Biological Levels and Psychology PDF
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Saint Louis University
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This document provides an overview of the relationship between biological levels and psychology. It details various aspects such as the role of dopamine in reward, genetic influences on psychological disorders, and the impact of mitochondrial dysfunction. The document also discusses how brain tissue damage affects behavior, and the body's response to stress.
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Biological Levels and Psychology 1. Molecules: Dopamine regulates reward and motivation Dopamine is a neurotransmitter synthesized in the brain from the amino acid tyrosine. It plays a critical role in the brain’s reward pathway, particularly in the mesolimbic dopamine system. When a rewarding stim...
Biological Levels and Psychology 1. Molecules: Dopamine regulates reward and motivation Dopamine is a neurotransmitter synthesized in the brain from the amino acid tyrosine. It plays a critical role in the brain’s reward pathway, particularly in the mesolimbic dopamine system. When a rewarding stimulus (e.g., food, social interaction) is anticipated or experienced, dopamine levels increase in areas such as the nucleus accumbens. Applications: Deficient dopamine activity is linked to conditions like depression and Parkinson’s disease, while excessive dopamine activity has been associated with schizophrenia and substance addiction. Example in psychology: Behavioral reinforcement theories often cite dopamine’s role in motivating actions by creating pleasurable sensations. 2. Macromolecules: Genetic studies examine links between DNA and psychological disorders like schizophrenia DNA encodes genes that regulate brain development and neurotransmitter production. Variants or mutations in genes like COMT or DISC1 are associated with schizophrenia. These genes influence dopamine metabolism and synaptic connectivity, which are critical for cognitive and emotional functioning. Application: Genome-wide association studies (GWAS) identify genetic risk factors for psychological disorders. This understanding can lead to personalized therapies based on a person’s genetic makeup. Example in Psychology: Genetic counseling for families with a history of schizophrenia involves understanding heritability and environmental interactions. 3. Organelles: Dysfunctional mitochondria linked to neurodegenerative diseases Mitochondria are the cell’s powerhouses, generating ATP (adenosine triphosphate) through oxidative phosphorylation. Neurons, which require high energy, are especially vulnerable to mitochondrial dysfunction. Mutations in mitochondrial DNA or damage from oxidative stress can impair energy production. Application: Mitochondrial dysfunction is implicated in diseases like Alzheimer's (due to beta-amyloid aggregation affecting mitochondrial function) and Parkinson's (linked to mitochondrial mutations in PINK1 or PARKIN genes). Example in Psychology: Therapeutic strategies target mitochondrial health, such as using antioxidants to reduce oxidative stress. 4. Cells: Study of neural pathways to understand learning and memory Neurons transmit information through action potentials and chemical synapses. Long-term potentiation (LTP) and long-term depression (LTD) are cellular mechanisms underlying memory formation. LTP strengthens synaptic connections, often in the hippocampus, a critical brain region for memory. Application: Understanding how synapses change during learning helps develop treatments for conditions like Alzheimer's, where memory is impaired. Example in Psychology: Behavioral therapies often involve repeated exposure or practice to strengthen neural pathways, leveraging principles of neuroplasticity. 5. Tissues: Damage to brain tissue can affect behavior, such as in traumatic brain injury (TBI) Nervous tissue is composed of neurons and glial cells. In TBI, axonal shearing (damage to the connections between neurons) disrupts communication in brain networks. This can lead to cognitive deficits, mood disorders, and changes in personality. Application: Rehabilitation often involves neuropsychological assessments and therapies targeting damaged regions. Example in Psychology: Therapists work with patients to develop compensatory strategies for cognitive or emotional challenges caused by brain tissue damage. 