Summary

This presentation discusses chronic kidney disease, including its causes, effects, and management. It covers various aspects such as diabetic nephropathy, hypertension, glomerular disease, and polycystic kidney disease.

Full Transcript

Chronic Kidney Disease Virginia Plummer OFFICIAL Please watch Video: Osmosis Chronic Kidney disease OFFICIAL Chronic Kidney Disease (CKD) Management in Primary Care (5th edition). OFFICIAL Be aware of ne...

Chronic Kidney Disease Virginia Plummer OFFICIAL Please watch Video: Osmosis Chronic Kidney disease OFFICIAL Chronic Kidney Disease (CKD) Management in Primary Care (5th edition). OFFICIAL Be aware of nephrotoxic medications OFFICIAL Diabetic nephropathy High BGL damage efferent arteriole > arteriolosclerosis Back pressure > fibrosis > glomerulosclerosis GFR OFFICIAL Hypertension Thickens afferent arterioles walls, reducing blood flow and pressure within the glomerulus RAAS activated > further elevating BP OFFICIAL Glomerular disease Glomerulonephritis Abnormal Antibodies attack the glomerular basement membrane > inflammatory destruction OFFICIAL Polycystic Kidney Disease (PCKD) Gene defect causes cysts on the tubules of the nephrons Cyst can compress neighbouring nephrons reducing blood flow to tubular cells (affecting reabsorption and secretion of substances. Ischemia and necrosis > reduced GFR GFR OFFICIAL OFFICIAL Renin Angiotensin Aldosterone System (RAAS) 1. How does the RAAS affect Blood Pressure? 2. Why would you use an ACE Inhibitor in the management of chronic kidney failure? OFFICIAL References Australian Institute of Health and Welfare (2024). Chronic kidney disease: Australian facts, About - Australian Institute of Health and Welfare (aihw.gov.au) Brown, D., Buckley, T., Aitken, R., & Edwards, H. (2023). Lewis’s Medical-Surgical Nursing 6th Australia and New Zealand Edition: Assessment and Management of Clinical Problems. Elsevier Health Sciences Craft J., Gordon C., Huether, S., McCance K., Brashers, V. (2023) Understanding Pathophysiology Australia and New Zealand Edition (4thEdition). Elsevier. Kidney Health Australia (2024). Chronic Kidney Disease (CKD) Management in Primary Care (5th edition). Rogers, J. (2023). Chapter 38. Alterations of Renal and Urinary Tract Function, McCance & Huether’s Pathophysiology (Ninth Edition), edited by Rogers Julia L. Pages 1232-1269, ISBN 978-0-323-78987-5, http://dx.doi.org/10.1016/B978-0-323-78987-5.00041-0. (https://www.clinicalkey.com/student/nursing/content/book/3-s2.0-B9780323789875000410)Taylor J (2023) Renal system 4: causes, diagnosis and treatment of chronic kidney disease. Nursing Times; 119: 5, 42-47 OFFICIAL

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