Clinical Hematology - Introduction to Blood PDF

CLINICAL HEMATOLOGY BLOOD COMPOSITION TOPIC: INTRODUCTION TO BLOOD ENHANCEMENT CLASS INTRODUCTION TO BLOOD CHARACTERISTICS - Blood transports oxygen from lungs to tissue; clears tissues of carbon dioxide; transports glucose, pr...

CLINICAL HEMATOLOGY BLOOD COMPOSITION TOPIC: INTRODUCTION TO BLOOD ENHANCEMENT CLASS INTRODUCTION TO BLOOD CHARACTERISTICS - Blood transports oxygen from lungs to tissue; clears tissues of carbon dioxide; transports glucose, proteins and lipids; and moves wastes - Involves in Physiologic and Pathologic activity of the human body CHARACTERISTICS: Average volume of the human body: 5 liters pH of Blood: 7.35 – 7.45 Specific gravity: 1.045 – 1.065 Body temperature: 98.6-degree Fahrenheit More Viscous than water BLOOD CELLS Red in color Arterial blood: Bright red RED BLOOD CELL Venous blood: Dark red Anucleated Biconcave Contains HEMOGLOBIN SALMON PINK 7 – 8 um in dm FUNCTIONS - Transportation - Regulation NEUTROPHIL (PMN) - Protection 50% - 75% of the total peripheral WBCs in adults. COMPOSITION 10 to 15 um in dm Kills and phagocytose bacteria and other foreign debris PLASMA (55%: WHOLE BLOOD) 90% - Water 8 – 10% Solutes BUFFY COAT (4%: WHOLE BLOOD) Leukocytes Platelets PACKED RED BLOOD CELLS (41%: WHOLE BLOOD) Erythrocytes Fibrinogen (Non – Anticoagulated Tubes) A.R.B LYMPHOCYTE 20% - 40% of the circulating WBCs 7 – 10 um in diameter Effector and regulatory cells for adaptive immunity MONOCYTE 2% - 11% of circulating leukocytes 15 – 20 um Precursors of macrophages and other mononuclear phagocytic cells EOSINOPHIL 1% - 3% of the circulating WBCs in a non-allergic person 12 to 15 um in diameter Kill helminthic and other parasites; modulate local inflammation BASOPHIL 0% - 2% of circulating leukocytes 10 to 15 um in diameter Modulate inflammation, release histamine during allergy A.R.B CLINICAL HEMATOLOGY MCV (MEAN CELL VOLUME): - Measures the average size of red blood cells TOPIC: CBC PARAMETERS MCH (MEAN CELL HEMOGLOBIN): ENHANCEMENT CLASS REFERENCE RANGE CBC PARAMETERS - Hyperchromic - >32 pg RED BLOOD CELL COUNT: - Normochromic – 26 – 32 pg - Method used to detect medical conditions such as - Hypochromic - 36 g/dL - Normochromic – 32 – 36 g/dL - Hypochromic -