6. Organs: The amygdala regulates fear The amygdala, located in the temporal lobe, is a key structure in the limbic system. It processes emotional stimuli, particularly threats, and activates the autonomic nervous system for fight-or-flight responses. Damage to the amygdala can result in reduced fear responses (as seen in rare cases like Urbach-Wiethe disease). Application: Overactivity in the amygdala is linked to anxiety disorders and PTSD. Techniques like cognitive behavioral therapy (CBT) or exposure therapy aim to reduce maladaptive fear responses. Example in Psychology: Research on phobias often examines amygdala activation during exposure to feared stimuli. 7. Organ Systems: Hypothalamic-pituitary-adrenal (HPA) axis activation in stress response The HPA axis involves the hypothalamus releasing corticotropin-releasing hormone (CRH), which stimulates the pituitary gland to release adrenocorticotropic hormone (ACTH). ACTH then triggers cortisol release from the adrenal glands. Chronic activation of this system can lead to allostatic load (wear and tear on the body), contributing to mental health issues like depression or anxiety. Application: Mindfulness and stress-management techniques aim to regulate the HPA axis by reducing cortisol levels. Example in Psychology: Stress inoculation therapy (SIT) helps individuals develop coping strategies to modulate their stress response. 8. Organism: Humanistic psychology focuses on the whole person and self-actualization Humanistic psychology, developed by theorists like Carl Rogers and Abraham Maslow, emphasizes the integration of biological, psychological, and social dimensions of a person. Self-actualization, at the top of Maslow’s hierarchy of needs, refers to realizing one’s full potential. Application: Humanistic approaches like person-centered therapy focus on empathy, unconditional positive regard, and the client's subjective experience. Example in Psychology: In therapy, individuals are encouraged to explore their identity and purpose, promoting mental well-being through self-fulfillment. Characteristics of Life and Psychology 1. Movement: Developmental psychology studies infant motor coordination; Neuroscience examines Parkinson’s Movement involves the ability to change position or perform motion, crucial in physical and psychological development. Application: - Infant motor coordination: Developmental psychology examines milestones like crawling and walking, which reflect motor and cognitive development. Issues in coordination may indicate developmental delays. - Parkinson’s disease: This neurodegenerative disorder is linked to dopamine deficiency in the basal ganglia, affecting voluntary movement and motor planning. Example in Psychology: Motor skill assessments help identify developmental disorders like cerebral palsy. 2. Responsiveness: Cognitive psychology examines decision-making under threat; Anxiety disorders reflect maladaptive responsiveness Responsiveness is the reaction to changes in the environment, critical for survival and emotional regulation. Application: - Decision-making under threat: Cognitive psychology explores how individuals process and respond to danger, often mediated by the amygdala and prefrontal cortex. - Anxiety disorders: Maladaptive responsiveness, like hyper-reactivity of the amygdala, leads to excessive fear and avoidance behaviors. Example in Psychology: Exposure therapy helps reduce maladaptive fear responses in anxiety disorders. 3. Growth: Piaget’s theory of cognitive development outlines growth stages Growth refers to the increase in size or capacity, which in psychology extends to cognitive, emotional, and social domains. Application: Piaget’s stages—sensorimotor, preoperational, concrete operational, and formal operational—highlight how thinking evolves with age. Example in Psychology: Educators use Piaget’s theory to design age-appropriate learning activities. 4. Reproduction: Studies on attachment and mate selection Reproduction ensures the survival of species and involves psychological aspects like attachment, mating preferences, and parenting behaviors. Application: Evolutionary psychology examines traits that enhance reproductive success, such as mate selection based on genetic fitness. Example in Psychology: Attachment theories explore how early bonds influence parenting styles and mate selection. 5. Respiration: Breathing techniques in mindfulness reduce anxiety; Yoga and relaxation therapies use controlled breathing Respiration involves oxygen intake and carbon dioxide removal, which is linked to stress and relaxation in psychophysiology. Application: - Mindfulness: Focused breathing activates the parasympathetic nervous system, reducing cortisol levels and anxiety. - Yoga therapy: Combines breathing techniques (pranayama) with physical postures to improve mental health. Example in Psychology: Clinical practices use diaphragmatic breathing to manage panic disorders. 