Adenosine PDF

GENERIC NAME adenosine TRADE, BRAND, OR PROPRIETARY NAME Adenocard® CLASS Antidysrhythmic STANDARD SUPPLIES Prefilled syringe Vial MECHANISM OF ACTION Slows atrioventricular conduction INDICATIONS Supraventricular tachycardia Wolff-Parkinson-White (WPW) syndrome Monomorphic wide-complex tachycardia...

GENERIC NAME adenosine TRADE, BRAND, OR PROPRIETARY NAME Adenocard® CLASS Antidysrhythmic STANDARD SUPPLIES Prefilled syringe Vial MECHANISM OF ACTION Slows atrioventricular conduction INDICATIONS Supraventricular tachycardia Wolff-Parkinson-White (WPW) syndrome Monomorphic wide-complex tachycardia CONTRAINDICATIONS Atrial fibrillation Atrial flutter Polymorphic ventricular tachycardia (Torsades de pointes) Second-degree and third-degree heart block ADVERSE REACTIONS/SIDE EFFECTS Transient dysrhythmias Chest pain Palpitations Nausea Dyspnea Dizziness Hypotension Blurred vision Cardiac arrest Asystole ROUTES OF ADMINISTRATION IV IO ADENOSINE 1 ONSET OF ACTION 20 to 30 seconds ADULT DOSAGES 6.0 mg RAPID bolus over 1 to 3 seconds followed by 20 mL normal saline flush If no response to the initial bolus after 1 to 2 minutes, administer 12 mg RAPID bolus over 1 to 3 seconds followed by 20 mL normal saline flush PEDIATRIC DOSAGES 0.1 mg/kg (up to 6.0 mg) RAPID bolus over 1 to 3 seconds followed by 5 to10 mL normal saline flush If no response to the initial bolus after 1 to 2 minutes, administer 0.2 mg/kg (up to 12 mg) RAPID bolus over 1 to 3 seconds followed by 5.0 to 10 mL normal saline flush SPECIAL CONSIDERATIONS Constant monitoring of the patient’s cardiac rhythm is required during administration of the drug The half-life of the drug is 6 to 10 seconds The peak effect of the drug is 20 to 30 seconds The duration of the drug is 30 seconds ADENOSINE 2