Metal Biomaterials PDF

Maria Xuereb B.Ch.D MSc  A biomaterial is “a material intended to interface with biological systems to evaluate, treat, augment or replace any tissue, organ or function of the body” A biomaterial is any matter, surface, or construct that interacts with living systems. It should support natura...

Maria Xuereb B.Ch.D MSc  A biomaterial is “a material intended to interface with biological systems to evaluate, treat, augment or replace any tissue, organ or function of the body” A biomaterial is any matter, surface, or construct that interacts with living systems. It should support natural conditions including pH, temperature, corrosion etc.  Intern layout (placed inside the body) and external layout biomaterials (exterior of the body).  Materials of synthetic as well as of natural origin in contact with tissue, blood and biological fluids, and intended for the use for prosthetic, diagnostic, therapeutic, and storage applications without adversely affecting the living organism and its components (Bruck 1980)  Physical requirements Hard material Flexible material  Chemical requirements Relatively inert Non-toxic Serve as a long-term replacement  Bio-functionality Playing a specific function in physical and mechanical terms  Biocompatibility The ability of a material to perform with an appropriate host response in a specific situation (absence of carcinogenity, absence of immunogenicity, absence of teratogenicity, non-toxic).  Thrombosis  Haemolysis  Inflammation  Infection  Carcinogenesis  Hypersensitivity  Rejection  Systemic effects