Enzyme Part 4 PDF by Dr. Mohamed Khomsi Aug/2024
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Uploaded by RealisticIndianArt
2024
Dr. Mohamed Khomsi
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Summary
This document is part 4 of a document on Enzyme, from Dr. Mohamed Khomsi, and it appears to be lecture notes formatted as a document with topics such as enzyme function, active sites and factors that affect enzyme activity, including temperature, pH, enzyme/substrate concentration.
Full Transcript
Enzyme. Part 4. Dr. Mohamed Khomsi Fb: محمد الخمسي.د Aug / 2024 Enzyme Table of contents Introduction to Enzymes …………………….….. 1 Cofactors …………………….….. 4 Active Site...
Enzyme. Part 4. Dr. Mohamed Khomsi Fb: محمد الخمسي.د Aug / 2024 Enzyme Table of contents Introduction to Enzymes …………………….….. 1 Cofactors …………………….….. 4 Active Site …………………….….. 9 Function …………………….….. 11 Factors Affecting Enzymes …………………….….. 17 Inhibitors …………………….….. 21 Regulation of Enzymes …………………….….. 26 Isozymes …………………….….. 30 Medical Application of Enzymes …………………….….. 42 □ □ □ Active Site Definition: - It Is a Small Special Pocket or Cleft in an Enzyme where Binding & Catalysis occurs. Sites: - The Active Site Consists of 2 Sites: Binding site Catalytic site Contains amino acid Residues that Contains amino acid Residues that Form Temporary bond with Substrate Catalyse Reaction of Substrate Binding: - The Active Site can Binds & Orients to: (1) Substrate, (2) Cofactor or Prosthetic Group, (3) Competitive Inhibitor. Properties: (1) Small, (2) Active (3) Specific, (4) Reversible. Property Explanation Small Active site Represent
