Pharmaceutics 2nd Year Past Paper PDF

## PHARMACEUTICS - INDUSTRIAL AND QUALITY CONTROL 1. Which of the following can be the most suitable binder for the manufacturing of Ciprofloxacin tablets by way of wet granulation? - Magnesium stearate - Avicel - Silicon dioxide - Starch 2. Which of the following can be used as a...

## PHARMACEUTICS - INDUSTRIAL AND QUALITY CONTROL 1. Which of the following can be the most suitable binder for the manufacturing of Ciprofloxacin tablets by way of wet granulation? - Magnesium stearate - Avicel - Silicon dioxide - Starch 2. Which of the following can be used as a disintegrant during manufacturing of Paracetamol tablets by way of direct compression? - Titanium dioxide - Microcrystalline cellulose - Sodium acetate - Starch 3. Which of the following material increases the flow of powder from hopper to the die of the tablet compression machine? - Magnesium stearate - Talcum - Titanium dioxide - Silicon dioxide 4. What is the role of wet screening in wet granulation of tablets? - Lubrication of tablets - Disruption of lumps and wet mass into particles - Converting large dry particles into smaller dry particles - Proper mixing of granules 5. Which of the following equipment is used for slugging? - Z.P-19 - Roller compactor - Dry granulator - Wet granulator 6. Which type of APIs are unsuitable for wet granulation method? - Heat labile - Heat sensitive - Hygroscopic - Synthetic 7. Which of the following is the disadvantage of plastic material? - Flexibility - Light in weight - Durability - Stress cracking 8. Which of the following is a substance added to the primary solvent in small amount to increase the solubility of a poorly soluble compound? - Solvent - Suspending agent - Co solvent - Emulsifying agent 9. Which of the following is used as an antioxidant in pharmaceutical preparations? - Methyl paraben - Sodium propyl paraben - Sodium acetate - Vitamin C 10. During the preparation of an extemporaneous preparation, you have been given some tablets to crush and mix them with a syrup. Which of the following ingredient can be added to reduce the sedimentation and increase the suspensibility of powder? - Carboxymethyl cellulose sodium - Sodium ascorbate - Sodium metabisulfite - Citric acid 11. Which is the first step during the preparation of emulsion by wet gum method? - One part of water and one part of acacia mixture is to be triturated. - Two parts of water and one part of acacia mixture is to be triturated. - One part of water and two parts of acacia mixture is to be triturated. - The oil is mixed in acacia with mortar and pestle. 12. Which is the first step during the preparation of emulsion by dry gum method? - One part of water and one part of acacia mixture is to be triturated. - Two parts of water and one part of acacia mixture is to be triturated. - One part of water and two parts of acacia mixture is to be triturated. - The oil is mixed in acacia with mortar and pestle. 13. What should be the ratio of oil, water and acacia for the preparation of emulsion by bottle method? - 1:1:2 - 2:1:1 - 1:2:1 - 1:2:3 14. Which of the following is an opaque, viscous, relatively soft, consistently spreadable, semisolid emulsion dosage forms that often comprise more than 20% water and volatiles and normally less than 50% hydrocarbons, waxes, or polyols as the vehicle for the drug substance? - Ointment - Cream - Paste - Gel 15. Which is a written document or instruction detailing all steps and activities of a process or procedure? - Work instructions - Standard operating procedure - GMP guidelines - WHO instructions 16. Which of the following is the mirror that shows the actual image of any pharmaceutical company? - SOPs - Work Instructions - Quality forms - Documentation 17. Who is responsible for maintaining the quality of a product? - Quality Assurance - Quality control - Quality audit - Every employee 18. Which of all the metal containers is the cheapest? - Aluminum - Steel - Tin - Lead 19. What is the biggest limitation associated with glass containers? - Does not deteriorate - Heavy - Protection from UV light - Fragile 20. Which of the following is the main type of rubber used in parental containers sealing and packaging? - Butyl rubber - Nitrile rubber - Synthetic - Natural rubber 21. How is the sedimentation of particles in a suspension maintained? - By increasing the particle size of the active ingredient. - By increasing the viscosity of the medium. - By preventing the exposure of the drug to the solvent. - By decreasing the particle size of the active ingredient. 