Summary

This document provides information on various medications and treatments for different conditions. It includes details on CNS stimulants, non-stimulants, substance use disorder medications, and withdrawal symptoms. The document also covers opioid withdrawal medications and nicotine withdrawal.

Full Transcript

MEDS UNIT THREE CNS Stimulants - Risk- abuse, misuse, growth suppression, mania, psychosis, hallucinations, tics, decreased neutrophils Methylphenidate- - Short acting, immediate release- take 2-3 times per day - Intermediate, long acting, transdermal Dextroamphetam...

MEDS UNIT THREE CNS Stimulants - Risk- abuse, misuse, growth suppression, mania, psychosis, hallucinations, tics, decreased neutrophils Methylphenidate- - Short acting, immediate release- take 2-3 times per day - Intermediate, long acting, transdermal Dextroamphetamine, Dextroamphetamine-Amphetamine- Adderall Non-Stimulant- Atomoxetine- SNRI -second line- used if stimulants give too much of a SE/intolerance -SE- HTN, tachycardia, insomnia, HA, GI sx, erectile dysfunction Antihypertensives (alpha agonists) Clonidine- oral/transdermal SE- hypotension, drowsiness, rebound hypertension as withdrawal, dermatitis Guanfacine SE- hypotension, drowsiness, rebound HTN, Uncommon SE- cardiac AV block, SA block, palpitations Substance use disorder meds: Alc withdrawal: DO NOT TAKE Bupropion- BC OF SEIZURE RISK- W ALC WITHDRAW Naltrexone- PO, IM med, opioid antagonist SE- usually well tolerated, GI effects, effect on LFT but should trend down -REDUCES THE CRAVING FOR ALCOHOL, DECREASES THE EFFECT Disulfiram -will make the person feel sick if they drink alc -the rxn will prevent person from drinking alc while on this med Acamprosate- dosed 3x per day, less common - Reduces sx of withdrawal - Alc Withdrawal- TREATED W BENZOS - Chlordiazepoxide, Lorazepam, Diazepam Also possible use of anticonvulsant- Phenobarbital (BENZOS withdrawal- treated w Benzos) Opioid withdrawal meds: Naloxone- poor oral availability, opioid antagonist - Used in opioid overdose Methadone- used for withdrawal- full opioid agonist -stops withdrawal, long half life, needs to be started low and increasing slow -also used for chronic pain- PO -for withdrawal- LIQUID form -SE- resp depression, constipation, sedation, hyperhidrosis -DO NOT USE IF QTC PROLONGATION IS PRESENT - has NO ceiling effect Buprenorphine- used in medication-assisted treatment (MAT) to help people reduce or quit their use of heroin or other opiates, such as pain relievers like morphine. Withdrawal from Nicotine: Nicotine gum, lozenge, patch - NOT LIKE REGULAR CHEWING GUM -bite down slowly until tingling is felt on mouth, then place gum between cheek and gums, repeat the placing for 30 mins until tingling stops

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