Pituitary, Receptors, and Secretion PDF
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Uploaded by PrudentRainforest
University of Galway
Brendan Higgins
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Summary
These lecture notes cover the pituitary gland and its different secretions. The document details the roles of the hormones; and some questions related to the content. It's aimed at an undergraduate level of physiology.
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Dr Brendan Higgins Discipline of Physiology Rm 3018, Human Biology Building University [email protected] ofGalway.ie Copyright © Learning Objectives University ofGalway.ie The Pi...
Dr Brendan Higgins Discipline of Physiology Rm 3018, Human Biology Building University [email protected] ofGalway.ie Copyright © Learning Objectives University ofGalway.ie The Pituitary Gland: Two Fused Units University ofGalway.ie Cells of the Anterior Pituitary ♀ Acidophils - pink cytoplasm and dark nuclei. Secrete protein hormones like hGH and PRL. Basophils -darker cells with purple cytoplasm, secrete glycoprotein hormones ACTH, TSH, FSH, & LH. Some chromophobes - non-secretory and serve as support cells or precursors to acidophils and basophils (http://medcell.med.yale.edu/systems_cell_biology/endocr ine_systems_lab.php) University ofGalway.ie Endorphins (“endogenous morphine”) University ofGalway.ie Growth Hormone (hGH) (aka Somatotropin) University ofGalway.ie Regulation of hGH Secretion ↓ University ofGalway.ie Regulation of hGH Secretion ↑ ↓ University ofGalway.ie Regulation of hGH Secretion University ofGalway.ie Influence of hGH on Blood Glucose ↓ University ofGalway.ie Growth Hormone Action University ofGalway.ie Type I Cytokine Type Receptors University ofGalway.ie IGF-Binding Proteins University ofGalway.ie Effects of hGH University ofGalway.ie Effects of hGH ↑ ↓ ↑ ↑ University ofGalway.ie https://courses.lumenlearning.com/suny-ap2/chapter/the-pituitary-gland-and-hypothalamus/ Over-secretion of hGH Pre-Puberty - Gigantism ♀ ♂ University ofGalway.ie Robert Wadlow – 8’11.1”. Died 22 yo. Size 36 feet Over-secretion of GH Post-Puberty - Acromegaly University ofGalway.ie Prolactin (PRL) → → +ve feedback ♀ ↑ University ofGalway.ie Regulation of PRL Secretion ↓ (PIH) (PRH) University ofGalway.ie Regulation of PRL Secretion ↑ ♀ m ♂ m ↓ ↑ ↑ Blood samples taken every 20 minutes over 24 hours University ofGalway.ie Functions of Prolactin ↑ ↓ University ofGalway.ie Functions of Prolactin ♀ ♂ ↑ ↑ ↓ ↑ University ofGalway.ie MCQs University ofGalway.ie MCQs University ofGalway.ie