22. If a parenteral product contains light sensitive ingredients, which type of glass can be used as primary packaging material? - Amber glass - Transparent glass - Type I glass - Type II glass 23. How many types of glass containers are used to pack pharmaceutical products? - 2 - 4 - 6 - 8 24. Which of the following is an example of tonicity modifier in sterile preparation? - Phenol - Lactic acid - Sodium hydroxide - Sodium chloride 25. What are the adverse effects of permeation of gases, vapors or liquid through plastic containers on drug? - It stabilizes the shelf life of the drug. - It changes the color of the plastic container. - It can initiate hydrolysis and oxidation reactions. - It can cause leakage in the container. 26. Which of the following classes of chemical agents are used to maintain the pH of the injections? - Solvents - Antioxidants - Buffers - Preservatives 27. Which of the following is the preferred pH in the preparation of ophthalmic products that avoids discomfort upon instillation into the eyes? - 4.7 - 6.8 - 7.4 - 8.0 28. What is the advantage of plastic containers? - Heavy in weight - Permeability of moisture - Permeability of gases - Non breakable 29. Which of the following options best explains NP with reference to the parenteral products? - Non pyrogenic - Non plastic - Non protectant - Non parental 30. Which of the following rays are most commonly used in the process of radiation sterilization? - X-rays - beta rays - Gamma rays - UV rays ## PHARMACEUTICS - HOSPITAL AND COMMUNITY PHARMACY 31. All of the following are health accessories **EXCEPT** - Blanket - Wheel chair - Hospital bed - Cable 32. All of the following are health accessories **EXCEPT** - Thermometer - Sphygmomanometer - Viscometer - Towel and washcloths 33. All of the following are operation theatre supplies **EXCEPT** - Operating table - Protective cap - Electronic blood pressure measuring machine - Electronic treadmill 34. WHO initiated EPI for children vaccination, where EPI stands for: - Untended programs on immunization. - Expanded program on immunization. - Expanded program initiative. - European payment initiative. 35. Which of the following is a communicable disease? - Stroke - Heart attack - Hepatitis - Asthma 36. Which of the following is a communicable disease? - Congenital heart failure - Pulmonary hypertension - Hypertension - Chicken pox 37. Which of the following is a non-communicable disease? - AIDS - Ebola - COVID - Cancer 38. At what age is BCG administered? - At birth - 6 week - 10 week - 2 year 39. Which route of administration is used for OPV? - IM - IV - SC - PO 40. What is the effectiveness of birth control pills in family planning? - 80% - 85% - 90% - 95% 41. What is the effectiveness of birth control injections in family planning? - 80% - 85% - 90% - 95% 42. What is the effectiveness of male condom in family planning? - 80% - 86% - 90% - 95% 43. STI stands for? - Sexually transmitted indication - Sexually transmitted infection - Sexually transferred infection - Safely transmitted infection 44. Which of the following is a hospital equipped and staffed to provide care for patients suffering from major injuries such as falls, motor vehicle collisions, or gunshot wounds? - District hospital - Clinic - Surgical hospital - Trauma center 45. If the dose is administered less or more than the ordered dose, which type of error will it be considered? - Wrong site error - Wrong dosage form error - Wrong dose error - Wrong time error 46. Which of the following is the study & practice to improve the overall health of populations rather than individual? - CDC - EPI - Public health - Immunization 47. What is meant by pharmacotherapy? - Medical treatment by radiations - Medical treatment by vaccines - Medical treatment by isotopes - Medical treatment by drugs 48. It was clearly mentioned on the label of Amoxycillin suspension that reconstitute the powder with cool boiled water but the patient reconstitutes it with milk. What type of medication error is it? - Incorrect preparation - Incorrect rate - Incorrect dosage form - Incorrect duration 49. Physician prescribed Cetrizine tablet OD but the patient takes it BD mistakenly. Which type of medication error is it? - Incorrect preparation - Incorrect rate - Incorrect dosage form - Incorrect duration 50. All of the systems are used for drug distribution in a hospital EXCEPT: - Individual Prescription Order System - Complete Floor Stock System - The multi dose method - Combination of (i) and (ii) 51. The process of ensuring the right amount of medicine is available in the hospital is known by which of the following? - Inventory control - Storage - Record keeping - Order system