Plasma Proteins Quiz PDF

Plasma Proteins Quiz Part One: Simple MCQs 1. Where are most plasma proteins synthesized? ○ (A) Pancreas ○ (B) Liver ○ (C) Kidneys ○ (D) Spleen 2. Which plasma protein is responsible for maintaining the majority of plasma osmotic pressure? ○ (A) Fibrinogen ○ (B) Albumin ○ (C) Glob...

Plasma Proteins Quiz Part One: Simple MCQs 1. Where are most plasma proteins synthesized? ○ (A) Pancreas ○ (B) Liver ○ (C) Kidneys ○ (D) Spleen 2. Which plasma protein is responsible for maintaining the majority of plasma osmotic pressure? ○ (A) Fibrinogen ○ (B) Albumin ○ (C) Globulins ○ (D) Transferrin 3. What is the normal range for total plasma protein concentration? ○ (A) 1-3 g/dL ○ (B) 3.5-5.5 g/dL ○ (C) 6-8 g/dL ○ (D) 10-12 g/dL 4. Which type of globulin is responsible for the transport of iron in the blood? ○ (A) α1-globulins ○ (B) α2-globulins ○ (C) β-globulins ○ (D) γ-globulins 5. Which protein is the major serine protease inhibitor in human plasma? ○ (A) Haptoglobin ○ (B) α1-antitrypsin ○ (C) Ceruloplasmin ○ (D) Transferrin 6. What is the function of haptoglobin? ○ (A) Binds free hemoglobin ○ (B) Transports iron ○ (C) Acts as an antibody ○ (D) Maintains plasma osmotic pressure 7. Which protein is a marker for hepatocellular carcinoma? ○ (A) α1-antitrypsin ○ (B) α1-fetoprotein ○ (C) Ceruloplasmin ○ (D) C-reactive protein 8. Which of the following is a negative acute-phase protein? ○ (A) C-reactive protein ○ (B) Fibrinogen ○ (C) Albumin ○ (D) Haptoglobin 9. What is the main function of fibrinogen? ○ (A) Transport of oxygen  ○ (B) Blood clot formation ○ (C) Immune defense ○ (D) Osmotic regulation 10. Which condition is associated with decreased levels of ceruloplasmin? ○ (A) Iron deficiency anemia ○ (B) Wilson's disease ○ (C) Menkes disease ○ (D) Acute inflammation Answer Guide 1. B 2. B 3. C 4. C 5. B 6. A 7. B 8. C 9. B 10. C Part Two: Complex MCQs 11. A patient presents with edema and a total protein level of 4 g/dL. Which plasma protein is most likely to be deficient? (A) Fibrinogen (B) Albumin (C) Haptoglobin (D) Transferrin 12. Why does a newborn with elevated bilirubin levels should not be given drugs like aspirin or sulfonamides? (A) These drugs increase bilirubin production in the liver (B) These drugs compete with bilirubin for binding to albumin, leading to increased free bilirubin (C) These drugs inhibit the excretion of bilirubin  (D) These drugs have no effect on bilirubin levels 13. A patient is diagnosed with emphysema. How might a deficiency in α1-antitrypsin contribute to this condition? (A) α1-antitrypsin deficiency leads to increased collagen production in the lungs (B) α1-antitrypsin deficiency results in decreased oxygen transport (C) α1-antitrypsin deficiency allows elastase to damage lung tissue unchecked (D) α1-antitrypsin deficiency causes an autoimmune reaction in the lungs 14. Why is measuring haptoglobin levels useful in diagnosing hemolytic anemia? (A) Haptoglobin levels increase during hemolysis (B) Haptoglobin levels decrease during hemolysis due to binding with free hemoglobin (C) Haptoglobin is a marker for red blood cell production (D) Haptoglobin has no relation to hemolytic anemia 15. What is the significance of the albumin/globulin ratio (A/G ratio) in liver disease? (A) A decreased A/G ratio indicates impaired liver function (B) An increased A/G ratio indicates impaired liver function (C) The A/G ratio is not affected in liver disease (D) The A/G ratio is only relevant in kidney disease 16. Which of the following is an example of a negative acute-phase protein? (A) C-reactive protein (CRP) (B) Fibrinogen (C) Transferrin (D) Haptoglobin 17. Elevated levels of α1-fetoprotein in a pregnant woman's blood could indicate: (A) A normal pregnancy (B) Fetal abnormalities or certain tumors (C) Low risk of Down syndrome (D) Premature birth 18. Ceruloplasmin deficiency can lead to: (A) Increased iron absorption (B) Copper deficiency (C) Copper accumulation and tissue damage (D) Enhanced melanin synthesis 19. Which structural feature of albumin contributes most to its role in maintaining plasma osmotic pressure? (A) Its high molecular weight (B) Its low molecular weight and high concentration (C) Its ability to bind to various molecules (D) Its role in blood clotting 20. Why does the level of transferrin increase in iron deficiency anemia? (A) To decrease iron absorption (B) To increase iron transport and capture (C) To promote red blood cell destruction (D) To inhibit iron utilization 21. What is the main difference between plasma and serum in terms of protein composition? (A) Plasma contains albumin, while serum does not  (B) Serum contains immunoglobulins, while plasma does not (C) Plasma contains fibrinogen, while serum does not (D) There is no difference in protein composition between plasma and serum 22. C-reactive protein (CRP) measurement is clinically significant because: (A) It indicates the presence and severity of inflammation (B) It is a marker for iron deficiency (C) It assesses liver function (D) It measures blood clotting ability 23. The primary function of immunoglobulins is to: (A) Transport oxygen (B) Maintain osmotic pressure (C) Provide immune defense against antigens (D) Regulate blood clotting 24. Which of the following is NOT a cause of hypoproteinemia? (A) Liver cirrhosis (B) Nephrotic syndrome (C) Burns (D) High protein diet 25. The high negative charge at the amino-terminal end of fibrinogen: (A) Promotes its aggregation in plasma (B) Prevents its aggregation and maintains its solubility (C) Is essential for binding to hemoglobin (D) Facilitates its transport of iron