2024-2025 Basic Drug Knowledge List - Tagged.pdf

UIW Feik School of Pharmacy: Basic Drug Knowledge The purpose of the Basic Drug Knowledge list is to ensure our students have a readily retrievable knowledge of the top 300+ outpatient drugs and the top 50+ inpatient drugs. Readily retrievable knowledge is necessary to provide a framework for higher...

UIW Feik School of Pharmacy: Basic Drug Knowledge The purpose of the Basic Drug Knowledge list is to ensure our students have a readily retrievable knowledge of the top 300+ outpatient drugs and the top 50+ inpatient drugs. Readily retrievable knowledge is necessary to provide a framework for higher-level learning skills. The information provided here is basic, foundational knowledge that will be expanded upon in our curriculum and is essential for safe, effective patient care. This list is not all inclusive of every indication, formulation, route, brand name, side effect, and precaution. Many of the facts included in the “Essential Knowledge” column are important to include in patient counseling. In the infectious diseases sections, antibiotic activity against the most common pathogens is listed; however, the pathogen list is not all-inclusive. All drug information presented in these charts were reviewed by pharmacotherapeutics faculty and a subcommittee of the curriculum committee. All drug information was verified using package inserts, drug information resources (i.e., Lexi- Comp, Micromedex), and professional textbooks. This document is for internal use only and should not be shared or used externally outside of the Feik School of Pharmacy. Abbreviations found throughout document:  PO: oral  IV: intravenous  IM: intramuscular  INH: inhalation  SQ: subcutaneous  CI: contraindicated Other abbreviations are provided below each section as appropriate. Textbook References: DiPiro, J.T., Yee, G.C., Posey, L.M., Haines, S.T., Nolin, T.D., & Ellingrod, V. (2020). Pharmacotherapy: A Pathophysiologic Approach (11th ed.). New York, NY: McGraw-Hill Companies, Inc. Brunton, L.L., Hilal-Dandan, R., & Knollman, B.C. (2018). Goodman and Gilman’s: The Pharmacological Basis of Therapeutics (13th ed.). New York, NY: McGraw-Hill Companies, Inc. Katzung, B.G. (2021). Basic and Clinical Pharmacology (15th ed.). New York, NY: McGraw-Hill Companies, Inc. Last Updated: June 2024  HEAD, EARS, EYES, NOSE, THROAT 1 Pharmacologic Category Generic Name Brand Name Common Indications Essential Knowledge Key Side Effects: ocular hypersensitivity, drowsiness, allergic Alpha2 agonist brimonidine (ophthalmic) Alphagan P Elevated IOP conjunctivitis, conjunctival hyperemia, ocular pruritus Other Notes: CI with MAOI therapy Timoptic, Non-selective timolol (ophthalmic) Timoptic XE, Elevated IOP Key Side Effects: ocular stinging and burning beta-blocker Istalol Elevated IOP, eyelash bimatoprost (ophthalmic) Lumigan, Latisse hypotrichosis Key Side Effects: eyelash growth, conjunctival hyperemia, ocular Prostaglandin analog latanoprost (ophthalmic) Xalatan pruritus, iris color change, periocular hyperpigmentation Elevated IOP travoprost (ophthalmic) Travatan Z Key Side Effects: ocular burning, stinging, pruritus, foreign body Calcineurin inhibitor cyclosporine (ophthalmic) Restasis Keratoconjunctivitis sicca sensation, hypersensitivity reaction Pred Forte, Pred Key Side Effects: glaucoma, cataract formation, corneal thinning, Corticosteroid prednisolone (ophthalmic) Ophthalmic inflammation Mild, Omnipred secondary infection Pediculocide permethrin (topical) * Nix, Elimite Lice, scabies Key Side Effects: itching, redness, swelling of scalp Key Side Effects: xeroderma, skin exfoliation, erythema, stinging, Retinoic acid derivative adapalene (topical) * Differin Acne burning Hibiclens, Skin cleanser, Key Side Effects: dysgeusia, increased tartar formation, mouth Antiseptic chlorhexidine (topical, PO) Peridex periodontitis, gingivitis discoloration, mouth irritation Temovate, Key Side Effects: burning of skin, dryness of skin, clobetasol (topical) Clobex Psoriasis, atopic hypopigmentation, secondary infection Corticosteroid dermatitis Other Notes: do not use for > 2 weeks because it may cause triamcinolone (topical) Kenalog adrenal suppression IOP: intraocular pressure; MAOI: monoamine oxidase inhibitor; *: OTC product available  HEAD, EARS, EYES, NOSE, THROAT 2 Pharmacologic Category Generic Name Brand Name Common Indications Essential Knowledge Key Side Effects: Increased blood pressure, tachycardia, Alpha (α1) agonist pseudoephedrine (PO) * Sudafed Nasal congestion insomnia, restlessness Other notes: Sold behind the counter fluticasone (intranasal) * Flonase Key Side Effects: nasal dryness, epistaxis, nasal burning, Corticosteroid Allergic rhinitis triamcinolone (intranasal) * Nasacort headache Key Side Effects: headache, nasal dryness, epistaxis, bitter azelastine (intranasal) * Astepro Allergic rhinitis taste Allergic rhinitis, Key Side Effects: drowsiness, constipation, xerostomia, urinary diphenhydramine (PO *, IV) Benadryl allergic reaction, retention insomnia Key Side Effects: dizziness, somnolence, xerostomia, blurred Histamine (H1) blocker hydroxyzine (PO, IV) Atarax, Vistaril Pruritis, nausea, anxiety vision, QTc prolongation cetirizine (PO) * Zyrtec loratadine (PO) * Claritin Allergic rhinitis Key Side Effects: drowsiness, dizziness, headache fexofenadine (PO) * Allegra Pataday, olopatadine (ophthalmic) * Allergic conjunctivitis Key Side Effects: ocular burning, discomfort, dryness Patanol Key Side Effects: dizziness, somnolence, xerostomia, blurred vision, constipation, respiratory depression (dose-related) US Boxed Warning: concomitant use of opioids with Histamine (H1) blocker and promethazine and codeine Phenergan with benzodiazepines or other CNS depressants (including alcohol), Cough, cold opioid analgesic (PO) Codeine may result in profound sedation, respiratory depression, coma, and death Other Notes: opioid-containing cough and cold products no longer indicated for use in patients