6. Digestion: Gut microbiota imbalances linked to depression and anxiety Digestion breaks down food into simpler forms, influencing the gut-brain axis. Imbalances in gut bacteria affect neurotransmitter production, such as serotonin. Application: Research shows probiotics can improve mood and cognitive function by modulating gut microbiota. Example in Psychology: Psychobiotics are being explored as potential treatments for mood disorders. 7. Absorption: Vitamin B12 or omega-3 deficiencies impact mental health Absorption involves nutrients crossing membranes into body fluids, essential for brain health. Application: - Vitamin B12 deficiency: Can lead to memory loss, depression, and fatigue. - Omega-3 fatty acids: Essential for neural membrane integrity and reducing inflammation associated with depression. Example in Psychology: Nutritional interventions are often combined with psychotherapy for holistic mental health treatment. 8. Circulation: Cardiovascular health improves brain function and reduces depression risk Circulation delivers oxygen and nutrients to the brain, ensuring optimal cognitive and emotional functioning. Application: Poor cardiovascular health (e.g., atherosclerosis) is linked to dementia and depression due to reduced blood flow to the brain. Example in Psychology: Physical exercise is recommended in therapy to enhance circulation and boost mood. 9. Assimilation: Piaget’s theory uses assimilation as a key learning process Assimilation involves integrating new information into existing cognitive frameworks. Application: Piaget highlighted how children assimilate experiences to understand the world, modifying their schemas through accommodation. Example in Psychology: Therapists use cognitive restructuring to help patients assimilate healthier thought patterns. 10. Excretion: Renal issues can lead to cognitive impairments or mood disorders Excretion removes metabolic waste products, preventing toxin buildup. Impaired excretion (e.g., kidney failure) can lead to uremic toxins, which affect brain function and mood. Application: Chronic kidney disease patients often experience cognitive deficits and depression due to systemic effects. Example in Psychology: Psychologists work with healthcare teams to support patients managing chronic illnesses. Homeostasis and Its Control Mechanisms 1. Homeostasis - Definition: Homeostasis refers to the maintenance of a stable internal environment in the body despite changes in external conditions. - Significance: It is essential for the survival of organisms as it ensures optimal functioning of cells and biological processes. 2. Homeostatic Control Mechanisms - Homeostatic mechanisms monitor the internal environment and correct any deviations to maintain equilibrium. - These mechanisms work through a feedback loop involving three main components: receptor, control center, and effector. Components of Homeostatic Control Mechanisms 1. Receptor - Function: Detects changes (stimuli) in the internal or external environment. - Example: Thermoreceptors in the skin sense changes in body temperature. 2. Control Center - Function: Processes information received from the receptor and determines the appropriate response by comparing it to the set point (the ideal value). - Example: The hypothalamus in the brain acts as the control center for temperature regulation. 3. Effector - Function: Executes the response to restore balance by either increasing or decreasing the activity. - Example: Sweat glands (cooling the body) or skeletal muscles (shivering to generate heat). Feedback Loops - Negative Feedback: - The most common mechanism to maintain homeostasis. - It reverses a change to bring conditions back to the set point. - Example: Regulation of body temperature: - Stimulus: Body temperature rises above 37°C (98.6°F). - Receptors: Thermoreceptors detect the rise and send signals to the hypothalamus. - Control Center: The hypothalamus compares the temperature to the set point. - Effectors: Sweat glands increase activity, and blood vessels dilate to release heat. - Response: Body temperature decreases back to normal. - Positive Feedback: - Amplifies changes rather than reversing them. - Used in processes that need a rapid or decisive outcome. - Example: Blood clotting or childbirth. Example: Thermoregulation - Normal Body Temperature: ~37°C (98.6°F). - If Temperature Falls: - If Temperature Rises: - Receptor: Thermoreceptors detect low temperature. - Receptor: Thermoreceptors detect high temperature. - Control Center: Hypothalamus initiates heat-conserving - Control Center: Hypothalamus triggers responses to cool the measures. body. - Effector: Blood vessels constrict (vasoconstriction), and - Effector: Sweat glands produce sweat, and blood vessels muscles contract (shivering) to generate heat. dilate (vasodilation), releasing heat.