GYNE 1.06 Abnormal Uterine Bleeding PDF

Summary

This document provides an overview of abnormal uterine bleeding, including the physiology of normal menstruation, pathology, diagnosis, practice updates, and paradigms of practice. It features key characteristics of normal menstruation and definitions of terms. The document appears to be lecture notes or study material, not a past paper.

Full Transcript

GYNECOLOGY II Abnormal Uterine Bleeding: Paradigms of Practice​​ ​ ​ ​ Block 1 Ma. Asuncion A. Fernandez, MD, FPOGS, FPSRM, FPSGE | January 20, 2025​ ​ ​ ​...

GYNECOLOGY II Abnormal Uterine Bleeding: Paradigms of Practice​​ ​ ​ ​ Block 1 Ma. Asuncion A. Fernandez, MD, FPOGS, FPSRM, FPSGE | January 20, 2025​ ​ ​ ​ GYNE 1.06 OVERVIEW I.​ PHYSIOLOGY OF NORMAL MENSTRUATION I.​ Physiology II.​ Pathology A.​ Description A.​ Description A.​ Definition of Terms ​ B.​ Demography (POGS) C.​ Documentation B.​ Differentials ​ D.​ Defining events (PALM COIEN) III.​ Proper Diagnosis IV.​ Practice and Management Updates V.​ Paradigms of Practice ⭐ Emphasized / repeatedly discussed by the lecturer ABBREVIATIONS AUB Abnormal Uterine Bleeding CEE Conjugated Equine Estrogen COC Combined Oral Contraceptive Pills EMB Endometrial Biopsy ES Endometrial Stripe The International Federation of Gynecology FIGO and Obstetrics HMB Heavy Menstrual Bleeding ID/A Iron Deficiency Anemia MBL Mean Blood Loss MMP Matrix Metalloproteinases MUSA Morphological Uterus Sonographic Assessment National Collaborating Centre for Women’s​ Figure 2. Normal HPO axis. NCCWCH and Children’s Health The hypothalamus releases GnRH, which acts on the pituitary gland to NICE National Institute for Health and Clinical Excellence secrete FSH and LH, which in turn stimulates follicular development. These follicles will release hormones such as estradiol, progesterone, inhibins, PAI Plasminogen Activator Inhibitor activins and follistatins. Progesterone and estradiol at different POGS Philippine Obstetrical and Gynecological Society concentrations or ratios can either have positive or negative feedback on the TCRE Transcervical Resection of the Endometrium hypothalamus-pituitary axis in regulation of the secretion of FSH and LH. TVS Transvaginal Ultrasound USG Ultrasonography ​ Control requirements (basic principles of menarche) 1.​ Outflow tract should be intact 2.​ Of course, endometrial shedding! *TH Note: This trans has similar content with Trans 2026 as the same 3.​ Ovarian function regulation should be normal recorded lecture was used by Doc. Please be guided accordingly. ​ Characteristics ○​ Can vary greatly among women INTRODUCTION ○​ Can change dramatically from cycle to cycle Table 1. Key characteristics of normal menstruation. Mean Interval 28 days ± 7 days (24-35 days) Duration 4-7 days (Average of 6 days) Amount 60% conclusions were made: years of age 28 days = 15% ○​ 1 in 20 women consults a general practitioner each year for heavy menstrual bleeding (HMB) ○​ 4th most common condition that requires referral to a gynecologist for investigation and treatment ○​ Hysterectomy used to be the treatment for HMB for women 20 days extraction methods. Prolonged >8 ​ Actual measurement of menstrual blood loss is Duration of flow inconvenient, time-consuming, and expensive. As such, Normal 4.5-8 (days) other methods to assess heavy bleeding are necessary. Shortened 80 Volume of monthly Women with NORMAL QUESTION blood loss Normal 5-80 menstrual periods tend to: (mL) How often do you change Light

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