placebounlessthereis nobettertreatmentat that time DrugNames RememberEverydrughas adrugname The 3typesofdrugnames are 1 Chemical thedrugname is basedoff how thedrugis chemicallymadeup ex potassium chloride 2 Generic thedrugname that is the same all over the world and is notsassociatedwithanything ex ibuprofen Cheaper 3 Brand trade namedbythecompanywhomade it and isoftenthe1stdrugonthemarket There are manybrand names per onegenericdrugex AdvilMotrilandAleveare brandnames Then Pineradigitstheitariet that theyalsohave ageneric name Moreexpensive n pÉÉtyPpefriglisonedrugchosenfrom adrugclassandused as theprecedentororiginal DrugClasses are organizedintodrugclasses Im Eggs pesofdrugclasses are Therapeutic thename ofthedrugindicatesthetreatmenttherapyof adisease ordisorder blood pressure ex antihypertensivedrugslowerhighBp 2 Pharmacological thename ofthedrugindicateshowitworksmechanismofactionandis morerecepto specificexcalciumchannelblockersblockcalciumchannels DrugSchedules The 4 mainschedulesofdrugs are 1 Schedule 1 thesedrugs canonlybe used if prescribedby a nurse NP ordoctor Strictlymeasured sincetheycaneasilybe misused ex medicalcannibisprescription 2 Schedule 2 thesedrugsdonotneed to beprescribedandonly a pharmacist can givethedrugexTylenolthat has a lot of some codeine in it or strongdosesof iron 3 Schedule 3 thesedrugs areonlyfound in a pharmacyorpharmacy area and are known as over the counter OTCdrugsex non medicated cannibis is aschedule3 drugsince it isonlystored insupervisedstores 4 Unscheduled thesedrugscan besold in anystorewithoutsupervisionneeded

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