Cosmetics Technology Tutorial 6 PDF

Cosmetics Technology [ELCT 1021] Tutorial 6 Course Instructor: Dr. Shahir Aziz ([email protected]) Teaching Assistants: Raghda Hassan ([email protected]) Shehabeldeen Ashraf ([email protected]) 1 Tutorial Outline Skin Dermis’ Cells &...

Cosmetics Technology [ELCT 1021] Tutorial 6 Course Instructor: Dr. Shahir Aziz ([email protected]) Teaching Assistants: Raghda Hassan ([email protected]) Shehabeldeen Ashraf ([email protected]) 1 Tutorial Outline Skin Dermis’ Cells & Structure Skin Dermis’ Cells & Structure – Ageing Factors that affect Ageing Extracted Bioactive ingredients Hyaluronic Acid Collagen and Gelatin Chitosan Ceramide 2 Skin Dermis’ Cells & Structure - Fibroblasts are the most abundant cells in the dermis. They synthesize the complex extracellular matrix (ECM) containing; Collagen, Elastin and Glycosaminoglycans (GAGs). 3 Skin Dermis’ Cells & Structure – Ageing https://www.youtube.com/watch?v=gQbisqok0EU 4 Skin Dermis’ Cells & Structure – Ageing i. Collagen : It is protein molecules made up of amino acids. It provides structural support to the extracellular space of connective tissues. Collagen can be further divided into several groups depending on the type of structures they form. There are 28 various types of collagen that have been discovered, but by far, the most common are types I through IV, with type I comprising over 90% of the collagen in the human body. 5 Skin Dermis’ Cells & Structure – Ageing ii. Elastin : It is one of the most abundant proteins in your body. It’s a stretchy protein that resembles a rubber band — it can stretch out (extend) and shrink back (recoil). It’s a major component of tissues in your body that require stretchiness, like your lungs, bladder, large blood vessels and some ligaments. Smaller amounts exist in your skin and ear cartilage. 6  Skin Dermis’ Cells & Structure – Ageing iii. Glycosaminoglycans (GAGs): GAGs, also known as mucopolysaccharides, are negatively-charged polysaccharide compounds. a family of naturally-occurring carbohydrates that assist in supporting and maintaining collagen and elastin in the skin. They are mainly composed of hyaluronic acid (HA), dermatan sulphate (DS) and chondroitin sulphate (CS). 7 Factors that affect Ageing 8 Extracted Bioactive ingredients Hyaluronic Acid Hyaluronic acid — also known as hyaluronan or hyaluronate — is a gooey, slippery polysaccharides that your body produces naturally. Scientists have found hyaluronic acid throughout the body, especially in eyes, joints and skin. HA is formed repeating units comprised of N-acetyl-d-glucosamine (GalNAc) and d- glucuronic acid (GlcA). It plays a significant role in skin integrity and moisture lock, which is the reason for its anti-ageing effect. 9 Extracted Bioactive ingredients Hyaluronic Acid HA is classified by its MW as: High MW (>1000K Daltons); Low MW, (10K-1000K Daltons); Oligo (