12-Secretion.pptx PDF
Document Details
Uploaded by ProminentSamarium6001
University of Central Florida
Tags
Summary
The document discusses the system of internal membranes in eukaryotic cells, including the nucleus, endoplasmic reticulum, Golgi apparatus, and their roles in protein secretion and other cellular processes. It describes the traffic through nuclear pores, nuclear localization signals, and the secretion pathway.
Full Transcript
The System of Internal Membranes the eukaryotic cell nucleus traffic through nuclear pores nuclear localization signals nuclear import synthesis of secreted proteins the endoplasmic reticulum the secretion pathway the ER-Golgi intermediate complex the Golgi apparatus exocytosis...
The System of Internal Membranes the eukaryotic cell nucleus traffic through nuclear pores nuclear localization signals nuclear import synthesis of secreted proteins the endoplasmic reticulum the secretion pathway the ER-Golgi intermediate complex the Golgi apparatus exocytosis coated vesicles the lysosome phagocytosis and endocytosis autophagy References: p. 515-524, 526-529,532-534, 539-549 Internal compartments in eukaryotic cells Cells engage in endocytosis and exocytosis Endocytosis: import mediated by the formation of endocytic vesicles. Exocytosis: export (secretion). A continual exchange of materials with the environment involves the plasma membrane, small vesicles, the endoplasmic reticulum, the Golgi apparatus, and lysosomes. Delivery of proteins to organelles and membrane-enclosed compartments in eukaryotic cells Peroxisomes contain enzymes that break down lipids and destroy toxic molecules through oxidation reactions. It is one of the digestive organelles of the cell. The eukaryotic cell nucleus The nuclear envelope is a double membrane. The outer membrane is continuous with the endoplasmic reticulum (ER). The perinuclear space is the cavity between the two membranes. The nuclear pores allow both passive and active transport. The nuclear lamina The inner membrane covered with lamin proteins viewed from inside the nucleus The nuclear lamina The nuclear lamina is a network of lamin protein fibers that lines the inner wall of the nuclear envelope. The lamina provides structural support for the nucleus and attachment sites for the chromatin. When destroyed, the entire nucleus collapses. It is a component of the cytoskeleton and belongs to the category of intermediate filaments. Nuclear pores The nuclear pores contain proteins complexes that facilitate transport through the nuclear envelope. Traffic through nuclear pores Passive diffusion: for small molecules and small proteins (
