Biotransformation I Highlighted PDF

Summary

This document discusses biotransformation, focusing on the processes of detoxification and bioactivation of various compounds. It details the mechanisms and reactions involved in biotransformation, and includes a brief section on organophosphates.

Full Transcript

BIOTRANSFORMATION Mirex What are organophosphates? There are almost 900 different pesticides that can be used in the United States. A small number (37) belong to a class of insect killers (insecticides) known as organophosphates. The chemicals in this class kill insects by disrupting their b...

BIOTRANSFORMATION Mirex What are organophosphates? There are almost 900 different pesticides that can be used in the United States. A small number (37) belong to a class of insect killers (insecticides) known as organophosphates. The chemicals in this class kill insects by disrupting their brains and nervous systems. Unfortunately, these chemicals also can harm the brains and nervous systems of animals and humans. These chemicals stop a key enzyme in the nervous system called cholinesterase from working, and this can make people ill.

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